NASDAQ$PRME

Prime Medicine Inc · Q2 2023 earnings

Q2 2023 earnings · · Investor relations

Briefing

Prime Medicine reported financial results for Q2 2023 and provided business updates.

Prime Medicine reported a net loss of $42.4 million for the second quarter of 2023. As of June 30, 2023, cash, cash equivalents, investments and restricted cash were $221.1 million. The company expects these funds to be sufficient to fund operating expenses and capital expenditure requirements into 2025.

  • Advanced a diversified portfolio of Prime Editing programs.
  • Entered into a research collaboration with Cimeio Therapeutics to develop Prime Edited Shielded Cell and Immunotherapy Pairs™ (SCIP).
  • PM359, product candidate for the treatment of CGD, is progressing well.
  • Presented new preclinical data at the ASGCT Annual Meeting demonstrating the potential for Prime Editing to correct the causative mutation of CGD and showcased the potential application of the PASSIGE™ platform.

Headline financials

EPS (adj)

-$0.47

No prior period
R&D Expenses

$34.6M

No prior period
G&A Expenses

$10.7M

No prior period
Capital Expenditures

$1.98M

No prior period
Free Cash Flow

-$42.8M

No prior period
Net Income

-$42.4M

No prior period
Operating Income

-$45.3M

No prior period
Cash & Equivalents

$221M

No prior period
Total Assets

$281M

No prior period
Stock-Based Comp

$3.58M

No prior period

Revenue & EPS history

Prime Medicine · Revenue · Quarterly

$1.65M

Q4 2025-44.7%vs Q4 2024
Beat estimate in 0 of 8 quarters(0%)
ActualEstimate

Forward guidance

Prime Medicine expects to initiate investigational new drug (IND)-enabling studies for PM359 in CGD in 2023 and complete first IND filing as early as 2024 with additional IND filings anticipated in 2025.

Tailwinds

  • Initiate investigational new drug (IND)-enabling studies for PM359 in CGD in 2023.
  • Expand preclinical proof-of-concept in vivo data, with plans to share data from in vivo rodent studies and large animal studies from several programs in the second half of 2023.
  • Share in vitro preclinical data in additional liver, eye and neuromuscular programs.
  • Complete first IND filing as early as 2024.
  • Additional IND filings anticipated in 2025.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 14 quarterly earnings reports · overlaid with Q2 2023

Historical avgQ2 2023

-1.7%

Avg return

Earnings day

-7.2%

Avg return

5 days after

-10.8%

Avg return

30 days after

29%

5 / 17 earnings

Positive

+26.6%

Q1 2025

Best reaction

-9.8%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-8.2%-13.9%-28.8%
Q3 2025-9.1%-15.1%-10.5%
Q1 2025+26.6%-7.5%+15.9%
Q4 2024+4.1%-4.5%-17.8%
Q3 2024-9.8%-23.8%-31.4%
Q2 2024-4.5%-2.5%-19.3%
Q1 2024+12.2%+18.2%+14.9%
Q4 2023+1.6%-2.4%-18.9%
Q3 2023+17.0%+13.1%+21.6%
Q2 2023-7.5%-14.9%-13.3%
Q1 2022-9.4%-10.5%+3.2%
Q1 2023-9.4%-10.5%+3.2%
Q4 2020-9.7%-11.7%-21.9%
Q4 2022-9.7%-11.7%-21.9%
Q3 2022-4.4%-8.1%-19.4%
Q3 2021-4.4%-8.1%-19.4%
Q4 2021-4.4%-8.1%-19.4%
Q2 2021
Q1 2021
Q4 2019

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