NASDAQ$TLPH

AcelRx Pharmaceuticals Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

AcelRx (Talphera) narrowed its net loss in Q4 2024 due to reduced operating expenses, though no revenue was recognized.

In Q4 2024, Talphera (formerly AcelRx) reported no revenue, reflecting the transition in its commercial strategy. The company significantly reduced its operating expenses to $3.0 million, down from $4.6 million a year earlier. As a result, the net loss narrowed to $1.87 million, compared to $4.52 million in Q4 2023. Cash and investments stood at $8.86 million at quarter end.

  • No revenue was recognized in Q4 2024, down from $281,000 in Q4 2023.
  • Operating expenses decreased to $3.0 million, reflecting cost reductions.
  • Net loss narrowed to $1.87 million, or $0.07 per share.
  • Cash and investments totaled $8.86 million as of December 31, 2024.

Headline financials

Total Revenue

$0.00

Previous: $281K-100.0%
EPS (adj)

-$0.07

Previous: -$0.25+72.0%
Capital Expenditures

$0.00

No prior period
Net Income

-$1.87M

Previous: -$4.5M+58.4%
Operating Income

-$3M

Previous: -$4.28M+30.0%
Gross Profit

$0.00

Previous: $281K-100.0%
R&D Expense

$1.32M

Previous: $1.77M-25.2%

Revenue & EPS history

AcelRx · Revenue · Quarterly

$0

Q4 2024-100%vs Q4 2023
Beat estimate in 4 of 7 quarters(57%)
ActualEstimate

Forward guidance

Talphera expects continued advancement in its NEPHRO CRRT study following FDA protocol changes and new financing support, positioning the company to complete the study by end of 2025.

Tailwinds

  • FDA approval to reduce NEPHRO CRRT study size from 166 to 70 patients
  • Expanded inclusion criteria allow broader patient enrollment
  • Private placement financing up to $14.8 million secured
  • Strong clinical enthusiasm for Niyad's anticoagulant potential
  • New trial sites expected to boost enrollment pace in H1 2025

Headwinds

  • Zero revenue recognized in Q4 2024
  • Ongoing net losses reflect limited commercial activity
  • Execution risk tied to NEPHRO CRRT trial completion
  • Stock price dependency for access to full financing tranches
  • Limited operating runway without additional financing beyond trial

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

-2.7%

Avg return

Earnings day

-3.4%

Avg return

5 days after

-0.3%

Avg return

30 days after

32%

20 / 62 earnings

Positive

+23.5%

Q4 2017

Best reaction

-46.9%

Q4 2014

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.7%-7.0%
Q3 2025-18.6%+3.9%-7.8%
Q2 2025+0.0%+14.0%+118.6%
Q1 2025-3.9%+2.0%-3.9%
Q4 2024+6.0%+2.0%+2.0%
Q3 2024-2.2%-25.3%-28.6%
Q2 2024-5.5%+2.2%-1.1%
Q1 2024-1.0%+4.9%-4.9%
Q4 2025+0.0%-1.9%+1.9%
Q4 2023+1.6%-12.0%-4.0%
Q3 2023-9.7%-11.5%+40.4%
Q2 2023-7.4%-18.9%-8.4%
Q1 2023+14.5%+14.5%+79.7%
Q4 2022-8.3%-16.7%-6.9%
Q3 2022+22.3%+16.0%+22.3%
Q2 2022+12.5%+33.3%+16.7%
Q1 2022+4.8%+23.8%-4.8%
Q4 2021-22.7%-29.5%-38.6%
Q3 2021-10.1%-8.9%-34.2%
Q2 2021-20.5%-10.3%-12.8%
Q1 2021+11.2%+9.5%-94.1%
Q4 2020-16.2%-21.6%-38.3%
Q3 2020-20.8%-21.3%-16.9%
Q2 2020-7.6%-0.8%-12.9%
Q1 2020-1.3%-9.7%-11.0%
Q4 2019-7.8%-18.4%+25.2%
Q3 2019-1.5%-12.3%-7.9%
Q2 2019-5.8%-7.4%-4.1%
Q1 2019-10.7%-10.1%-34.8%
Q4 2018-9.4%-14.4%-4.4%
Q3 2018+2.9%-14.5%-18.8%
Q2 2018+5.7%+7.5%+17.0%
Q1 2018+0.0%+2.0%+48.0%
Q4 2017+23.5%+26.5%+29.4%
Q3 2017+1.5%-5.1%+7.7%
Q2 2017-24.4%-25.6%-15.4%
Q1 2017-3.7%-7.4%-16.7%
Q4 2016+11.5%+3.3%+3.3%
Q3 2016-3.6%-7.1%+1.8%
Q2 2016+19.8%+17.8%+5.9%
Q1 2016-6.2%
Q4 2015-8.7%
Q3 2015+13.5%
Q2 2015+8.0%
Q1 2015-24.6%
Q4 2014-46.9%
Q3 2014+14.7%
Q2 2014-5.1%
Q1 2014-5.6%
Q4 2013+7.0%
Q3 2013-0.4%
Q2 2013-12.9%
Q1 2013-3.6%
Q4 2012-5.0%
Q3 2012-5.8%
Q2 2012-2.3%
Q1 2012+0.0%
Q4 2011-5.9%
Q3 2011-0.7%
Q2 2011+2.8%
Q1 2011+5.1%
Q4 2010-3.1%
Q3 2010
Q2 2010
Q1 2010

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