NASDAQ$SMMT

Summit Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · After market close · Investor relations

Briefing

Summit Therapeutics Inc reported a net loss of $565.7 million for the second quarter of 2025.

The company incurred significantly higher operating expenses driven by stock-based compensation and R&D activities related to ivonescimab development. Net loss increased substantially year-over-year with no revenue generated during the period.

  • Net loss of $565.7 million for Q2 2025 compared to $62.9 million in Q1 2025.
  • R&D expenses totaled $208.0 million, reflecting ongoing clinical trials for ivonescimab.
  • G&A expenses reached $360.4 million, primarily due to $350.2 million in stock-based compensation.
  • EPS of $(0.76) with 742.6 million weighted average shares outstanding.

Headline financials

EPS (adj)

-$0.76

Previous: -$0.05-1420.0%
Research and development expenses

$208M

Previous: $30.8M+575.4%
General and administrative expenses

$360M

Previous: $13.8M+2511.7%
Net Income

-$566M

Previous: -$60.4M-836.6%
Operating Income

-$568M

Previous: -$59.6M-853.8%

Revenue & EPS history

Summit Therapeutics · Revenue · Quarterly

$0

Q3 2025
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports

Historical avg

-2.5%

Avg return

Earnings day

-0.5%

Avg return

5 days after

+6.7%

Avg return

30 days after

29%

12 / 42 earnings

Positive

+48.6%

Q1 2021

Best reaction

-18.9%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025———
Q4 2025+1.2%+3.1%+7.3%
Q3 2025-4.6%-8.1%-21.1%
Q1 2025+12.9%-1.5%-26.2%
Q4 2024-14.8%-6.5%-10.1%
Q3 2024-14.8%-8.6%-15.4%
Q2 2024-6.2%+7.6%+24.8%
Q1 2024+3.3%+13.7%+121.0%
Q4 2023-18.9%-8.5%-30.0%
Q3 2023-16.3%-12.6%+1.8%
Q2 2023+1.7%+13.1%-12.0%
Q1 2023-18.9%-27.4%-17.5%
Q4 2022-2.0%+14.5%+0.7%
Q3 2022-2.0%+2.9%+284.3%
Q2 2022+1.9%-2.9%+24.0%
Q1 2022+5.4%-6.3%-14.5%
Q4 2021+8.3%+19.0%-25.2%
Q3 2021-5.4%-0.9%-12.0%
Q2 2021-2.2%-7.9%-19.8%
Q1 2021+48.6%+56.4%+22.2%
Q4 2020-4.3%-5.2%-12.3%
Q3 2020-5.6%-9.3%+14.4%
Q2 2020-0.9%-5.2%-4.3%
Q4 2019-13.8%+3.2%-2.9%
Q1 2020-2.7%-5.1%-11.3%
Q3 2019-2.6%-3.6%+0.7%
Q2 2019-7.4%-9.1%-4.6%
Q1 2019-12.5%-2.4%-6.9%
Q4 2018+4.0%+7.4%+8.6%
Q3 2018-10.1%-12.9%+11.5%
Q2 2018-2.6%-4.3%-19.7%
Q1 2018-1.4%-4.4%-81.8%
Q3 2017-3.0%-2.9%-6.2%
Q2 2017+4.3%+3.0%-2.5%
Q1 2017+4.9%+2.9%+15.9%
Q4 2016-2.2%+1.2%-15.6%
Q3 2016-4.5%-6.3%+4.7%
Q2 2016-7.3%-6.1%+78.7%
Q1 2016-4.9%——
Q3 2015+1.9%——
Q2 2015-0.9%——
Q1 2015-4.3%——
Q4 2014-4.3%——
Q3 2014———
Q2 2014———
Q1 2014———
Q4 2013———
Q3 2013———
Q2 2013———
Q1 2013———
Q4 2012———
Q3 2012———
Q2 2012———
Q1 2012———
Q4 2011———
Q3 2011———

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