NASDAQ$ALEC
Alector Inc · Q2 2025 earnings
Q2 2025 earnings · · After market close · Investor relations
Briefing
Alector Inc reported Q2 2025 results showing collaboration revenue of $7.9 million and a net loss of $30.5 million.
Alector reported collaboration revenue of $7.9 million for the three months ended June 30, 2025, down from $15.1 million in the prior year period due to the satisfaction of certain performance obligations. The company recorded a net loss of $30.5 million and an operating loss of $34.1 million. Cash, cash equivalents, and marketable securities totaled $307.3 million, providing runway into the second half of 2027.
- Collaboration revenue declined to $7.9 million from $15.1 million year-over-year as certain performance obligations were satisfied.
- R&D expenses decreased significantly to $27.6 million from $46.3 million, reflecting reduced program costs and workforce reductions.
- Net loss improved to $30.5 million from $38.7 million, aided by lower operating expenses despite reduced other income.
- Cash position of $307.3 million supports operations into the second half of 2027, with topline data from INFRONT-3 expected in Q4 2025.
Headline financials
Revenue & EPS history
Alector · Revenue · Quarterly
$7.87M
Revenue by segment
Alector · $7.87M total across 1 segment · Q2 2025
- Collaboration revenue$7.87M—100.0%
Forward guidance
Cash runway extends into the second half of 2027; topline data from the INFRONT-3 Phase 3 trial anticipated in mid-Q4 2025.
Tailwinds
- Reduced operating expenses and improved net loss year-over-year.
- Strong cash position supporting long-term operations.
Headwinds
- Declining collaboration revenue due to completed performance obligations.
- Lower interest income from reduced marketable securities and rate cuts.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports
+1.1%
Avg return
Earnings day
-1.0%
Avg return
5 days after
-5.5%
Avg return
30 days after
52%
15 / 29 earnings
Positive
+32.9%
Q2 2023
Best reaction
-18.4%
Q3 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q2 2025 | — | — | — | |
| Q1 2026 | -5.1% | -16.0% | -36.6% | |
| Q4 2025 | +7.1% | -11.7% | -16.3% | |
| Q3 2025 | +4.1% | +8.4% | -2.8% | |
| Q1 2025 | +4.2% | +7.4% | +23.8% | |
| Q4 2024 | -3.5% | -15.4% | -25.0% | |
| Q3 2024 | +12.8% | +21.3% | -56.8% | |
| Q2 2024 | +0.8% | +0.9% | -4.2% | |
| Q1 2024 | -1.9% | +1.7% | -17.7% | |
| Q4 2023 | +7.9% | +14.4% | -7.1% | |
| Q3 2023 | -2.6% | -17.7% | +6.0% | |
| Q2 2023 | +32.9% | +12.4% | -15.6% | |
| Q1 2023 | +13.0% | +20.6% | +8.5% | |
| Q4 2022 | +0.9% | -9.5% | -30.3% | |
| Q3 2022 | -18.4% | +3.1% | +3.1% | |
| Q2 2022 | +16.3% | +12.7% | -6.9% | |
| Q1 2022 | -12.7% | -20.0% | -11.9% | |
| Q4 2021 | +1.9% | -1.3% | -7.8% | |
| Q3 2021 | +2.3% | +4.1% | -20.7% | |
| Q2 2021 | +9.5% | +9.0% | +10.1% | |
| Q1 2021 | -7.8% | -12.4% | +6.1% | |
| Q4 2020 | -4.7% | -10.7% | -14.3% | |
| Q3 2020 | +0.4% | +7.2% | +25.2% | |
| Q2 2020 | -6.9% | -7.4% | -13.5% | |
| Q1 2020 | -5.0% | +0.3% | +3.7% | |
| Q4 2019 | -1.5% | -4.4% | +0.8% | |
| Q3 2019 | -6.1% | -4.2% | +19.5% | |
| Q2 2019 | -1.7% | -18.0% | +9.4% | |
| Q1 2019 | +4.9% | +1.3% | +0.2% | |
| Q4 2018 | -8.6% | -3.5% | +10.8% | |
| Q3 2018 | — | — | — | |
| Q2 2018 | — | — | — | |
| Q1 2018 | — | — | — | |
| Q4 2017 | — | — | — | |
| Q3 2017 | — | — | — | |
| Q2 2017 | — | — | — | |
| Q1 2017 | — | — | — |
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