NASDAQ$WVE

Wave Life Sciences Ltd · Q3 2024 earnings

Q3 2024 earnings · · Investor relations

Briefing

Announced third quarter 2024 financial results and provided a business update.

Wave Life Sciences reported positive clinical updates across DMD and AATD, achieved first-ever RNA editing in humans, and advanced its pipeline. The company's cash runway is expected into 2027.

  • Achieved first-ever RNA editing in humans in RestorAATion-2 trial of WVE-006 in alpha-1 antitrypsin deficiency.
  • WVE-007 clinical trial on track for 1Q 2025, with preclinical data supporting monotherapy or synergistic use with GLP-1s.
  • Received supportive initial feedback from FDA on WVE-003, with IND submission expected in 2H 2025.
  • Delivered positive interim data from FORWARD-53 study of WVE-N531; expect feedback on a pathway to accelerated approval from regulators in 1Q 2025.

Headline financials

Total Revenue

-$7.68M

Previous: $49.2M-115.6%
EPS (adj)

-$0.47

Previous: $0.07-771.4%
Research and Development Expense

$41.2M

Previous: $31.6M+30.2%
General and Administrative Expense

$15M

Previous: $13.1M+14.6%
Capital Expenditures

-$396K

Previous: -$759K+47.8%
Net Income

-$61.8M

Previous: $7.25M-951.9%
Operating Income

-$63.9M

Previous: $4.44M-1538.2%
Gross Profit

-$7.68M

Previous: $47M-116.3%
R&D Expense

$41.2M

Previous: $31.6M+30.2%

Revenue & EPS history

Wave Life Sciences · Revenue · Quarterly

-$7.68M

Q3 2024-115.6%vs Q3 2023
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Forward guidance

Wave Life Sciences anticipates several milestones across its pipeline, including clinical trial initiations, data readouts, and regulatory feedback.

Tailwinds

  • WVE-007 clinical trial initiation in 1Q 2025.
  • Delivery of complete 48-week FORWARD-53 data in 1Q 2025.
  • Feedback from regulators on a pathway to accelerated approval for WVE-N531 in 1Q 2025.
  • IND submission for WVE-003 expected in 2H 2025.
  • Selection of clinical candidates for PNPLA3, LDLR and APOB in 2025.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2024

Historical avgQ3 2024

+1.9%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+8.2%

Avg return

30 days after

48%

20 / 42 earnings

Positive

+42.4%

Q4 2023

Best reaction

-16.3%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.4%+5.3%-6.9%
Q4 2025+5.6%-7.6%-56.2%
Q3 2025-10.3%-9.9%+157.4%
Q1 2025+0.5%-1.5%+11.2%
Q4 2024+11.7%-6.5%-33.9%
Q3 2024-4.6%-16.8%-15.8%
Q2 2024-9.5%-6.9%-14.2%
Q1 2024-3.9%-0.2%-0.7%
Q4 2023+42.4%+42.0%+23.4%
Q3 2023-8.9%-5.6%-21.7%
Q2 2023+14.4%+3.0%+3.9%
Q1 2023-0.8%+8.2%+23.6%
Q4 2022-11.1%-11.8%+1.9%
Q3 2022-7.6%-19.3%-1.3%
Q2 2022+37.3%+45.1%+26.7%
Q1 2022-16.3%-13.6%+46.3%
Q4 2021-5.7%-17.1%-17.5%
Q3 2021+1.5%-3.2%-25.7%
Q2 2021+7.0%-0.4%+12.3%
Q1 2021+1.5%+9.6%+18.3%
Q4 2020-7.8%-8.9%-40.5%
Q3 2020+2.8%+11.9%+19.3%
Q2 2020+1.5%-0.5%+36.9%
Q1 2020+28.2%+30.2%+28.1%
Q4 2019-3.2%+9.8%+6.6%
Q3 2019-1.0%+3.1%+20.9%
Q2 2019-3.4%-9.4%+3.1%
Q1 2019-0.8%-1.0%-10.7%
Q4 2018+6.1%+7.6%-7.3%
Q3 2018-12.3%-15.3%+4.4%
Q2 2018+10.7%+16.4%+25.7%
Q1 2018-6.9%-9.7%+11.5%
Q4 2017-7.9%-11.7%-10.5%
Q3 2017+3.2%+12.0%+66.5%
Q2 2017-7.7%-12.8%+18.4%
Q1 2017+2.6%+7.9%-2.2%
Q4 2016-2.0%-4.4%-14.8%
Q3 2016+15.3%+18.2%+5.2%
Q2 2016+5.7%+13.5%+26.9%
Q1 2016-2.7%
Q4 2015-3.1%
Q3 2015+11.1%
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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