NASDAQ$STRO

Sutro Biopharma Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Sutro reported full year 2023 financial results with business highlights and anticipated milestones.

Sutro Biopharma reported its full year 2023 financial results, highlighting the initiation of the REFRαME-O1 study of luvelta and the advancement of earlier stage programs. The company also strengthened its management team and cash position.

  • Initiated REFRαME-O1, a registration-directed study of luvelta for platinum-resistant ovarian cancer (PROC) patients.
  • Advanced earlier stage programs.
  • Strengthened management team with the promotion of Jane Chung to President and Chief Operating Officer.
  • Bolstered cash position with additional non-dilutive capital.

Headline financials

Total Revenue

$114M

Previous: $8.63M+1217.4%
EPS (adj)

$0.52

Previous: -$0.61+185.2%
Cash Runway

365

No prior period
Capital Expenditures

-$1.44M

No prior period
Net Income

-$107M

Previous: -$37.1M-187.9%
Operating Income

-$89.3M

Previous: -$49.2M-81.4%
Gross Profit

$112M

Previous: $6.47M+1629.8%
R&D Expense

$53.8M

No prior period
Stock-Based Comp

$6.22M

Previous: $5.85M+6.3%

Revenue & EPS history

Sutro · Revenue · Quarterly

$114M

Q4 2023+1,217.4%vs Q4 2022
Beat estimate in 11 of 16 quarters(69%)
ActualEstimate

Revenue by segment

Sutro · $14.5M total across 2 segments · Q1 2026

  • Astellas Pharma Inc.
    $14.5M
  • Vaxcyte, Inc.
    $15K

Forward guidance

Sutro anticipates continuing momentum in 2024 with the initiation of a second registration-directed trial with luvelta, REFRαME-P1, for pediatric patients with CBF/GLIS AML, and two additional planned INDs.

Tailwinds

  • Initiation of REFRαME-P1 trial for pediatric patients with CBF/GLIS AML planned.
  • Two additional INDs planned.
  • Continued clinical development planned in combination with bevacizumab for the treatment of ovarian cancer.
  • Continued clinical development planned in combination with bevacizumab for the treatment of endometrial cancer.
  • IND submission planned for STRO-003, a ROR1-targeting ADC, in 2024.

Headwinds

  • Current market conditions provide a challenging financing environment.
  • Evaluating programs and spending.
  • Potential delays in clinical trial enrollment.
  • Uncertainties in regulatory approvals.
  • Risks related to commercial collaborations with third parties.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

-0.8%

Avg return

Earnings day

-0.7%

Avg return

5 days after

+6.4%

Avg return

30 days after

42%

13 / 31 earnings

Positive

+22.2%

Q4 2023

Best reaction

-29.4%

Q4 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.1%-20.2%
Q4 2025+2.8%+14.5%+63.3%
Q3 2025-15.8%-13.8%-7.9%
Q2 2025-2.1%-4.9%+29.3%
Q1 2025-3.8%-1.1%-3.3%
Q4 2024-11.7%-20.3%+21.6%
Q3 2024-15.4%-32.6%-48.0%
Q2 2024+10.8%+29.9%+37.3%
Q1 2024+4.6%-3.4%-6.0%
Q4 2023+22.2%+65.2%+1.5%
Q3 2023+13.9%+29.3%+88.9%
Q2 2023+0.9%+1.2%+7.1%
Q1 2023+1.6%-4.1%-5.3%
Q4 2022-3.1%-9.6%-10.7%
Q3 2022-2.5%-3.7%+4.6%
Q2 2022+14.6%+23.1%-2.4%
Q1 2022-6.8%-19.6%-19.2%
Q4 2021-2.5%-8.0%-8.3%
Q3 2021-5.3%-11.3%-32.2%
Q2 2021-0.2%+2.3%+12.4%
Q1 2021+8.3%+9.7%-0.5%
Q4 2020+4.2%-3.7%-16.5%
Q3 2020+17.8%+12.4%+62.7%
Q2 2020+1.7%+1.0%+48.9%
Q1 2020-9.8%-8.1%+0.4%
Q4 2019-29.4%-19.9%-3.4%
Q3 2019-1.1%-1.2%-7.5%
Q2 2019-7.0%-3.8%+19.6%
Q1 2019-7.6%-7.9%+1.8%
Q4 2018+5.4%-1.2%-12.6%
Q3 2018-5.0%-13.1%-23.2%
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

Discussion

Share your read of this quarter. Sign-in carries your eToro identity.

Join the conversation

Sign in with eToro to post your read of this quarter and vote on others'.

Sign in with eToro