NASDAQ$URGN

UroGen Pharma Ltd · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

UroGen reported financial results for the fourth quarter and full year ended December 31, 2021, and overview of recent developments.

UroGen Pharma reported a net product revenue of $16.2 million for Q4 2021 from Jelmyto, representing a 42% increase over the previous quarter. The company also announced an up to $100 million senior secured term loan facility to support operations to reach cash flow breakeven by 2025.

  • Jelmyto net product revenue increased 42% over Q3 2021, reaching $16.2 million in Q4 2021.
  • Full-year net product revenue of $48.0 million was in line with guidance.
  • UroGen announced up to $100 million senior secured term loan facility with Pharmakon Advisors, expected to support operations to reach cash flow breakeven by 2025.
  • The first patient was dosed in ENVISION, a single-arm Phase 3 pivotal study for UGN-102 in bladder cancer.

Headline financials

Total Revenue

$16.2M

Previous: $7.97M+103.0%
EPS (adj)

-$1.27

Previous: -$1.38+8.0%
Capital Expenditures

$202K

No prior period
Free Cash Flow

-$20.3M

No prior period
Net Income

-$28.5M

Previous: -$30.5M+6.8%
Operating Income

-$19.9M

Previous: -$27.3M+26.9%
Gross Profit

$14.6M

No prior period
Cash & Equivalents

$89.8M

Previous: $104M-13.6%
Total Assets

$120M

No prior period
Stock-Based Comp

$5.36M

No prior period

Revenue & EPS history

UroGen · Revenue · Quarterly

$16.2M

Q4 2021+103%vs Q4 2020
Beat estimate in 3 of 14 quarters(21%)
ActualEstimate

Revenue by segment

UroGen · $16.2M total across 1 segment · Q4 2021

  • JELMYTO
    $16.2M+102.2%

Forward guidance

The Company anticipates full year 2022 net product revenues from Jelmyto to be in the range of $70 to $80 million. The Company anticipates full year 2022 operating expenses in the range of $140 to $160 million, including non-cash share-based compensation expense of $10 to $16 million, subject to market conditions. The Company anticipates full year 2022 financing expense related to the prepaid obligation to RTW Investments in the range of $22 to $26 million, of which approximately $9.1 to $10.4 million will be in cash.

Tailwinds

  • Full year 2022 net product revenues from Jelmyto to be in the range of $70 to $80 million.
  • Operating expenses are anticipated to be in the range of $140 to $160 million.
  • Non-cash share-based compensation expense of $10 to $16 million is expected.
  • Financing expense related to the prepaid obligation to RTW Investments in the range of $22 to $26 million is anticipated.
  • Approximately $9.1 to $10.4 million will be in cash.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-1.5%

Avg return

Earnings day

-0.9%

Avg return

5 days after

-4.5%

Avg return

30 days after

50%

17 / 34 earnings

Positive

+22.0%

Q3 2025

Best reaction

-28.7%

Q3 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+10.2%+31.3%+12.6%
Q4 2025-12.4%-5.7%-12.7%
Q3 2025+22.0%+22.4%+19.0%
Q1 2025+7.1%-29.6%-29.7%
Q4 2024+1.0%+12.7%+2.9%
Q3 2024-0.9%+4.8%+0.7%
Q2 2024+3.0%+2.0%-10.1%
Q1 2024+1.8%+3.8%-0.2%
Q4 2023-17.2%-14.0%-13.6%
Q3 2023-1.5%+6.0%+29.6%
Q2 2023+7.1%+8.0%-20.0%
Q1 2023+4.8%+2.2%+1.3%
Q4 2022-11.7%-9.1%+0.0%
Q3 2022-18.8%-17.2%-27.6%
Q2 2022-4.3%-5.5%-11.4%
Q1 2022-2.7%-4.0%+13.1%
Q4 2021-1.9%-4.4%-17.3%
Q3 2021-28.7%-37.0%-46.9%
Q2 2021-1.1%-1.8%+14.1%
Q1 2021-16.3%-2.9%-4.7%
Q4 2020+2.4%-0.3%-5.9%
Q3 2020+0.3%-1.9%-22.8%
Q2 2020+4.4%-0.9%-7.7%
Q1 2020-0.2%+2.8%+13.4%
Q4 2019+6.8%+6.8%-39.5%
Q3 2019+8.0%+9.7%+37.9%
Q2 2019-1.2%-0.7%+2.2%
Q1 2019+3.6%+1.9%-1.7%
Q4 2018+4.1%+3.3%-3.8%
Q3 2018+0.7%+1.0%-0.3%
Q2 2018-10.0%-7.1%-3.7%
Q1 2018+1.8%+6.0%-9.9%
Q4 2017-5.8%-7.5%+3.0%
Q3 2017-3.9%-5.2%-14.2%
Q1 2017
Q4 2016
Q3 2016
Q2 2016

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