NASDAQ$PRME

Prime Medicine Inc · Q3 2024 earnings

Q3 2024 earnings · · Investor relations

Briefing

Prime Medicine reported third quarter results, highlighted strategic pipeline prioritization, and announced a research collaboration with Bristol Myers Squibb.

Prime Medicine reported a net loss of $52.5 million for the third quarter of 2024. They received $110 million upfront from Bristol Myers Squibb through a strategic research collaboration. Pro-forma cash, cash equivalents, and investments are expected to fund operations into 1H 2026.

  • Presented initial in vivo data for universal liver-targeted LNP and Wilson’s Disease program at ESGCT.
  • Initiated IND-enabling activities for Wilson’s Disease program in 4Q 2024, on track to file IND and/or CTA in 1H 2026.
  • Announced strategic research collaboration and license agreement with Bristol Myers Squibb; received $110 million upfront, with potential for more than $3.5 billion in milestone payments.
  • On track to report initial data from Phase 1/2 clinical trial of PM359 for p47phox CGD in 2025.

Headline financials

Total Revenue

$209K

Previous: $0.00
EPS

-$0.44

Previous: -$0.55+20.0%
R&D Expenses

$40.3M

No prior period
G&A Expenses

$14.1M

No prior period
Total Operating Expenses

$54.4M

No prior period
Total Liabilities

$144M

No prior period
Total Stockholders' Equity

$153M

No prior period
Capital Expenditures

-$5.5M

Previous: $2.91M-289.2%
Free Cash Flow

-$58M

Previous: -$42.1M-37.9%
Net Income

-$52.5M

Previous: -$50.7M-3.6%
Operating Income

-$54.2M

Previous: -$51.5M-5.4%
R&D Expense

$40.3M

Previous: $41M-1.5%
Stock-Based Comp

$6.83M

Previous: $4.22M+61.9%

Revenue & EPS history

Prime Medicine · Revenue · Quarterly

$209K

Q3 2024
Beat estimate in 0 of 8 quarters(0%)
ActualEstimate

Forward guidance

Prime Medicine expects that its pro-forma cash, cash equivalents and investments as of September 30, 2024 will be sufficient to fund its operating expenses and capital expenditure requirements into the first half of 2026.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 14 quarterly earnings reports · overlaid with Q3 2024

Historical avgQ3 2024

-1.7%

Avg return

Earnings day

-7.2%

Avg return

5 days after

-10.8%

Avg return

30 days after

29%

5 / 17 earnings

Positive

+26.6%

Q1 2025

Best reaction

-9.8%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-8.2%-13.9%-28.8%
Q3 2025-9.1%-15.1%-10.5%
Q1 2025+26.6%-7.5%+15.9%
Q4 2024+4.1%-4.5%-17.8%
Q3 2024-9.8%-23.8%-31.4%
Q2 2024-4.5%-2.5%-19.3%
Q1 2024+12.2%+18.2%+14.9%
Q4 2023+1.6%-2.4%-18.9%
Q3 2023+17.0%+13.1%+21.6%
Q2 2023-7.5%-14.9%-13.3%
Q1 2022-9.4%-10.5%+3.2%
Q1 2023-9.4%-10.5%+3.2%
Q4 2020-9.7%-11.7%-21.9%
Q4 2022-9.7%-11.7%-21.9%
Q3 2022-4.4%-8.1%-19.4%
Q3 2021-4.4%-8.1%-19.4%
Q4 2021-4.4%-8.1%-19.4%
Q2 2021
Q1 2021
Q4 2019

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