NASDAQ$ZNTL

Zentalis Pharmaceuticals Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Zentalis reported third quarter 2022 financial results and provided operational updates.

Zentalis Pharmaceuticals reported a cash balance of $422 million as of September 30, 2022, with a projected cash runway into 2025. The company is advancing its clinical strategy for ZN-c3, including dose optimization and expansion into Cyclin E driven high-grade serous ovarian cancer. Collaborations with Pfizer and GSK are ongoing to explore ZN-c3 in combination therapies.

  • Advanced clinical strategy for ZN-c3 with three-pronged development plan.
  • Identified Cyclin E driven high-grade serous ovarian cancer patients as initial expansion population for ZN-c3 biomarker monotherapy trial.
  • Announced first ZN-c3 clinical development collaboration with Pfizer BRAF-mutant mCRC; Expanded ZN-c3 clinical development collaboration with GSK in PARP resistant ovarian cancer.
  • Declared BCL-xL protein degrader candidate and initiated IND-enabling studies.

Headline financials

EPS (adj)

-$0.96

Previous: -$1.25+23.2%
Capital Expenditures

$1.66M

Previous: $2.66M-37.6%
Free Cash Flow

-$34.9M

Previous: -$36.2M+3.6%
Net Income

-$52.1M

Previous: -$10.5M-396.5%
Operating Income

-$54.2M

Previous: -$62.9M+13.8%
Cash & Equivalents

$422M

Previous: $367M+15.0%
Total Assets

$529M

Previous: $435M+21.6%
Stock-Based Comp

$10.3M

Previous: $7.66M+34.8%

Revenue & EPS history

Zentalis · Revenue · Quarterly

$0

Q3 2025
Beat estimate in 1 of 1 quarters(100%)
ActualEstimate

Forward guidance

Zentalis believes that its existing cash, cash equivalents and marketable securities as of September 30, 2022 will be sufficient to fund its operating expenses and capital expenditure requirements into the first quarter of 2025.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

-1.7%

Avg return

Earnings day

-2.2%

Avg return

5 days after

+2.4%

Avg return

30 days after

58%

14 / 24 earnings

Positive

+14.5%

Q1 2023

Best reaction

-43.0%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.9%-1.7%
Q4 2025+3.1%-3.7%+49.1%
Q3 2025+6.2%+0.8%+9.8%
Q1 2025-2.5%+3.3%+10.7%
Q4 2024-12.6%-15.0%-23.5%
Q3 2024-2.7%-13.9%-22.3%
Q2 2024-8.8%-12.5%-10.6%
Q1 2024+6.1%+7.0%-5.5%
Q4 2023+10.0%+8.5%+11.9%
Q3 2023-43.0%-45.0%-33.1%
Q2 2023+5.3%+11.2%-0.5%
Q1 2023+14.5%+22.8%+2.7%
Q4 2022+1.2%-2.1%-9.1%
Q3 2022-14.1%-4.3%-17.4%
Q2 2022-0.1%-7.3%-8.1%
Q1 2022-16.4%-24.7%+1.3%
Q4 2021+7.6%+5.7%-3.2%
Q3 2021+0.8%-1.0%-8.8%
Q2 2021+4.9%+7.1%+39.0%
Q1 2021-4.6%-1.3%-9.0%
Q4 2020+1.4%-0.7%+45.7%
Q3 2020-5.6%-2.1%+36.3%
Q2 2020+1.0%+7.2%-10.6%
Q1 2020+4.5%+8.2%+10.5%
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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