NASDAQ$UTHR

United Therapeutics Corp · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

United Therapeutics reported Q1 2026 total revenues of $781.5M and continued Tyvaso franchise mix shift, with total Tyvaso sales down 2% to $457.5M.

Total revenues were $781.5 million (-2% YoY). Tyvaso DPI grew 9% to $330.3 million while nebulized Tyvaso declined 22% to $127.2 million, yielding total Tyvaso revenue of $457.5 million. Remodulin, Orenitram, and Unituxin contributed the balance. Net income metrics are discussed in MD&A with ongoing PAH portfolio competition.

  • Total revenue $781.5M (-2% YoY).
  • Tyvaso DPI $330.3M (+9%); nebulized Tyvaso down 22%.
  • Orenitram $135.6M (+12%).
  • Portfolio transition from nebulized to DPI delivery.

Headline financials

Total Revenue

$782M

Previous: $794M-1.6%
EPS (adj)

$5.82

Previous: $6.63-12.2%
Capital Expenditures

-$101M

Previous: -$74.9M-34.6%
Net Income

$275M

Previous: $322M-14.7%
Operating Income

$326M

Previous: $383M-14.9%
Gross Profit

$648M

Previous: $702M-7.7%

Revenue & EPS history

United Therapeutics · Revenue · Quarterly

$782M

Q1 2026-1.6%vs Q1 2025
Beat estimate in 10 of 15 quarters(67%)
ActualEstimate

Revenue by segment

United Therapeutics · $609M total across 6 segments · Q3 2023

  • Nebulized Tyvaso
    $326M+26.4%
  • Remodulin
    $131M+15.0%
  • Orenitram
    $92M+5.1%
  • Unituxin
    $51.3M+11.3%
  • Adcirca
    $7.3M-31.8%
  • Other
    $1.9M

Forward guidance

The 10-Q discusses label expansions and competitive dynamics in PAH without numeric consolidated EPS guidance.

Tailwinds

  • Tyvaso DPI uptake offsets nebulized erosion.
  • Orenitram growth continues.
  • Diversified rare-cardiopulmonary revenue base.

Headwinds

  • Total revenue slightly down YoY.
  • Remodulin and Unituxin declined.
  • Competitive pressure in PAH therapies.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+0.6%

Avg return

Earnings day

+0.2%

Avg return

5 days after

+1.1%

Avg return

30 days after

57%

39 / 68 earnings

Positive

+16.2%

Q3 2022

Best reaction

-13.0%

Q4 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.3%-0.4%-4.0%
Q4 2025+13.1%+8.5%+10.4%
Q3 2025+9.7%+5.6%+17.0%
Q1 2025+0.8%-0.7%+6.0%
Q4 2024-10.8%-13.3%-14.1%
Q3 2024+6.0%+6.8%+5.0%
Q2 2024-2.9%-3.5%+7.7%
Q1 2024+10.2%+11.2%+17.4%
Q4 2023+1.6%+4.4%+11.1%
Q3 2023+2.4%+2.4%+8.0%
Q2 2023-3.4%-1.0%-5.0%
Q1 2023-5.7%-8.0%-5.1%
Q4 2022-2.7%-3.3%-13.8%
Q3 2022+16.2%+16.8%+22.0%
Q2 2022-1.5%-2.7%-0.8%
Q1 2022+4.1%-0.6%+27.2%
Q4 2021-13.0%-14.0%-9.5%
Q3 2021+4.8%+5.1%-3.2%
Q2 2021+13.7%+15.0%+16.7%
Q1 2021-1.7%-2.8%-9.9%
Q4 2020-2.1%-0.6%-0.7%
Q3 2020+5.6%+8.6%+9.8%
Q2 2020+0.3%+2.9%-6.3%
Q1 2020-0.2%+2.0%+7.5%
Q4 2019-10.7%-8.0%-19.1%
Q3 2019+3.3%+3.6%+6.1%
Q2 2019+4.5%-0.5%+3.8%
Q1 2019-1.3%-1.9%-18.1%
Q4 2018+3.6%-1.5%-3.8%
Q3 2018-6.2%-6.2%-3.7%
Q2 2018+0.3%+0.7%+0.1%
Q1 2018-8.3%-8.3%-4.2%
Q4 2017-12.9%-14.1%-20.4%
Q3 2017+0.2%+0.8%+5.1%
Q2 2017-2.3%-2.6%-2.2%
Q1 2017-1.0%+1.0%-2.2%
Q4 2016-12.2%-9.2%-16.6%
Q3 2016+4.5%+6.0%+19.0%
Q2 2016+6.9%+11.2%+7.6%
Q1 2016-10.6%
Q4 2015-4.2%
Q3 2015+8.8%
Q2 2015+0.8%
Q1 2015-4.4%
Q4 2014+2.3%
Q3 2014-1.9%
Q2 2014+2.7%
Q1 2014+12.4%
Q4 2013-4.1%
Q3 2013+3.8%
Q2 2013+2.7%
Q1 2013-1.6%
Q4 2012+2.7%
Q3 2012+2.9%
Q2 2012+8.3%
Q1 2012+0.8%
Q4 2011-0.9%
Q3 2011+8.0%
Q2 2011+5.0%
Q1 2010-5.3%
Q1 2011+0.8%
Q4 2008+1.8%
Q4 2010+1.8%
Q3 2009+8.0%
Q3 2010+8.0%
Q4 2009-8.2%
Q2 2010-8.2%
Q2 2009-8.2%

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