NASDAQ$IONS

Ionis Pharmaceuticals · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Ionis reported financial results for Q1 2024, highlighting the WAINUA launch and progress in regulatory submissions and clinical data.

Ionis Pharmaceuticals reported its Q1 2024 financial results, featuring total revenues of $119 million. The company saw increased operating expenses due to investments in launching WAINUA, olezarsen, and donidalorsen. They reaffirmed their 2024 financial guidance and have $2.2 billion in cash and short-term investments.

  • WAINUA launch is progressing well, contributing $1 million in royalty revenue.
  • Olezarsen NDA was submitted to the FDA for FCS, with EU regulatory submission preparation underway.
  • Positive Phase 3 donidalorsen data for HAE were reported, with regulatory submissions being prepared.
  • Ionis is on track to achieve its 2024 financial guidance.

Headline financials

Total Revenue

$119M

Previous: $131M-8.4%
EPS

-$0.98

Previous: -$0.68-44.1%
Non-GAAP Operating Expenses

$238M

No prior period
Capital Expenditures

-$4.49M

Previous: -$10.5M+57.1%
Free Cash Flow

-$147M

Previous: -$135M-9.3%
Net Income

-$143M

Previous: -$124M-14.9%
Operating Income

-$150M

Previous: -$114M-31.0%
Gross Profit

$117M

Previous: $129M-9.2%
Cash & Equivalents

$349M

Previous: $309M+12.9%
Total Assets

$2.76B

Previous: $2.89B-4.2%
R&D Expense

$214M

No prior period
Stock-Based Comp

$31.3M

Previous: $26.9M+16.3%

Revenue & EPS history

Ionis · Revenue · Quarterly

$119M

Q1 2024-8.4%vs Q1 2023
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Ionis · $151M total across 2 segments · Q2 2023

  • Collaborative Agreement Rev
    $90M+130.8%
  • SPINRAZA Royalties
    $61M+1.7%

Forward guidance

Ionis reaffirmed its 2024 financial guidance.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+0.2%

Avg return

Earnings day

+1.9%

Avg return

5 days after

+1.2%

Avg return

30 days after

51%

35 / 68 earnings

Positive

+30.2%

Q3 2016

Best reaction

-13.5%

Q3 2011

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.2%+5.1%+6.6%
Q4 2025-5.3%-4.1%-15.6%
Q3 2025-2.3%+0.1%+12.5%
Q1 2025+3.0%+12.9%+12.4%
Q4 2024-0.4%-0.2%+3.0%
Q3 2024-0.9%+0.2%-1.8%
Q2 2024-0.7%-4.9%-3.6%
Q1 2024-5.0%-7.6%-5.7%
Q4 2023-0.8%+3.9%-3.7%
Q3 2023+4.3%+5.4%+14.1%
Q2 2023+0.7%+0.8%+4.2%
Q1 2023+1.3%-1.0%+17.5%
Q4 2022-4.0%-5.3%-11.2%
Q3 2022+7.6%+4.2%-11.2%
Q2 2022+0.9%-3.5%-3.2%
Q1 2022-1.2%-17.6%-6.1%
Q4 2021+3.4%+10.9%+19.3%
Q3 2021+5.0%+5.8%-20.0%
Q2 2021+4.2%+2.0%+4.5%
Q1 2021-11.1%-13.7%-17.7%
Q4 2020-4.7%-3.6%-23.4%
Q3 2020+3.7%+6.6%+9.0%
Q2 2020-4.6%-8.7%-6.1%
Q1 2020-7.7%-2.7%-0.3%
Q4 2019-3.6%-5.4%-10.7%
Q3 2019+1.8%+4.2%+18.8%
Q2 2019+6.6%+6.2%-3.6%
Q1 2019+0.9%-2.8%-7.2%
Q4 2018+15.2%+14.4%+31.7%
Q3 2018+5.4%-0.0%+8.8%
Q2 2018+4.4%+11.6%+1.9%
Q1 2018+7.4%+3.7%+12.9%
Q4 2017+2.8%-4.7%-14.2%
Q3 2017+0.9%+3.0%-0.6%
Q2 2017-8.6%-11.0%+7.4%
Q1 2017-2.6%+3.9%+10.3%
Q4 2016+5.4%+16.6%-13.8%
Q3 2016+30.2%+51.0%+44.9%
Q2 2016+0.1%-2.5%-14.1%
Q1 2016-8.7%
Q4 2015-4.6%
Q3 2015+14.8%
Q2 2015+1.0%
Q1 2015+1.2%
Q4 2014-0.8%
Q3 2014+4.4%
Q2 2014+6.3%
Q1 2014-6.5%
Q4 2013-9.7%
Q3 2013-6.1%
Q2 2013-4.2%
Q1 2013-12.4%
Q4 2012+7.6%
Q3 2012-7.0%
Q2 2012+3.9%
Q1 2012+7.6%
Q4 2011+2.8%
Q3 2011-13.5%
Q2 2011-8.2%
Q1 2010-2.7%
Q1 2011+2.8%
Q4 2008-1.6%
Q4 2010-1.6%
Q3 2009+2.5%
Q3 2010+2.5%
Q4 2009-3.8%
Q2 2010-3.8%
Q2 2009-3.8%

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