NASDAQ$ALEC

Alector Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Alector reported Q4 and full year 2023 financial results and provided a business update.

Alector reported a net loss of $41.4 million for the quarter ended December 31, 2023, with collaboration revenue of $15.2 million. The company's cash, cash equivalents, and investments totaled $548.9 million as of December 31, 2023, which is anticipated to provide runway through 2026 after a January 2024 equity offering.

  • Target enrollment achieved in pivotal INFRONT-3 latozinemab Phase 3 trial in FTD-GRN during Q4 2023.
  • Data from INVOKE-2, evaluating the most advanced TREM2 candidate in clinical development for early Alzheimer’s disease (AD), expected in Q4 2024.
  • Latozinemab granted FDA’s Breakthrough Therapy Designation for frontotemporal dementia due to a mutation in the progranulin gene (FTD-GRN).
  • First participant in the global PROGRESS-AD Phase 2 clinical trial of AL101 in early AD dosed in Q1 2024.

Headline financials

Total Revenue

$15.2M

Previous: $14.4M+5.2%
EPS (adj)

-$0.49

Previous: -$0.63+22.2%
Research and Development Expenses

$47.7M

No prior period
General and Administrative Expenses

$14.9M

No prior period
Total Operating Expenses

$62.6M

No prior period
Other Income, Net

$7.69M

No prior period
Loss Before Income Taxes

-$39.8M

No prior period
Income Tax Expense

$1.67M

No prior period
Shares Used in Computing Net Loss Per Share, Basic and Diluted

84.4M

No prior period
Total Current Liabilities (Excluding Deferred Revenue)

$95M

No prior period
Deferred Revenue (Including Current Portion)

$294M

No prior period
Total Liabilities

$488M

No prior period
Total Stockholders' Equity

$134M

No prior period
Capital Expenditures

-$233K

Previous: $766K-130.4%
Net Income

-$41.4M

Previous: -$52.4M+21.0%
Operating Income

-$47.5M

Previous: -$55.4M+14.4%
Gross Profit

$12.9M

Previous: $12.3M+4.9%
R&D Expense

$45.5M

No prior period
Stock-Based Comp

$11.5M

Previous: $11M+5.3%

Revenue & EPS history

Alector · Revenue · Quarterly

$15.2M

Q4 2023+5.2%vs Q4 2022
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Alector · $9.11M total across 1 segment · Q3 2023

  • Collaboration Revenue
    $9.11M-38.7%

Forward guidance

Management anticipates, for the year ending 2024, collaboration revenue to be between $60 million and $70 million, total research and development expenses to be between $210 million and $230 million, and total general and administrative expenses to be between $60 million and $70 million.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+1.1%

Avg return

Earnings day

-1.0%

Avg return

5 days after

-5.5%

Avg return

30 days after

52%

15 / 29 earnings

Positive

+32.9%

Q2 2023

Best reaction

-18.4%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-5.1%-16.0%-36.6%
Q4 2025+7.1%-11.7%-16.3%
Q3 2025+4.1%+8.4%-2.8%
Q1 2025+4.2%+7.4%+23.8%
Q4 2024-3.5%-15.4%-25.0%
Q3 2024+12.8%+21.3%-56.8%
Q2 2024+0.8%+0.9%-4.2%
Q1 2024-1.9%+1.7%-17.7%
Q4 2023+7.9%+14.4%-7.1%
Q3 2023-2.6%-17.7%+6.0%
Q2 2023+32.9%+12.4%-15.6%
Q1 2023+13.0%+20.6%+8.5%
Q4 2022+0.9%-9.5%-30.3%
Q3 2022-18.4%+3.1%+3.1%
Q2 2022+16.3%+12.7%-6.9%
Q1 2022-12.7%-20.0%-11.9%
Q4 2021+1.9%-1.3%-7.8%
Q3 2021+2.3%+4.1%-20.7%
Q2 2021+9.5%+9.0%+10.1%
Q1 2021-7.8%-12.4%+6.1%
Q4 2020-4.7%-10.7%-14.3%
Q3 2020+0.4%+7.2%+25.2%
Q2 2020-6.9%-7.4%-13.5%
Q1 2020-5.0%+0.3%+3.7%
Q4 2019-1.5%-4.4%+0.8%
Q3 2019-6.1%-4.2%+19.5%
Q2 2019-1.7%-18.0%+9.4%
Q1 2019+4.9%+1.3%+0.2%
Q4 2018-8.6%-3.5%+10.8%
Q3 2018
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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