NASDAQ$SMMT

Summit Therapeutics Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Summit Therapeutics' Q4 2023 financial results reflect increased R&D spending due to ivonescimab development and updated cash guidance extending operations into Q1 2025.

Summit Therapeutics reported a GAAP net loss of $36.6 million for Q4 2023, driven by increased R&D expenses related to ivonescimab. The company updated its cash guidance, now expecting sufficient funds to operate into the first quarter of 2025, following an extension of a $100 million note.

  • Actively enrolling two Phase III clinical studies in NSCLC for ivonescimab: HARMONi and HARMONi-3.
  • Updated Phase II data for ivonescimab showed a 24-month OS rate of 64.8% in 1L Squamous NSCLC patients and mOS of 22.5 months in 2L+ EGFRm, TKI-progressed NSCLC patients.
  • SITC 2023 poster presentation highlighted novel cooperative binding characteristics of ivonescimab.
  • Updated guidance extends cash runway for operations into Q1 2025.

Headline financials

Total Revenue

-$297K

Previous: $866.49-34380.9%
EPS (adj)

-$0.05

Previous: -$0.07+28.6%
GAAP R&D Expenses

$24.8M

Previous: $5.39M+360.5%
GAAP G&A Expenses

$11.6M

Previous: $7.58M+53.1%
Capital Expenditures

$2K

Previous: -$10K+120.0%
Net Income

-$36.6M

Previous: -$19.2M-90.3%
Operating Income

-$36.2M

Previous: -$20.3M-78.3%
Gross Profit

$0.00

No prior period
R&D Expense

$24.8M

No prior period
Stock-Based Comp

$8.75M

Previous: $2.66M+229.3%

Revenue & EPS history

Summit Therapeutics · Revenue · Quarterly

-$297K

Q4 2023-34,380.9%vs Q4 2022
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Summit Therapeutics updated its cash guidance, now expecting sufficient funds to operate into the first quarter of 2025 due to the extension of a $100 million note.

Tailwinds

  • Sufficient cash to operate into Q1 2025.
  • Extension of $100 million note.
  • Actively enrolling two Phase III clinical studies in NSCLC for ivonescimab
  • Positive Phase II data for ivonescimab showing promising OS rates
  • Novel cooperative binding characteristics of ivonescimab highlighted at SITC 2023

Headwinds

  • GAAP net loss of $36.6 million for Q4 2023
  • Increased R&D expenses related to ivonescimab development
  • Non-GAAP net loss of $27.9 million for Q4 2023
  • Continued investment in clinical trials and development activities.
  • Dependence on Akeso for ivonescimab development and commercialization outside of Summit's territories.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

-2.5%

Avg return

Earnings day

-0.5%

Avg return

5 days after

+6.7%

Avg return

30 days after

29%

12 / 42 earnings

Positive

+48.6%

Q1 2021

Best reaction

-18.9%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+1.2%+3.1%+7.3%
Q3 2025-4.6%-8.1%-21.1%
Q1 2025+12.9%-1.5%-26.2%
Q4 2024-14.8%-6.5%-10.1%
Q3 2024-14.8%-8.6%-15.4%
Q2 2024-6.2%+7.6%+24.8%
Q1 2024+3.3%+13.7%+121.0%
Q4 2023-18.9%-8.5%-30.0%
Q3 2023-16.3%-12.6%+1.8%
Q2 2023+1.7%+13.1%-12.0%
Q1 2023-18.9%-27.4%-17.5%
Q4 2022-2.0%+14.5%+0.7%
Q3 2022-2.0%+2.9%+284.3%
Q2 2022+1.9%-2.9%+24.0%
Q1 2022+5.4%-6.3%-14.5%
Q4 2021+8.3%+19.0%-25.2%
Q3 2021-5.4%-0.9%-12.0%
Q2 2021-2.2%-7.9%-19.8%
Q1 2021+48.6%+56.4%+22.2%
Q4 2020-4.3%-5.2%-12.3%
Q3 2020-5.6%-9.3%+14.4%
Q2 2020-0.9%-5.2%-4.3%
Q4 2019-13.8%+3.2%-2.9%
Q1 2020-2.7%-5.1%-11.3%
Q3 2019-2.6%-3.6%+0.7%
Q2 2019-7.4%-9.1%-4.6%
Q1 2019-12.5%-2.4%-6.9%
Q4 2018+4.0%+7.4%+8.6%
Q3 2018-10.1%-12.9%+11.5%
Q2 2018-2.6%-4.3%-19.7%
Q1 2018-1.4%-4.4%-81.8%
Q3 2017-3.0%-2.9%-6.2%
Q2 2017+4.3%+3.0%-2.5%
Q1 2017+4.9%+2.9%+15.9%
Q4 2016-2.2%+1.2%-15.6%
Q3 2016-4.5%-6.3%+4.7%
Q2 2016-7.3%-6.1%+78.7%
Q1 2016-4.9%
Q3 2015+1.9%
Q2 2015-0.9%
Q4 2014-4.3%
Q1 2015-4.3%
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q4 2012
Q3 2012
Q2 2012
Q1 2012
Q4 2011
Q3 2011

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