NASDAQ$STRO

Sutro Biopharma Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Sutro Biopharma Inc reported $14.5 million in revenue and a net loss of $38.5 million for the first quarter of 2026.

Sutro Biopharma reported revenue of $14.5 million for Q1 2026, primarily from its collaboration with Astellas, compared to $17.4 million in the prior year period. The company narrowed its net loss to $38.5 million from $76.0 million year-over-year, driven by reduced operating expenses following its restructuring plans. Sutro completed a $110 million equity offering in February 2026 and believes its $202.6 million in cash, cash equivalents, and marketable securities will fund operations for at least the next 12 months.

  • Revenue declined 17% year-over-year to $14.5 million, driven by lower collaboration revenue from Astellas and Vaxcyte.
  • Net loss improved to $38.5 million from $76.0 million in Q1 2025 due to a 49% reduction in operating expenses following workforce reductions.
  • Completed a $110 million public offering of common stock in February 2026, strengthening the balance sheet with $202.6 million in cash and marketable securities.
  • Restructuring plans substantially completed in Q1 2026, with focus shifted to preclinical ADC programs STRO-004, STRO-006, and STRO-227.

Headline financials

Total Revenue

$14.5M

Previous: $17.4M-16.5%
EPS (adj)

-$2.94

Previous: -$0.91-223.1%
Net Income

-$38.5M

Previous: -$76M+49.3%
Operating Income

-$29.7M

Previous: -$68.5M+56.7%
Cash & Equivalents

$73.7M

No prior period
Total Assets

$242M

No prior period

Revenue & EPS history

Sutro · Revenue · Quarterly

$14.5M

Q1 2026-16.5%vs Q1 2025
Beat estimate in 11 of 16 quarters(69%)
ActualEstimate

Revenue by segment

Sutro · $14.5M total across 2 segments · Q1 2026

  • Astellas Pharma Inc.
    $14.5M
  • Vaxcyte, Inc.
    $15K

Forward guidance

Cash, cash equivalents and marketable securities of $202.6 million expected to fund operations for at least 12 months following the filing date.

Tailwinds

  • Completed $110 million equity offering in February 2026
  • Restructuring substantially completed with reduced operating expenses
  • Focus on advancing preclinical ADC pipeline

Headwinds

  • Continued net losses and need for additional capital in the future
  • Revenue dependent on collaboration milestones and performance

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

-0.8%

Avg return

Earnings day

-0.7%

Avg return

5 days after

+6.4%

Avg return

30 days after

42%

13 / 31 earnings

Positive

+22.2%

Q4 2023

Best reaction

-29.4%

Q4 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.1%-20.2%
Q4 2025+2.8%+14.5%+63.3%
Q3 2025-15.8%-13.8%-7.9%
Q2 2025-2.1%-4.9%+29.3%
Q1 2025-3.8%-1.1%-3.3%
Q4 2024-11.7%-20.3%+21.6%
Q3 2024-15.4%-32.6%-48.0%
Q2 2024+10.8%+29.9%+37.3%
Q1 2024+4.6%-3.4%-6.0%
Q4 2023+22.2%+65.2%+1.5%
Q3 2023+13.9%+29.3%+88.9%
Q2 2023+0.9%+1.2%+7.1%
Q1 2023+1.6%-4.1%-5.3%
Q4 2022-3.1%-9.6%-10.7%
Q3 2022-2.5%-3.7%+4.6%
Q2 2022+14.6%+23.1%-2.4%
Q1 2022-6.8%-19.6%-19.2%
Q4 2021-2.5%-8.0%-8.3%
Q3 2021-5.3%-11.3%-32.2%
Q2 2021-0.2%+2.3%+12.4%
Q1 2021+8.3%+9.7%-0.5%
Q4 2020+4.2%-3.7%-16.5%
Q3 2020+17.8%+12.4%+62.7%
Q2 2020+1.7%+1.0%+48.9%
Q1 2020-9.8%-8.1%+0.4%
Q4 2019-29.4%-19.9%-3.4%
Q3 2019-1.1%-1.2%-7.5%
Q2 2019-7.0%-3.8%+19.6%
Q1 2019-7.6%-7.9%+1.8%
Q4 2018+5.4%-1.2%-12.6%
Q3 2018-5.0%-13.1%-23.2%
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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