NASDAQ$QURE
uniQure NV · Q2 2023 earnings
Q2 2023 earnings · · Investor relations
Briefing
uniQure reported encouraging interim analysis data from Phase I/II clinical trial of AMT-130 in Huntington’s disease and is preparing to initiate two Phase I/II clinical trials in refractory temporal lobe epilepsy and SOD1-ALS later this year.
uniQure announced its financial results for the second quarter of 2023, highlighting encouraging data from its AMT-130 Huntington's disease trial and preparations for new clinical trials. The company's cash position is strong with $628.6 million, excluding a $100 million milestone received in July.
- Announced encouraging interim analysis data from Phase I/II clinical trial of AMT-130 in Huntington’s disease showing preservation of function compared to baseline and clinical benefits relative to natural history.
- Preparations underway to initiate two Phase I/II clinical trials in refractory temporal lobe epilepsy and SOD1-ALS later this year; IND for Fabry disease expected to be submitted in the second half of 2023.
- Strong cash position of $628.6 million as of June 30, 2023, which excludes a $100 million milestone related to first commercial sale of HEMGENIX® in the U.S. received in July 2023.
- Announced sale of royalty interest in HEMGENIX® for up to $400 million.
Headline financials
Revenue & EPS history
uniQure · Revenue · Quarterly
$2.42M
Forward guidance
The company provided forward-looking statements regarding its ability to fund operations into 2026, continued progress on the commercialization of HEMGENIX®, clinical benefits for patients treated with AMT-130, the timing of patient enrollment in the AMT-130 clinical trial, submission of an investigational new drug application for Fabry disease in 2023, initiation of a Phase I/II clinical study of AMT-162 for the treatment of ALS in the second half of 2023, submission of an investigational new drug application or initiation of a Phase I/II clinical study of AMT-260 for rTLE in the second half of 2023, and interactions with regulatory agencies in the first quarter of 2024.
Tailwinds
- Continued progress on the commercialization of HEMGENIX®
- Clinical benefits for patients treated with AMT-130
- Patient enrollment in the AMT-130 clinical trial
- Submission of an investigational new drug application for Fabry disease in 2023
- Initiation of a Phase I/II clinical study of AMT-162 for the treatment of ALS in the second half of 2023
Headwinds
- Risks associated with the regulatory approval and commercial launch of HEMGENIX®
- Material changes to interim or preliminary data
- Impact of financial and geopolitical events
- Risks related to the Commercialization and License Agreement with CSL Behring
- Risks related to clinical development activities, clinical results, collaboration arrangements, regulatory oversight, product commercialization and intellectual property claims and ongoing litigation
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q2 2023
+1.0%
Avg return
Earnings day
+2.2%
Avg return
5 days after
+2.6%
Avg return
30 days after
59%
27 / 46 earnings
Positive
+47.1%
Q2 2015
Best reaction
-32.7%
Q4 2025
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +2.5% | +34.0% | +35.5% | |
| Q4 2025 | -32.7% | -8.7% | +8.1% | |
| Q3 2025 | -6.0% | +7.5% | -27.5% | |
| Q1 2025 | +3.3% | +17.0% | +15.8% | |
| Q4 2024 | +3.4% | -2.9% | +6.9% | |
| Q3 2024 | +28.8% | +40.1% | +18.5% | |
| Q2 2024 | -4.6% | -1.3% | -23.6% | |
| Q1 2024 | +3.6% | +4.2% | +12.5% | |
| Q4 2023 | -14.8% | -23.6% | -23.0% | |
| Q3 2023 | +6.5% | -0.8% | +19.5% | |
| Q2 2023 | -3.0% | -9.2% | -16.0% | |
| Q1 2023 | +2.7% | +1.2% | -3.8% | |
| Q4 2022 | +5.0% | +6.2% | +1.3% | |
| Q3 2022 | +4.4% | +0.1% | +38.2% | |
| Q2 2022 | -25.5% | -20.2% | -18.4% | |
| Q1 2022 | +6.6% | -2.0% | -5.2% | |
| Q4 2021 | +5.9% | +13.0% | +4.5% | |
| Q3 2021 | -0.3% | +7.1% | +2.2% | |
| Q2 2021 | +8.5% | +11.5% | +10.7% | |
| Q1 2021 | +0.7% | -0.3% | +12.3% | |
| Q4 2020 | -2.0% | -11.5% | -8.2% | |
| Q3 2020 | -10.6% | -7.0% | +7.0% | |
| Q2 2020 | +10.7% | +12.0% | +3.7% | |
| Q1 2020 | +1.0% | -3.2% | +6.6% | |
| Q4 2019 | +1.5% | +1.4% | -11.3% | |
| Q3 2019 | -0.8% | +3.9% | +13.4% | |
| Q2 2019 | -8.5% | -9.1% | -17.1% | |
| Q1 2019 | -2.0% | +2.4% | +5.4% | |
| Q4 2018 | +7.7% | +11.8% | +12.1% | |
| Q3 2018 | +9.0% | +0.5% | +20.1% | |
| Q2 2018 | +6.6% | +9.3% | +21.9% | |
| Q1 2018 | -0.3% | -3.2% | +15.7% | |
| Q4 2017 | -13.5% | -17.2% | +16.9% | |
| Q3 2017 | -2.6% | +4.4% | +4.4% | |
| Q2 2017 | +7.2% | +5.1% | +4.8% | |
| Q1 2017 | +2.3% | +3.3% | +6.6% | |
| Q4 2016 | +1.0% | -3.1% | -10.5% | |
| Q3 2016 | -6.2% | -3.9% | -20.6% | |
| Q1 2016 | +11.8% | +16.8% | -38.5% | |
| Q3 2015 | -12.0% | — | — | |
| Q1 2015 | -2.3% | — | — | |
| Q2 2015 | +47.1% | — | — | |
| Q4 2014 | -7.5% | — | — | |
| Q2 2014 | +10.9% | — | — | |
| Q4 2013 | +3.0% | — | — | |
| Q1 2014 | +0.4% | — | — | |
| Q3 2013 | — | — | — | |
| Q2 2013 | — | — | — | |
| Q1 2013 | — | — | — | |
| Q4 2012 | — | — | — | |
| Q3 2012 | — | — | — |
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