NASDAQ$SMMT

Summit Therapeutics Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

Summit Therapeutics reported financial results for Q4 2024, highlighting an increase in operating expenses and a net loss.

Summit Therapeutics reported a net loss of $61.2 million for Q4 2024. Operating expenses increased due to higher research and development costs. The company continued clinical advancements, particularly with ivonescimab, including partnerships and ongoing Phase III trials.

  • Net loss for Q4 2024 was $61.2 million, compared to $36.6 million in Q4 2023.
  • Operating expenses for Q4 2024 totaled $65.8 million, driven by research and development investments.
  • The company had $412.3 million in cash and cash equivalents as of December 31, 2024.
  • Significant progress was made in clinical trials, including collaborations with Pfizer on ivonescimab.

Headline financials

Total Revenue

$0.00

Previous: -$297K+100.0%
EPS (adj)

-$0.07

Previous: -$0.05-40.0%
GAAP R&D Expenses

$51.4M

Previous: $24.8M+107.3%
GAAP G&A Expenses

$14.2M

Previous: $11.6M+22.4%
Non-GAAP Operating Expenses

$54.6M

No prior period
Non-GAAP Net Loss

-$50.2M

No prior period
Capital Expenditures

-$12K

Previous: $2K-700.4%
Net Income

-$61.2M

Previous: -$36.6M-67.2%
Operating Income

-$65.6M

Previous: -$36.2M-81.2%
Gross Profit

-$22K

Previous: $0.00
R&D Expense

$51.4M

Previous: $24.8M+107.3%

Revenue & EPS history

Summit Therapeutics · Revenue · Quarterly

$0

Q4 2024-100%vs Q4 2023
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Summit Therapeutics remains focused on advancing its pipeline, particularly ivonescimab, with multiple Phase III trials in progress. Financial resources are expected to support ongoing R&D and operational expansion.

Tailwinds

  • Enrollment completed for Phase III HARMONi trial in advanced NSCLC.
  • Fast Track designation granted by the FDA for ivonescimab in combination with chemotherapy.
  • Clinical trial collaboration with Pfizer for potential new treatment combinations.
  • Strong cash position of $412.3 million to support ongoing operations.
  • Expansion of HARMONi-3 trial to include additional NSCLC patient groups.

Headwinds

  • Net losses continue to widen, with $61.2 million reported in Q4 2024.
  • Increased operating expenses due to expanded R&D activities.
  • No reported revenue, reflecting ongoing investment in drug development.
  • Uncertainty around clinical trial outcomes and regulatory approvals.
  • Potential dilution risks from future financing activities.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

-2.5%

Avg return

Earnings day

-0.5%

Avg return

5 days after

+6.7%

Avg return

30 days after

29%

12 / 42 earnings

Positive

+48.6%

Q1 2021

Best reaction

-18.9%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+1.2%+3.1%+7.3%
Q3 2025-4.6%-8.1%-21.1%
Q1 2025+12.9%-1.5%-26.2%
Q4 2024-14.8%-6.5%-10.1%
Q3 2024-14.8%-8.6%-15.4%
Q2 2024-6.2%+7.6%+24.8%
Q1 2024+3.3%+13.7%+121.0%
Q4 2023-18.9%-8.5%-30.0%
Q3 2023-16.3%-12.6%+1.8%
Q2 2023+1.7%+13.1%-12.0%
Q1 2023-18.9%-27.4%-17.5%
Q4 2022-2.0%+14.5%+0.7%
Q3 2022-2.0%+2.9%+284.3%
Q2 2022+1.9%-2.9%+24.0%
Q1 2022+5.4%-6.3%-14.5%
Q4 2021+8.3%+19.0%-25.2%
Q3 2021-5.4%-0.9%-12.0%
Q2 2021-2.2%-7.9%-19.8%
Q1 2021+48.6%+56.4%+22.2%
Q4 2020-4.3%-5.2%-12.3%
Q3 2020-5.6%-9.3%+14.4%
Q2 2020-0.9%-5.2%-4.3%
Q4 2019-13.8%+3.2%-2.9%
Q1 2020-2.7%-5.1%-11.3%
Q3 2019-2.6%-3.6%+0.7%
Q2 2019-7.4%-9.1%-4.6%
Q1 2019-12.5%-2.4%-6.9%
Q4 2018+4.0%+7.4%+8.6%
Q3 2018-10.1%-12.9%+11.5%
Q2 2018-2.6%-4.3%-19.7%
Q1 2018-1.4%-4.4%-81.8%
Q3 2017-3.0%-2.9%-6.2%
Q2 2017+4.3%+3.0%-2.5%
Q1 2017+4.9%+2.9%+15.9%
Q4 2016-2.2%+1.2%-15.6%
Q3 2016-4.5%-6.3%+4.7%
Q2 2016-7.3%-6.1%+78.7%
Q1 2016-4.9%
Q3 2015+1.9%
Q2 2015-0.9%
Q4 2014-4.3%
Q1 2015-4.3%
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q4 2012
Q3 2012
Q2 2012
Q1 2012
Q4 2011
Q3 2011

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