NASDAQ$OLMA

Olema Pharmaceuticals Inc · Q2 2021 earnings

Q2 2021 earnings · · Investor relations

Briefing

Olema Oncology reported financial results for the second quarter of 2021 and provided a corporate update.

Olema Oncology reported a net loss of $16.4 million for the second quarter of 2021. The company's cash, cash equivalents, and marketable securities totaled $318.1 million as of June 30, 2021, expected to fund operations through the end of 2023.

  • Advanced the Phase 1/2 clinical trial of OP-1250 in patients with metastatic, ER+ / HER2- breast cancer, enrolling 28 patients across five dose-escalation cohorts as of June 4, 2021.
  • OP-1250 demonstrated oral bioavailability and a dose-proportional pharmacokinetic profile.
  • Interim safety, tolerability, pharmacokinetic, and initial efficacy data presentation planned for Q4 2021.
  • Cash, cash equivalents and marketable securities as of June 30, 2021 were $318.1 million, anticipated to fund operations through the end of 2023.

Headline financials

EPS (adj)

-$0.42

Previous: -$1.60+73.8%
Capital Expenditures

$360K

Previous: $6K+5900.0%
Free Cash Flow

-$9.27M

Previous: -$1.19M-680.5%
Net Income

-$16.4M

Previous: -$2.45M-568.8%
Operating Income

-$16.5M

Previous: -$2.49M-564.6%
Cash & Equivalents

$318M

Previous: $50.5M+530.2%
Total Assets

$322M

No prior period
Stock-Based Comp

$3.92M

Previous: $154K+2446.1%

Revenue & EPS history

Olema · Revenue · Quarterly

$0

Q3 2025

Forward guidance

Olema Oncology anticipates presenting preliminary Phase 1/2 dose-escalation data for OP-1250 in patients with metastatic, ER+ / HER2- breast cancer in Q4 2021. The company expects its cash balance to be sufficient to fund operations through the end of 2023.

Tailwinds

  • Presentation of preliminary Phase 1/2 dose-escalation data for OP-1250 in patients with metastatic, ER+ / HER2- breast cancer planned for Q4 2021.
  • Advancement into monotherapy dose expansion in the second half of 2021.
  • Initiation of a Phase 1b clinical trial of OP-1250 in combination with a CDK4/6 inhibitor in the first quarter of 2022.
  • OP-1250 has demonstrated oral bioavailability.
  • A maximum tolerated dose has not been identified.

Headwinds

  • The risk that Olema’s ongoing or future clinical studies in humans may show that OP-1250 is not a tolerable and effective treatment for breast cancer
  • Olema's Quarterly Report on Form 10-Q for the quarter ended June 30, 2021 to be filed on August 10, 2021
  • Various risks and uncertainties, and actual results, performance or achievements of Olema could differ materially from those described in or implied by the statements in this press release.
  • Olema is a clinical-stage biopharmaceutical company
  • Net loss for the quarter ended June 30, 2021 was $16.4 million

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q2 2021

Historical avgQ2 2021

-0.1%

Avg return

Earnings day

-2.4%

Avg return

5 days after

+7.5%

Avg return

30 days after

52%

12 / 23 earnings

Positive

+17.0%

Q4 2021

Best reaction

-28.5%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-3.2%-7.7%-29.4%
Q3 2025+4.1%+0.6%+267.4%
Q2 2025+16.0%+20.6%+75.1%
Q1 2025+2.1%+9.6%-11.0%
Q4 2024-8.5%+4.3%+6.8%
Q3 2024-9.7%-27.9%-47.2%
Q1 2024-12.5%-18.0%+16.8%
Q4 2023-6.6%-11.2%-15.8%
Q3 2023-7.6%-7.4%-29.2%
Q2 2023+15.3%+14.0%+24.7%
Q1 2023+1.1%+6.1%-0.3%
Q4 2022+0.0%+0.3%-15.4%
Q3 2022-7.2%+5.6%-22.5%
Q2 2022-28.5%-29.4%-23.1%
Q1 2022-1.3%-3.1%+79.4%
Q4 2019+17.0%-2.2%-5.9%
Q4 2021+17.0%-2.2%-5.9%
Q3 2021+1.1%-1.9%-61.9%
Q3 2020+1.1%-1.9%-61.9%
Q2 2020+3.4%+1.9%+11.2%
Q2 2021+3.4%+1.9%+11.2%
Q1 2021+11.9%+14.8%+35.8%
Q4 2020-10.2%-23.2%-27.2%
Q1 2020

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