NASDAQ$INCY

Incyte Corp. · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Incyte's Q4 2021 earnings were released, highlighting strong revenue growth and progress in key clinical programs.

Incyte reported a 20% increase in total product and royalty revenues to $813 million for Q4 2021, driven by robust demand for Jakafi, continued uptake of Pemazyre, and a rapidly growing royalty revenue stream. The company also saw a successful U.S. launch of Opzelura with nearly 19,000 patients treated since launch.

  • Total product and royalty revenues increased by 20% to $813 million in Q4 2021.
  • Jakafi net product revenues grew by 15% to $592 million in Q4 2021.
  • Successful U.S. launch of Opzelura with nearly 19,000 patients treated from launch through the end of the year.
  • Vitiligo is the next substantial growth opportunity for ruxolitinib cream – under Priority Review in the U.S. and under review in Europe.

Headline financials

Total Revenue

$863M

Previous: $790M+9.3%
EPS (adj)

$0.10

Previous: $0.93-89.2%
Net Income

$564M

Previous: $150M+276.3%
Operating Income

$111M

Previous: $164M-32.6%
Gross Profit

$819M

Previous: $753M+8.7%
Cash & Equivalents

$2.06B

Previous: $1.8B+14.3%
Total Assets

$4.93B

Previous: $3.56B+38.5%
Stock-Based Comp

$48.2M

Previous: $45.3M+6.5%

Revenue & EPS history

Incyte · Revenue · Quarterly

$863M

Q4 2021+9.3%vs Q4 2020
Beat estimate in 11 of 16 quarters(69%)
ActualEstimate

Revenue by segment

Incyte · $644M total across 4 segments · Q4 2021

  • Jakafi
    $592M
  • Iclusig
    $27M
  • Pemazyre
    $19.6M
  • Opzelura
    $4.67M

Forward guidance

Incyte provided financial guidance for 2022, which does not include revenue from Opzelura or the impact of any potential future strategic transactions.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+0.3%

Avg return

Earnings day

-1.4%

Avg return

5 days after

+0.6%

Avg return

30 days after

50%

32 / 64 earnings

Positive

+18.2%

Q1 2012

Best reaction

-25.8%

Q2 2012

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.2%+1.2%+0.8%
Q4 2025-8.2%-7.3%-15.6%
Q3 2025-1.6%+0.4%+13.5%
Q1 2025+1.5%+5.1%+11.0%
Q4 2024-7.9%-5.0%-8.6%
Q3 2024+12.5%+15.9%+14.9%
Q2 2024-5.1%-6.0%-3.9%
Q1 2024+0.7%+2.3%+9.0%
Q4 2023+0.1%+0.2%+1.2%
Q3 2023+4.2%+5.2%+4.2%
Q2 2023+3.1%-0.1%+1.3%
Q1 2023-9.7%-11.7%-18.4%
Q4 2022-4.6%-6.0%-13.6%
Q3 2022+3.8%+4.0%+8.5%
Q2 2022-6.3%-6.8%-7.8%
Q1 2022+6.1%-1.1%-1.9%
Q4 2021-6.9%-9.0%+0.2%
Q3 2021-3.7%-2.1%-3.9%
Q2 2021-1.4%-2.8%-1.6%
Q1 2021-5.0%-3.3%-3.1%
Q4 2020-9.0%-9.9%-15.1%
Q3 2020-8.8%-8.9%-8.8%
Q2 2020-4.1%-4.8%-10.0%
Q1 2020-4.9%-5.0%-7.1%
Q4 2019+3.5%+4.6%-2.6%
Q3 2019+4.8%+4.7%+17.9%
Q2 2019+5.8%+4.0%+2.7%
Q1 2019+6.1%+11.7%+5.9%
Q4 2018+3.8%+3.7%+4.6%
Q3 2018+2.4%+6.5%+2.3%
Q2 2018-4.4%-8.1%+7.4%
Q1 2018-1.4%+0.3%+10.2%
Q4 2017-2.4%-3.0%+2.1%
Q3 2017-5.5%-8.0%-13.3%
Q2 2017-5.7%-3.4%+3.1%
Q1 2017-0.6%-2.8%+6.7%
Q4 2016-0.2%-0.5%+22.5%
Q3 2016+0.2%+0.7%+14.9%
Q2 2016-5.2%-7.9%-7.4%
Q1 2016+4.0%
Q4 2015-5.5%
Q3 2015-2.9%
Q2 2015+6.7%
Q1 2015-3.3%
Q4 2014-0.0%
Q3 2014+15.9%
Q2 2014-4.9%
Q1 2014+6.3%
Q4 2013+0.2%
Q3 2013+4.7%
Q2 2013+14.7%
Q1 2013+3.3%
Q4 2012+18.0%
Q3 2012+6.8%
Q2 2012-25.8%
Q1 2012+18.2%
Q4 2011+1.7%
Q3 2010+0.9%
Q3 2011+0.9%
Q2 2010+0.0%
Q2 2011+0.0%
Q4 2010+6.0%
Q1 2010+6.0%
Q1 2011+6.0%

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