NASDAQ$IRON
Disc Medicine Inc · Q1 2025 earnings
Q1 2025 earnings · · Before market open · Investor relations
Briefing
Disc Medicine reported its first quarter 2025 financial results, highlighting operational progress across its portfolio and a strong financial position.
Disc Medicine reported a net loss of $34.1 million for Q1 2025, an increase from $26.9 million in Q1 2024, primarily due to higher operating costs. The company ended the quarter with $694.7 million in cash, cash equivalents, and marketable securities, expected to fund operations into 2028. Key operational milestones include the initiation of the APOLLO trial for bitopertin in EPP and progress in the DISC-0974 program.
- Net loss for Q1 2025 was $34.1 million, compared to $26.9 million for Q1 2024.
- Cash, cash equivalents, and marketable securities totaled $694.7 million as of March 31, 2025, providing a cash runway into 2028.
- Research and Development expenses increased to $27.8 million in Q1 2025 from $23.7 million in Q1 2024, driven by portfolio progression and drug manufacturing.
- The APOLLO trial for bitopertin in EPP has been initiated, and the company remains on track to submit the NDA for bitopertin in EPP in H2 2025.
Headline financials
Revenue & EPS history
Disc Medicine · Revenue · Quarterly
$0
Forward guidance
Disc Medicine anticipates significant progress in its clinical programs and financial stability, with key data readouts and regulatory submissions expected in the second half of 2025.
Tailwinds
- Company remains on track to submit NDA for bitopertin in EPP in H2 2025 under the accelerated approval pathway.
- Initiated APOLLO, a confirmatory clinical trial of bitopertin in adults and adolescents with EPP, designed to support conversion to full approval.
- Plan to initiate Phase 2 study of DISC-3405 in polycythemia vera (PV) in H1 2025.
- Expect data readouts for DISC-0974 program in H2 2025, including initial results of Phase 2 anemia of myelofibrosis (MF) study and multiple dose data from Phase 1b anemia of non-dialysis dependent chronic kidney disease (NDD-CKD) study.
- Strong financial position supported by $259 million public offering in January 2025; ended Q1 with $695 million in cash, cash equivalents, and marketable securities, which is expected to fund operations into 2028.
Headwinds
- Actual results or events could differ materially from the plans, intentions and expectations disclosed in the forward-looking statements.
- The adequacy of Disc's capital to support its future operations and its ability to successfully initiate and complete clinical trials is subject to risks.
- Difficulty in predicting the time and cost of development of Disc's product candidates.
- The timing of the availability of data from Disc's clinical trials may vary.
- Preclinical study results may not be predictive of future results in connection with future studies or clinical trials and may not support further development and marketing approval.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 18 quarterly earnings reports · overlaid with Q1 2025
-0.4%
Avg return
Earnings day
-1.7%
Avg return
5 days after
+3.9%
Avg return
30 days after
56%
10 / 18 earnings
Positive
+14.6%
Q3 2021
Best reaction
-12.4%
Q2 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2026 | +1.3% | -3.8% | -10.2% | |
| Q3 2025 | -1.6% | -2.5% | +5.6% | |
| Q2 2025 | -3.4% | +0.1% | +3.0% | |
| Q1 2025 | +2.3% | +3.8% | +14.1% | |
| Q4 2024 | +0.1% | +1.6% | -3.9% | |
| Q3 2024 | -5.3% | -10.7% | -3.5% | |
| Q1 2024 | +3.5% | +8.5% | +33.3% | |
| Q4 2023 | -8.7% | -9.2% | -56.8% | |
| Q3 2023 | +1.7% | +8.1% | +27.8% | |
| Q2 2023 | +0.3% | +1.9% | -1.2% | |
| Q1 2023 | +0.6% | +1.8% | +47.6% | |
| Q4 2022 | -0.6% | +0.7% | +48.4% | |
| Q3 2022 | -0.6% | -4.7% | -2.4% | |
| Q2 2022 | -12.4% | -10.9% | -31.8% | |
| Q1 2022 | +3.6% | +10.1% | +8.6% | |
| Q4 2021 | -3.2% | -7.7% | -11.0% | |
| Q3 2021 | +14.6% | -5.6% | -12.6% | |
| Q2 2021 | +0.2% | -12.8% | +15.3% |
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