NASDAQ$TLPH
AcelRx Pharmaceuticals Inc · Q2 2025 earnings
Q2 2025 earnings · · After market close · Investor relations
Briefing
Talphera reported a net loss and no revenue in Q2 2025, with lower operating expenses compared to the same quarter last year.
Talphera posted a net loss of $3.5 million in Q2 2025, with zero revenue. Operating expenses were reduced year-over-year, driven by cost control measures. Cash and cash equivalents stood at $6.8 million at quarter-end.
- Net loss narrowed to $3.5 million from $3.8 million in Q2 2024.
- No revenue was reported in Q2 2025.
- Cash and cash equivalents totaled $6.8 million as of June 30, 2025.
- Operating expenses declined due to reduced personnel and administrative costs.
Headline financials
Revenue & EPS history
AcelRx · Revenue · Quarterly
$0
Forward guidance
Talphera expects full-year 2025 cash operating expenses to range between $16 million and $17 million, with continued enrollment in the NEPHRO trial and additional clinical sites expected to be active.
Tailwinds
- NEPHRO study enrollment ahead of schedule with 15 patients enrolled
- Expected completion of NEPHRO trial by end of 2025
- Addition of six new high-enrolling clinical sites in Q3 2025
- Strong interest from clinical sites for nafamostat
- Stock-based compensation excluded from lowered expense forecast
Headwinds
- Zero revenue for the quarter
- Continued net losses from operations
- Limited cash runway with $6.8 million in reserves
- Success dependent on enrollment milestones for financing tranches
- Regulatory and development risks remain for lead product candidate
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q2 2025
-2.7%
Avg return
Earnings day
-3.4%
Avg return
5 days after
-0.3%
Avg return
30 days after
32%
20 / 62 earnings
Positive
+23.5%
Q4 2017
Best reaction
-46.9%
Q4 2014
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +4.7% | -7.0% | — | |
| Q3 2025 | -18.6% | +3.9% | -7.8% | |
| Q2 2025 | +0.0% | +14.0% | +118.6% | |
| Q1 2025 | -3.9% | +2.0% | -3.9% | |
| Q4 2024 | +6.0% | +2.0% | +2.0% | |
| Q3 2024 | -2.2% | -25.3% | -28.6% | |
| Q2 2024 | -5.5% | +2.2% | -1.1% | |
| Q1 2024 | -1.0% | +4.9% | -4.9% | |
| Q4 2025 | +0.0% | -1.9% | +1.9% | |
| Q4 2023 | +1.6% | -12.0% | -4.0% | |
| Q3 2023 | -9.7% | -11.5% | +40.4% | |
| Q2 2023 | -7.4% | -18.9% | -8.4% | |
| Q1 2023 | +14.5% | +14.5% | +79.7% | |
| Q4 2022 | -8.3% | -16.7% | -6.9% | |
| Q3 2022 | +22.3% | +16.0% | +22.3% | |
| Q2 2022 | +12.5% | +33.3% | +16.7% | |
| Q1 2022 | +4.8% | +23.8% | -4.8% | |
| Q4 2021 | -22.7% | -29.5% | -38.6% | |
| Q3 2021 | -10.1% | -8.9% | -34.2% | |
| Q2 2021 | -20.5% | -10.3% | -12.8% | |
| Q1 2021 | +11.2% | +9.5% | -94.1% | |
| Q4 2020 | -16.2% | -21.6% | -38.3% | |
| Q3 2020 | -20.8% | -21.3% | -16.9% | |
| Q2 2020 | -7.6% | -0.8% | -12.9% | |
| Q1 2020 | -1.3% | -9.7% | -11.0% | |
| Q4 2019 | -7.8% | -18.4% | +25.2% | |
| Q3 2019 | -1.5% | -12.3% | -7.9% | |
| Q2 2019 | -5.8% | -7.4% | -4.1% | |
| Q1 2019 | -10.7% | -10.1% | -34.8% | |
| Q4 2018 | -9.4% | -14.4% | -4.4% | |
| Q3 2018 | +2.9% | -14.5% | -18.8% | |
| Q2 2018 | +5.7% | +7.5% | +17.0% | |
| Q1 2018 | +0.0% | +2.0% | +48.0% | |
| Q4 2017 | +23.5% | +26.5% | +29.4% | |
| Q3 2017 | +1.5% | -5.1% | +7.7% | |
| Q2 2017 | -24.4% | -25.6% | -15.4% | |
| Q1 2017 | -3.7% | -7.4% | -16.7% | |
| Q4 2016 | +11.5% | +3.3% | +3.3% | |
| Q3 2016 | -3.6% | -7.1% | +1.8% | |
| Q2 2016 | +19.8% | +17.8% | +5.9% | |
| Q1 2016 | -6.2% | — | — | |
| Q4 2015 | -8.7% | — | — | |
| Q3 2015 | +13.5% | — | — | |
| Q2 2015 | +8.0% | — | — | |
| Q1 2015 | -24.6% | — | — | |
| Q4 2014 | -46.9% | — | — | |
| Q3 2014 | +14.7% | — | — | |
| Q2 2014 | -5.1% | — | — | |
| Q1 2014 | -5.6% | — | — | |
| Q4 2013 | +7.0% | — | — | |
| Q3 2013 | -0.4% | — | — | |
| Q2 2013 | -12.9% | — | — | |
| Q1 2013 | -3.6% | — | — | |
| Q4 2012 | -5.0% | — | — | |
| Q3 2012 | -5.8% | — | — | |
| Q2 2012 | -2.3% | — | — | |
| Q1 2012 | +0.0% | — | — | |
| Q4 2011 | -5.9% | — | — | |
| Q3 2011 | -0.7% | — | — | |
| Q2 2011 | +2.8% | — | — | |
| Q1 2011 | +5.1% | — | — | |
| Q4 2010 | -3.1% | — | — | |
| Q3 2010 | — | — | — | |
| Q2 2010 | — | — | — | |
| Q1 2010 | — | — | — |
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