NASDAQ$STRO

Sutro Biopharma Inc · Q4 2020 earnings

Q4 2020 earnings · · Investor relations

Briefing

Sutro Biopharma reported its financial results, business highlights, and provided a preview of anticipated milestones.

Sutro Biopharma reported full year 2020 financial results, highlighting a net cash increase of $193.0 million during 2020 and year-end cash, cash equivalents and marketable securities of $326.5 million. The company also progressed its clinical development programs and collaborations with partners like Merck, Bristol Myers Squibb, and EMD Serono.

  • Year-end 2020 cash, cash equivalents and marketable securities totaled $326.5 million, projecting runway into the second half of 2023.
  • Four antibody-drug conjugate programs discovered through Sutro’s platform are now in the clinic.
  • Partner EMD Serono's bispecific ADC, M1231, advanced into the clinic.
  • Dosing of initial patients in dose-expansion of the Phase 1 STRO-002 study was initiated in January 2021.

Headline financials

Total Revenue

$8.28M

Previous: $11.3M-26.8%
EPS (adj)

-$1.48

Previous: -$0.65-127.7%
Net Income

-$32.1M

Previous: -$55.7M+42.4%
Operating Income

-$71.1M

Previous: -$55.5M-28.1%
Gross Profit

-$14.5M

No prior period
Cash & Equivalents

$326M

Previous: $133M+144.6%
Total Assets

$394M

Previous: $156M+152.0%
Stock-Based Comp

$3.09M

No prior period

Revenue & EPS history

Sutro · Revenue · Quarterly

$8.28M

Q4 2020-26.8%vs Q4 2019
Beat estimate in 5 of 10 quarters(50%)
ActualEstimate

Revenue by segment

Sutro · $14.5M total across 2 segments · Q1 2026

  • Astellas Pharma Inc.
    $14.5M
  • Vaxcyte, Inc.
    $15K

Forward guidance

Sutro Biopharma anticipates continued progress in its clinical programs and collaborations, with key milestones expected in 2021.

Tailwinds

  • Continued progress in Phase 1 trial of STRO-002, with additional data expected in the first half of 2021.
  • Dose-expansion portion of the Phase 1 trial for STRO-002 began enrolling patients in January 2021, with initial data expected in the second half of 2021.
  • Phase 1 dose-escalation continues for STRO-001, with interim data presented at ASH in December 2020.
  • Collaboration with Merck is advancing two cytokine derivative programs towards the clinic.
  • Phase 1 trial for CC-99712 (BCMA-targeted ADC) continues to enroll multiple myeloma patients.

Headwinds

  • The timing and results of biotechnology development and potential regulatory approval is inherently uncertain.
  • The company's ability to advance its product candidates is subject to risks and uncertainties.
  • The impact of the COVID-19 pandemic may affect the Company’s business, clinical trial sites, supply chain and manufacturing facilities.
  • The Company's ability to fund development activities and achieve development goals is subject to risks.
  • The Company's ability to protect intellectual property is subject to risks.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2020

Historical avgQ4 2020

-0.8%

Avg return

Earnings day

-1.3%

Avg return

5 days after

+3.4%

Avg return

30 days after

42%

13 / 31 earnings

Positive

+22.2%

Q4 2023

Best reaction

-29.4%

Q4 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+2.8%-1.6%
Q1 2026-3.1%-20.2%-27.0%
Q3 2025-15.8%-13.8%-7.9%
Q2 2025-2.1%-4.9%+29.3%
Q1 2025-3.8%-1.1%-3.3%
Q4 2024-11.7%-20.3%+21.6%
Q3 2024-15.4%-32.6%-48.0%
Q2 2024+10.8%+29.9%+37.3%
Q1 2024+4.6%-3.4%-6.0%
Q4 2023+22.2%+65.2%+1.5%
Q3 2023+13.9%+29.3%+88.9%
Q2 2023+0.9%+1.2%+7.1%
Q1 2023+1.6%-4.1%-5.3%
Q4 2022-3.1%-9.6%-10.7%
Q3 2022-2.5%-3.7%+4.6%
Q2 2022+14.6%+23.1%-2.4%
Q1 2022-6.8%-19.6%-19.2%
Q4 2021-2.5%-8.0%-8.3%
Q3 2021-5.3%-11.3%-32.2%
Q2 2021-0.2%+2.3%+12.4%
Q1 2021+8.3%+9.7%-0.5%
Q4 2020+4.2%-3.7%-16.5%
Q3 2020+17.8%+12.4%+62.7%
Q2 2020+1.7%+1.0%+48.9%
Q1 2020-9.8%-8.1%+0.4%
Q4 2019-29.4%-19.9%-3.4%
Q3 2019-1.1%-1.2%-7.5%
Q2 2019-7.0%-3.8%+19.6%
Q1 2019-7.6%-7.9%+1.8%
Q4 2018+5.4%-1.2%-12.6%
Q3 2018-5.0%-13.1%-23.2%
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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