NASDAQ$QURE

uniQure NV · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

uniQure reported its financial results for Q4 2023 and highlighted recent progress across its business.

uniQure announced its Q4 and full year 2023 financial results. The company's cash position is expected to fund operations into the second quarter of 2027. Strategic reorganization is expected to deliver $180 million of cost savings over the next three years.

  • Presented promising clinical update from U.S. and European Phase I/II trials of AMT-130 in Huntington’s disease.
  • Announced FDA clearance of two Investigational New Drug (IND) applications.
  • Announced strategic reorganization to advance multiple clinical-stage programs and deliver $180 million of cost savings over the next three years.
  • Cash position of approximately $618 million as of December 31, 2023 expected to fund operations into the second quarter of 2027.

Headline financials

Total Revenue

$6.69M

Previous: $103M-93.5%
EPS (adj)

-$1.53

Previous: $0.15-1120.0%
Capital Expenditures

-$1.97M

Previous: $5.07M-138.8%
Net Income

-$309M

Previous: -$127M-143.3%
Operating Income

-$62.7M

Previous: $26.5M-336.6%
Gross Profit

-$6.33M

Previous: $101M-106.2%
R&D Expense

$42.2M

No prior period
Stock-Based Comp

$7.04M

Previous: $11.9M-40.9%

Revenue & EPS history

uniQure · Revenue · Quarterly

$6.69M

Q4 2023-93.5%vs Q4 2022
Beat estimate in 4 of 15 quarters(27%)
ActualEstimate

Forward guidance

uniQure's forward-looking statements include plans to announce additional follow up data from the ongoing U.S. and European Phase I/II clinical studies of AMT-130, plans to initiate interactions with regulatory authorities regarding the further development of AMT-130, and plans to initiate patient enrollment for AMT-260, AMT-162 and AMT-191 in the first half of 2024.

Tailwinds

  • Company’s cash runway and its ability to fund its operations into the second quarter of 2027
  • Company’s expected cost savings related to its strategic reorganization
  • Company’s plans to announce additional follow up data from the ongoing U.S. and European Phase I/II clinical studies of AMT-130
  • Company’s plans to initiate interactions with regulatory authorities regarding the further development of AMT-130 and the timing of regulatory clarity from such interactions
  • Company’s plans to initiate patient enrollment for AMT-260, AMT-162 and AMT-191 in the first half of 2024

Headwinds

  • Risks associated with the clinical results and the development and timing of the Company’s programs
  • Company’s interactions with regulatory authorities, which may affect the initiation, timing and progress of clinical trials and pathways to approval
  • Company’s ability to continue to build and maintain the company infrastructure and personnel needed to achieve its goals
  • Company’s effectiveness in managing current and future clinical trials and regulatory processes
  • The impact of global economic uncertainty, rising inflation, rising interest rates or market disruptions on its business

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+1.0%

Avg return

Earnings day

+2.2%

Avg return

5 days after

+2.6%

Avg return

30 days after

59%

27 / 46 earnings

Positive

+47.1%

Q2 2015

Best reaction

-32.7%

Q4 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.5%+34.0%+35.5%
Q4 2025-32.7%-8.7%+8.1%
Q3 2025-6.0%+7.5%-27.5%
Q1 2025+3.3%+17.0%+15.8%
Q4 2024+3.4%-2.9%+6.9%
Q3 2024+28.8%+40.1%+18.5%
Q2 2024-4.6%-1.3%-23.6%
Q1 2024+3.6%+4.2%+12.5%
Q4 2023-14.8%-23.6%-23.0%
Q3 2023+6.5%-0.8%+19.5%
Q2 2023-3.0%-9.2%-16.0%
Q1 2023+2.7%+1.2%-3.8%
Q4 2022+5.0%+6.2%+1.3%
Q3 2022+4.4%+0.1%+38.2%
Q2 2022-25.5%-20.2%-18.4%
Q1 2022+6.6%-2.0%-5.2%
Q4 2021+5.9%+13.0%+4.5%
Q3 2021-0.3%+7.1%+2.2%
Q2 2021+8.5%+11.5%+10.7%
Q1 2021+0.7%-0.3%+12.3%
Q4 2020-2.0%-11.5%-8.2%
Q3 2020-10.6%-7.0%+7.0%
Q2 2020+10.7%+12.0%+3.7%
Q1 2020+1.0%-3.2%+6.6%
Q4 2019+1.5%+1.4%-11.3%
Q3 2019-0.8%+3.9%+13.4%
Q2 2019-8.5%-9.1%-17.1%
Q1 2019-2.0%+2.4%+5.4%
Q4 2018+7.7%+11.8%+12.1%
Q3 2018+9.0%+0.5%+20.1%
Q2 2018+6.6%+9.3%+21.9%
Q1 2018-0.3%-3.2%+15.7%
Q4 2017-13.5%-17.2%+16.9%
Q3 2017-2.6%+4.4%+4.4%
Q2 2017+7.2%+5.1%+4.8%
Q1 2017+2.3%+3.3%+6.6%
Q4 2016+1.0%-3.1%-10.5%
Q3 2016-6.2%-3.9%-20.6%
Q1 2016+11.8%+16.8%-38.5%
Q3 2015-12.0%
Q1 2015-2.3%
Q2 2015+47.1%
Q4 2014-7.5%
Q2 2014+10.9%
Q4 2013+3.0%
Q1 2014+0.4%
Q3 2013
Q2 2013
Q1 2013
Q4 2012
Q3 2012

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