NASDAQ$OLMA

Olema Pharmaceuticals Inc · Q4 2026 earnings

Q4 2026 earnings · · After market close · Investor relations

Briefing

Olema reported Q4 fiscal 2026 net loss of $53.1M with no product revenue.

For the quarter ended March 31, 2026 (fiscal Q4 2026), Olema Pharmaceuticals reported a net loss of $53.1 million versus $30.4 million in the prior-year quarter, with no product revenue as palazestrant and other breast cancer programs continue in clinical trials.

  • Net loss $53.1M, up from $30.4M YoY.
  • Clinical-stage breast oncology focus.
  • Higher R&D on pivotal programs.
  • Cash position in balance sheet notes.

Headline financials

EPS (adj)

-$0.52

No prior period
Net Income

-$53.1M

No prior period
Operating Income

-$58M

No prior period

Revenue & EPS history

Olema · Revenue · Quarterly

$0

Q3 2025

Forward guidance

Clinical readouts and regulatory path will drive outlook; no revenue guidance.

Tailwinds

  • Lead assets in large oncology market.
  • Potential partnership economics.

Headwinds

  • Rising losses on trial expansion.
  • Binary clinical/regulatory risk.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2026

Historical avgQ4 2026

-0.1%

Avg return

Earnings day

-2.4%

Avg return

5 days after

+7.5%

Avg return

30 days after

52%

12 / 23 earnings

Positive

+17.0%

Q4 2021

Best reaction

-28.5%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-3.2%-7.7%-29.4%
Q3 2025+4.1%+0.6%+267.4%
Q2 2025+16.0%+20.6%+75.1%
Q1 2025+2.1%+9.6%-11.0%
Q4 2024-8.5%+4.3%+6.8%
Q3 2024-9.7%-27.9%-47.2%
Q1 2024-12.5%-18.0%+16.8%
Q4 2023-6.6%-11.2%-15.8%
Q3 2023-7.6%-7.4%-29.2%
Q2 2023+15.3%+14.0%+24.7%
Q1 2023+1.1%+6.1%-0.3%
Q4 2022+0.0%+0.3%-15.4%
Q3 2022-7.2%+5.6%-22.5%
Q2 2022-28.5%-29.4%-23.1%
Q1 2022-1.3%-3.1%+79.4%
Q4 2019+17.0%-2.2%-5.9%
Q4 2021+17.0%-2.2%-5.9%
Q3 2021+1.1%-1.9%-61.9%
Q3 2020+1.1%-1.9%-61.9%
Q2 2020+3.4%+1.9%+11.2%
Q2 2021+3.4%+1.9%+11.2%
Q1 2021+11.9%+14.8%+35.8%
Q4 2020-10.2%-23.2%-27.2%
Q1 2020

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