NASDAQ$INCY

Incyte Corp. · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Incyte reported strong Q4 2022 financial results, driven by growth in Jakafi and Opzelura sales, and provided 2023 financial guidance.

Incyte reported Q4 2022 total GAAP revenues of $926.7 million, a 7% increase compared to Q4 2021. Jakafi net revenues were $647.5 million, a 9% increase year-over-year. Opzelura net revenues reached $61.3 million, driven by strong demand in atopic dermatitis and vitiligo.

  • Total FY'22 net product revenues grew 18% to $2.75 billion; total FY'22 revenues of $3.4 billion (+14% Y/Y).
  • Jakafi net revenues of $647 million (+9% Y/Y) in Q4'22 and $2.41 billion (+13%) in FY'22.
  • Opzelura net revenues of $61 million in Q4'22 and $129 million in FY'22, driven by strong demand in atopic dermatitis, a successful launch in vitiligo and broadening formulary access.
  • Incyte granted pediatric exclusivity for Jakafi, extending patent expiry through December 2028.

Headline financials

Total Revenue

$927M

Previous: $863M+7.4%
EPS (adj)

$0.62

Previous: $0.10+520.0%
Net Income

$28.5M

Previous: $564M-95.0%
Operating Income

$70.1M

Previous: $111M-36.7%
Gross Profit

$868M

Previous: $819M+5.9%
Cash & Equivalents

$3.24B

Previous: $2.06B+57.4%
Total Assets

$5.84B

Previous: $4.93B+18.4%
Stock-Based Comp

$52.7M

Previous: $48.2M+9.2%

Revenue & EPS history

Incyte · Revenue · Quarterly

$927M

Q4 2022+7.4%vs Q4 2021
Beat estimate in 10 of 15 quarters(67%)
ActualEstimate

Revenue by segment

Incyte · $759M total across 4 segments · Q4 2022

  • Jakafi
    $647M+9.3%
  • Opzelura
    $61.3M+1212.8%
  • Iclusig
    $27.6M+2.1%
  • Pemazyre
    $23M+17.4%

Forward guidance

Incyte provided financial guidance for 2023, which does not include revenue from any potential new product launches or the impact of any potential future strategic transactions.

Tailwinds

  • Jakafi net product revenues: $2.53 - $2.63 billion
  • Other Hematology/Oncology net product revenues: $215 - $225 million
  • GAAP Cost of product revenues: 7 – 8% of net product revenues
  • Non-GAAP Cost of product revenues: 6 – 7% of net product revenues
  • GAAP Research and development expenses: $1,610 - $1,650 million

Headwinds

  • Non-GAAP Research and development expenses: $1,485 - $1,520 million
  • GAAP Selling, general and administrative expenses: $1,050 - $1,150 million
  • Non-GAAP Selling, general and administrative expenses: $965 - $1,060 million
  • Guidance does not include revenue from any potential new product launches
  • Guidance does not include the impact of any potential future strategic transactions.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

+0.3%

Avg return

Earnings day

-1.4%

Avg return

5 days after

+0.6%

Avg return

30 days after

50%

32 / 64 earnings

Positive

+18.2%

Q1 2012

Best reaction

-25.8%

Q2 2012

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.2%+1.2%+0.8%
Q4 2025-8.2%-7.3%-15.6%
Q3 2025-1.6%+0.4%+13.5%
Q1 2025+1.5%+5.1%+11.0%
Q4 2024-7.9%-5.0%-8.6%
Q3 2024+12.5%+15.9%+14.9%
Q2 2024-5.1%-6.0%-3.9%
Q1 2024+0.7%+2.3%+9.0%
Q4 2023+0.1%+0.2%+1.2%
Q3 2023+4.2%+5.2%+4.2%
Q2 2023+3.1%-0.1%+1.3%
Q1 2023-9.7%-11.7%-18.4%
Q4 2022-4.6%-6.0%-13.6%
Q3 2022+3.8%+4.0%+8.5%
Q2 2022-6.3%-6.8%-7.8%
Q1 2022+6.1%-1.1%-1.9%
Q4 2021-6.9%-9.0%+0.2%
Q3 2021-3.7%-2.1%-3.9%
Q2 2021-1.4%-2.8%-1.6%
Q1 2021-5.0%-3.3%-3.1%
Q4 2020-9.0%-9.9%-15.1%
Q3 2020-8.8%-8.9%-8.8%
Q2 2020-4.1%-4.8%-10.0%
Q1 2020-4.9%-5.0%-7.1%
Q4 2019+3.5%+4.6%-2.6%
Q3 2019+4.8%+4.7%+17.9%
Q2 2019+5.8%+4.0%+2.7%
Q1 2019+6.1%+11.7%+5.9%
Q4 2018+3.8%+3.7%+4.6%
Q3 2018+2.4%+6.5%+2.3%
Q2 2018-4.4%-8.1%+7.4%
Q1 2018-1.4%+0.3%+10.2%
Q4 2017-2.4%-3.0%+2.1%
Q3 2017-5.5%-8.0%-13.3%
Q2 2017-5.7%-3.4%+3.1%
Q1 2017-0.6%-2.8%+6.7%
Q4 2016-0.2%-0.5%+22.5%
Q3 2016+0.2%+0.7%+14.9%
Q2 2016-5.2%-7.9%-7.4%
Q1 2016+4.0%
Q4 2015-5.5%
Q3 2015-2.9%
Q2 2015+6.7%
Q1 2015-3.3%
Q4 2014-0.0%
Q3 2014+15.9%
Q2 2014-4.9%
Q1 2014+6.3%
Q4 2013+0.2%
Q3 2013+4.7%
Q2 2013+14.7%
Q1 2013+3.3%
Q4 2012+18.0%
Q3 2012+6.8%
Q2 2012-25.8%
Q1 2012+18.2%
Q4 2011+1.7%
Q3 2010+0.9%
Q3 2011+0.9%
Q2 2010+0.0%
Q2 2011+0.0%
Q4 2010+6.0%
Q1 2010+6.0%
Q1 2011+6.0%

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