NASDAQ$PRTA

Prothena Corporation plc · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Reported financial results for the first quarter of 2024 and provided business highlights.

Prothena reported a net loss of $72.2 million for the first quarter of 2024, with total revenue of $0.1 million. The company's cash and restricted cash position at the end of the quarter was $548.7 million. The company continues to advance its pipeline of investigational therapeutics.

  • Net cash used in operating and investing activities was $73.2 million in the first quarter of 2024; quarter-end cash and restricted cash position was $548.7 million.
  • Advanced potential best-in-class Alzheimer’s disease portfolio: initial data supportive of ongoing Phase 1 clinical trial for PRX012; received FDA clearance for IND application and Fast Track designation for PRX123; Phase 2 clinical trial initiated for BMS-986446 by partner Bristol Myers Squibb.
  • Strengthened leadership position in the amyloidosis community with ongoing enrollment of the confirmatory Phase 3 AFFIRM-AL clinical trial of birtamimab; published birtamimab mechanism of action and pharmacological characteristics in Leukemia & Lymphoma in April 2024.
  • Daniel G. Welch appointed to Prothena Board of Directors as an independent director and Chair Designate

Headline financials

Total Revenue

$50K

Previous: $2.17M-97.7%
EPS

-$1.34

Previous: -$0.89-50.6%
R&D Expenses

$64.1M

No prior period
G&A Expenses

$17.5M

No prior period
Total Non-Cash SBC Expense

$12.4M

No prior period
Capital Expenditures

-$103K

Previous: -$48K-114.6%
Free Cash Flow

-$72.3M

Previous: -$46.9M-54.2%
Net Income

-$72.2M

Previous: -$46.9M-54.1%
Operating Income

-$81.5M

Previous: -$56.3M-44.7%
R&D Expense

$64.1M

No prior period
Stock-Based Comp

$12.4M

Previous: $8.79M+40.9%

Revenue & EPS history

Prothena · Revenue · Quarterly

$50K

Q1 2024-97.7%vs Q1 2023
Beat estimate in 3 of 14 quarters(21%)
ActualEstimate

Revenue by segment

Prothena · $84.9M total across 1 segment · Q3 2023

  • Collaboration Revenue
    $84.9M+5557.7%

Forward guidance

The Company continues to expect the full year 2024 net cash used in operating and investing activities to be $208 to $225 million and expects to end the year with approximately $405 million in cash, cash equivalents and restricted cash (midpoint).

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+1.5%

Avg return

Earnings day

+0.4%

Avg return

5 days after

+0.2%

Avg return

30 days after

57%

30 / 53 earnings

Positive

+45.3%

Q4 2020

Best reaction

-12.0%

Q1 2016

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.1%-8.7%-16.5%
Q4 2025-0.2%-1.7%-3.1%
Q3 2025+5.2%+7.6%+9.8%
Q1 2025+5.2%-3.0%-23.8%
Q4 2024+2.0%-4.6%-15.0%
Q3 2024-4.7%-22.5%-23.6%
Q2 2024+6.7%+3.7%+5.6%
Q1 2024-6.5%-12.0%-10.2%
Q4 2023+2.7%+0.9%-4.5%
Q3 2023+2.4%-0.7%-4.9%
Q2 2023-8.7%-9.7%-18.3%
Q1 2023+17.2%+13.0%+2.9%
Q4 2022+4.6%+7.0%-9.7%
Q3 2022-8.8%-6.6%+8.6%
Q2 2022-8.5%-2.8%-19.1%
Q1 2022-4.7%-13.7%-12.0%
Q4 2021-9.6%-8.3%+5.1%
Q3 2021-0.7%-4.8%-21.5%
Q2 2021+5.0%+5.8%+30.5%
Q1 2021-6.6%-1.8%+90.3%
Q4 2020+45.3%+46.2%+46.5%
Q3 2020+20.9%+7.3%+1.5%
Q2 2020+3.5%+1.5%+8.2%
Q1 2020-7.9%-0.8%-11.7%
Q4 2019-0.1%+0.9%-22.7%
Q3 2019-3.1%-3.0%+32.7%
Q2 2019+2.4%-2.2%-1.3%
Q1 2019+2.7%-1.9%-16.2%
Q4 2018+3.1%+4.3%+12.5%
Q3 2018+0.6%-4.1%-9.8%
Q2 2018+2.7%+8.2%+3.6%
Q1 2018-2.4%+13.1%-1.2%
Q4 2017+8.0%+11.6%+18.1%
Q3 2017-9.2%-8.6%-34.4%
Q2 2017-4.2%-7.1%-1.3%
Q1 2017+11.2%+12.2%+3.2%
Q4 2016+1.4%+5.9%+3.9%
Q3 2016-5.6%-8.3%+14.3%
Q2 2016+2.8%+2.3%-7.9%
Q1 2016-12.0%
Q4 2015+1.4%
Q3 2015+10.9%
Q2 2015-1.1%
Q1 2015-8.5%
Q4 2014-0.2%
Q3 2014-6.0%
Q2 2014+12.2%
Q1 2014+1.0%
Q4 2013+0.5%
Q3 2013+4.7%
Q2 2013-1.6%
Q1 2013+11.9%
Q4 2012+0.6%
Q3 2012
Q2 2012
Q1 2012

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