NASDAQ$ZNTL

Zentalis Pharmaceuticals Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Zentalis reported Q1 2026 net loss of $35.4M with no product revenue.

For the quarter ended March 31, 2026, Zentalis reported a net loss of $35.4 million with no commercial revenue as azenosertib and other oncology programs continue in clinical trials.

  • Net loss $35.4M.
  • Oncology pipeline in clinical development.
  • Cash used for trials and G&A.
  • No product revenue.

Headline financials

Total Revenue

$400K

Previous: $0.00
EPS (adj)

-$0.50

Previous: -$0.67+25.4%
Capital Expenditures

-$34K

Previous: $0.00
Free Cash Flow

-$33M

No prior period
Net Income

-$35.4M

Previous: -$48.3M+26.8%
Operating Income

-$37.9M

Previous: -$45.6M+17.0%
Gross Profit

$400K

No prior period
Cash & Equivalents

$31.9M

No prior period
Total Assets

$253M

No prior period

Revenue & EPS history

Zentalis · Revenue · Quarterly

$400K

Q1 2026
Beat estimate in 1 of 1 quarters(100%)
ActualEstimate

Forward guidance

Clinical readouts drive outlook; no revenue guidance.

Tailwinds

  • Focused precision oncology pipeline.

Headwinds

  • High burn rate.
  • Capital markets dependence.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

-1.4%

Avg return

Earnings day

-2.0%

Avg return

5 days after

+0.8%

Avg return

30 days after

60%

15 / 25 earnings

Positive

+14.5%

Q1 2023

Best reaction

-43.0%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+3.1%-3.2%
Q1 2026+3.9%-1.7%-15.0%
Q3 2025+6.2%+0.8%+9.8%
Q2 2025+5.1%+2.2%+26.8%
Q1 2025-2.5%+3.3%+10.7%
Q4 2024-12.6%-15.0%-23.5%
Q3 2024-2.7%-13.9%-22.3%
Q2 2024-8.8%-12.5%-10.6%
Q1 2024+6.1%+7.0%-5.5%
Q4 2023+10.0%+8.5%+11.9%
Q3 2023-43.0%-45.0%-33.1%
Q2 2023+5.3%+11.2%-0.5%
Q1 2023+14.5%+22.8%+2.7%
Q4 2022+1.2%-2.1%-9.1%
Q3 2022-14.1%-4.3%-17.4%
Q2 2022-0.1%-7.3%-8.1%
Q1 2022-16.4%-24.7%+1.3%
Q4 2021+7.6%+5.7%-3.2%
Q3 2021+0.8%-1.0%-8.8%
Q2 2021+4.9%+7.1%+39.0%
Q1 2021-4.6%-1.3%-9.0%
Q4 2020+1.4%-0.7%+45.7%
Q3 2020-5.6%-2.1%+36.3%
Q2 2020+1.0%+7.2%-10.6%
Q1 2020+4.5%+8.2%+10.5%
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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