NASDAQ$IRON

Disc Medicine Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Disc Medicine became publicly traded through reverse merger, strengthened balance sheet, and progressed bitopertin and DISC-0974 into patient studies.

Disc Medicine reported its full year 2022 financial results, highlighting its transformation into a publicly-traded company through a reverse merger with Gemini Therapeutics. The company ended the year with $194.6 million in cash and cash equivalents and advanced its pipeline programs, including bitopertin and DISC-0974, into clinical studies.

  • Completed reverse merger with Gemini Therapeutics, debuting on Nasdaq as “IRON”.
  • Ended 2022 with approximately $194.6 million in cash and cash equivalents.
  • Initiated two Phase 2 trials, AURORA and BEACON, for bitopertin in erythropoietic protoporphyria (EPP).
  • Initiated Phase 1b/2 studies of DISC-0974 in myelofibrosis (MF) patients with anemia and in patients with anemia of chronic kidney disease.

Headline financials

EPS (adj)

-$44.46

Previous: -$39.58-12.3%
Capital Expenditures

$151K

Previous: $10K+1410.0%
Free Cash Flow

-$12.6M

Previous: -$12.7M+1.0%
Net Income

-$46.8M

Previous: -$71.9M+34.8%
Operating Income

-$47.5M

Previous: -$17.7M-167.6%
Cash & Equivalents

$195M

Previous: $137M+42.4%
Total Assets

$200M

Previous: $140M+42.6%
Stock-Based Comp

-$3.18M

Previous: $1.67M-290.3%

Revenue & EPS history

Disc Medicine · Revenue · Quarterly

$0

Q3 2025

Forward guidance

Disc Medicine expects to present interim data from the BEACON study in the first half of 2023 and topline data from the AURORA study by year-end 2023. Interim data from the Phase 1b/2 studies of DISC-0974 in myelofibrosis and NDD-CKD patients are expected by the end of 2023. The company anticipates these combined cash and cash equivalents to fund its operational plans into 2025.

Tailwinds

  • Interim data from BEACON study expected in 1H 2023.
  • Topline data from AURORA study expected by year-end 2023.
  • Interim data from DISC-0974 Phase 1b/2 studies expected by year-end 2023.
  • Initiate a Phase 1 study of MWTX-003 in healthy volunteers during the second half of 2023.
  • Cash and cash equivalents expected to fund operational plans into 2025.

Headwinds

  • Difficulty in predicting the time and cost of development of product candidates.
  • Clinical trial results may not be predictive of future results.
  • The company may not be able to identify additional product candidates with significant commercial potential.
  • Adequacy of Disc’s capital to support its future operations and its ability to successfully initiate and complete clinical trials
  • Disc may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

-0.4%

Avg return

Earnings day

-1.7%

Avg return

5 days after

+3.9%

Avg return

30 days after

56%

10 / 18 earnings

Positive

+14.6%

Q3 2021

Best reaction

-12.4%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+1.3%-3.8%-10.2%
Q3 2025-1.6%-2.5%+5.6%
Q2 2025-3.4%+0.1%+3.0%
Q1 2025+2.3%+3.8%+14.1%
Q4 2024+0.1%+1.6%-3.9%
Q3 2024-5.3%-10.7%-3.5%
Q1 2024+3.5%+8.5%+33.3%
Q4 2023-8.7%-9.2%-56.8%
Q3 2023+1.7%+8.1%+27.8%
Q2 2023+0.3%+1.9%-1.2%
Q1 2023+0.6%+1.8%+47.6%
Q4 2022-0.6%+0.7%+48.4%
Q3 2022-0.6%-4.7%-2.4%
Q2 2022-12.4%-10.9%-31.8%
Q1 2022+3.6%+10.1%+8.6%
Q4 2021-3.2%-7.7%-11.0%
Q3 2021+14.6%-5.6%-12.6%
Q2 2021+0.2%-12.8%+15.3%

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