NASDAQ$ALEC

Alector Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Alector reported Q4 2025, revenue of $6.2M, a net loss of $37.3M, diluted EPS of $-0.34.

For Q4 2025, Alector reported revenue of $6.2M, a net loss of $37.3M, diluted EPS was $-0.34. Management discusses segment performance, capital allocation, and macro risks in the quarterly filing.

  • Revenue $6.2M.
  • Net loss $37.3M.
  • Diluted EPS $-0.34.

Headline financials

Total Revenue

$6.2M

Previous: $54.2M-88.6%
EPS (adj)

-$0.34

Previous: -$0.02-1600.0%
Net Income

-$37.3M

Previous: -$2.1M-1676.2%
Operating Income

$39.6K

Previous: -$7.25M+100.5%

Revenue & EPS history

Alector · Revenue · Quarterly

$6.2M

Q4 2025-88.6%vs Q4 2024
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Alector · $9.11M total across 1 segment · Q3 2023

  • Collaboration Revenue
    $9.11M-38.7%

Forward guidance

The quarterly filing discusses operating priorities, capital returns, and sector risks; numeric multi-quarter bridges vary by issuer.

Tailwinds

  • MD&A highlights liquidity, capital, and core business trends.
  • Segment or product commentary supports the earnings narrative.

Headwinds

  • Macro, rates, or input costs may pressure near-term margins.
  • One-time items can affect year-over-year comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+1.1%

Avg return

Earnings day

-1.0%

Avg return

5 days after

-5.5%

Avg return

30 days after

52%

15 / 29 earnings

Positive

+32.9%

Q2 2023

Best reaction

-18.4%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-5.1%-16.0%-36.6%
Q4 2025+7.1%-11.7%-16.3%
Q3 2025+4.1%+8.4%-2.8%
Q1 2025+4.2%+7.4%+23.8%
Q4 2024-3.5%-15.4%-25.0%
Q3 2024+12.8%+21.3%-56.8%
Q2 2024+0.8%+0.9%-4.2%
Q1 2024-1.9%+1.7%-17.7%
Q4 2023+7.9%+14.4%-7.1%
Q3 2023-2.6%-17.7%+6.0%
Q2 2023+32.9%+12.4%-15.6%
Q1 2023+13.0%+20.6%+8.5%
Q4 2022+0.9%-9.5%-30.3%
Q3 2022-18.4%+3.1%+3.1%
Q2 2022+16.3%+12.7%-6.9%
Q1 2022-12.7%-20.0%-11.9%
Q4 2021+1.9%-1.3%-7.8%
Q3 2021+2.3%+4.1%-20.7%
Q2 2021+9.5%+9.0%+10.1%
Q1 2021-7.8%-12.4%+6.1%
Q4 2020-4.7%-10.7%-14.3%
Q3 2020+0.4%+7.2%+25.2%
Q2 2020-6.9%-7.4%-13.5%
Q1 2020-5.0%+0.3%+3.7%
Q4 2019-1.5%-4.4%+0.8%
Q3 2019-6.1%-4.2%+19.5%
Q2 2019-1.7%-18.0%+9.4%
Q1 2019+4.9%+1.3%+0.2%
Q4 2018-8.6%-3.5%+10.8%
Q3 2018
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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