NASDAQ$ZNTL

Zentalis Pharmaceuticals Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Zentalis reported financial results for Q4 and full year 2021, highlighting the Fast Track designation granted to ZN-c3 and the addition of a preclinical BCL-xL degrader candidate.

Zentalis Pharmaceuticals reported its Q4 and full year 2021 financial results, with a cash, cash equivalents, and marketable securities position of $339.9 million as of December 31, 2021. Research and development expenses for the year ended December 31, 2021 were $175.6 million, and general and administrative expenses were $40.9 million.

  • Fast Track designation was granted by the FDA to ZN-c3 for the treatment of uterine serous carcinoma.
  • Two additional trials with ZN-c3 were initiated, including a Phase 2 trial and a Phase 1/2 trial in combination with niraparib in ovarian cancer.
  • A preclinical BCL-xL heterobifunctional degrader candidate was added to the pipeline.
  • The company ended the year with $339.9 million in cash, cash equivalents, and short-term investments.

Headline financials

EPS (adj)

-$1.11

Previous: -$1.01-9.9%
Capital Expenditures

$2.19M

Previous: $661K+231.5%
Free Cash Flow

-$39.2M

Previous: -$28M-40.0%
Net Income

-$50.1M

Previous: -$40.4M-24.1%
Operating Income

-$48.2M

Previous: -$40.2M-19.7%
Cash & Equivalents

$340M

Previous: $339M+0.4%
Total Assets

$455M

Previous: $366M+24.3%
Stock-Based Comp

$8.47M

Previous: $7.89M+7.4%

Revenue & EPS history

Zentalis · Revenue · Quarterly

$400K

Q1 2026

Forward guidance

Zentalis believes that its existing cash, cash equivalents and marketable securities as of December 31, 2021 will be sufficient to fund our operating expenses and capital expenditures requirements into the third quarter of 2023.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-1.4%

Avg return

Earnings day

-2.0%

Avg return

5 days after

+0.8%

Avg return

30 days after

60%

15 / 25 earnings

Positive

+14.5%

Q1 2023

Best reaction

-43.0%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+3.1%-3.2%
Q1 2026+3.9%-1.7%-15.0%
Q3 2025+6.2%+0.8%+9.8%
Q2 2025+5.1%+2.2%+26.8%
Q1 2025-2.5%+3.3%+10.7%
Q4 2024-12.6%-15.0%-23.5%
Q3 2024-2.7%-13.9%-22.3%
Q2 2024-8.8%-12.5%-10.6%
Q1 2024+6.1%+7.0%-5.5%
Q4 2023+10.0%+8.5%+11.9%
Q3 2023-43.0%-45.0%-33.1%
Q2 2023+5.3%+11.2%-0.5%
Q1 2023+14.5%+22.8%+2.7%
Q4 2022+1.2%-2.1%-9.1%
Q3 2022-14.1%-4.3%-17.4%
Q2 2022-0.1%-7.3%-8.1%
Q1 2022-16.4%-24.7%+1.3%
Q4 2021+7.6%+5.7%-3.2%
Q3 2021+0.8%-1.0%-8.8%
Q2 2021+4.9%+7.1%+39.0%
Q1 2021-4.6%-1.3%-9.0%
Q4 2020+1.4%-0.7%+45.7%
Q3 2020-5.6%-2.1%+36.3%
Q2 2020+1.0%+7.2%-10.6%
Q1 2020+4.5%+8.2%+10.5%
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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