NASDAQ$WVE

Wave Life Sciences Ltd · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Wave Life Sciences reported financial results for Q1 2023 and provided a business update.

Wave Life Sciences reported a net loss of $27.4 million for the first quarter of 2023. The company's cash and cash equivalents totaled $207.6 million as of March 31, 2023, expected to fund operations into 2025.

  • Launched transformational collaboration with GSK, expected to build patient and shareholder value.
  • Advanced WVE-006 towards CTA submissions for alpha-1 antitrypsin deficiency.
  • Prepared for launch of potentially registrational Phase 2 study of WVE-N531 for boys with DMD.
  • Presented WVE-N531 clinical data at MDA Conference.

Headline financials

Total Revenue

$12.9M

Previous: $1.75M+638.8%
EPS (adj)

-$0.27

Previous: -$0.62+56.5%
Research and Development Expense

$31M

Previous: $27.5M+12.9%
General and Administrative Expense

$12.2M

Previous: $12.4M-1.4%
Capital Expenditures

-$489K

Previous: -$208K-135.1%
Free Cash Flow

-$27.9M

Previous: -$38M+26.6%
Net Income

-$27.4M

Previous: -$37.8M+27.5%
Operating Income

-$30.3M

Previous: -$38.1M+20.5%
Gross Profit

$10.5M

Previous: -$25.7M+140.8%
Cash & Equivalents

$208M

Previous: $61.7M+236.4%
Total Assets

$267M

Previous: $167M+59.7%

Revenue & EPS history

Wave Life Sciences · Revenue · Quarterly

$12.9M

Q1 2023+638.8%vs Q1 2022
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Forward guidance

Wave Life Sciences anticipates several milestones and events related to their drug development programs and platform in the near future.

Tailwinds

  • Initiate dosing in Part B of WVE-N531 potentially registrational Phase 2 clinical trial in 2023
  • Deliver data from Part B in 2024 for WVE-N531
  • Submit CTAs for first-in-human study in 2H 2023 for WVE-006
  • Deliver additional single-dose and multi-dose biomarker and safety clinical data in 2H 2023 for WVE-003
  • Advance collaboration activities with GSK, with potential for additional cash inflows in 2023 and beyond

Headwinds

  • The update in expected timing for HD single-dose clinical data is due to a publicly announced cyber-attack that took place at Wave’s mHTT assay vendor in April 2023.
  • No Wave data or patient samples were impacted by the attack.
  • Wave remains in close contact with the vendor as they address this issue.
  • The company anticipates virtual investor event to be held in the third quarter of 2023.
  • The company will share preclinical data on new wholly-owned programs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

+1.9%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+8.2%

Avg return

30 days after

48%

20 / 42 earnings

Positive

+42.4%

Q4 2023

Best reaction

-16.3%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.4%+5.3%-6.9%
Q4 2025+5.6%-7.6%-56.2%
Q3 2025-10.3%-9.9%+157.4%
Q1 2025+0.5%-1.5%+11.2%
Q4 2024+11.7%-6.5%-33.9%
Q3 2024-4.6%-16.8%-15.8%
Q2 2024-9.5%-6.9%-14.2%
Q1 2024-3.9%-0.2%-0.7%
Q4 2023+42.4%+42.0%+23.4%
Q3 2023-8.9%-5.6%-21.7%
Q2 2023+14.4%+3.0%+3.9%
Q1 2023-0.8%+8.2%+23.6%
Q4 2022-11.1%-11.8%+1.9%
Q3 2022-7.6%-19.3%-1.3%
Q2 2022+37.3%+45.1%+26.7%
Q1 2022-16.3%-13.6%+46.3%
Q4 2021-5.7%-17.1%-17.5%
Q3 2021+1.5%-3.2%-25.7%
Q2 2021+7.0%-0.4%+12.3%
Q1 2021+1.5%+9.6%+18.3%
Q4 2020-7.8%-8.9%-40.5%
Q3 2020+2.8%+11.9%+19.3%
Q2 2020+1.5%-0.5%+36.9%
Q1 2020+28.2%+30.2%+28.1%
Q4 2019-3.2%+9.8%+6.6%
Q3 2019-1.0%+3.1%+20.9%
Q2 2019-3.4%-9.4%+3.1%
Q1 2019-0.8%-1.0%-10.7%
Q4 2018+6.1%+7.6%-7.3%
Q3 2018-12.3%-15.3%+4.4%
Q2 2018+10.7%+16.4%+25.7%
Q1 2018-6.9%-9.7%+11.5%
Q4 2017-7.9%-11.7%-10.5%
Q3 2017+3.2%+12.0%+66.5%
Q2 2017-7.7%-12.8%+18.4%
Q1 2017+2.6%+7.9%-2.2%
Q4 2016-2.0%-4.4%-14.8%
Q3 2016+15.3%+18.2%+5.2%
Q2 2016+5.7%+13.5%+26.9%
Q1 2016-2.7%
Q4 2015-3.1%
Q3 2015+11.1%
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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