NASDAQ$GH

Guardant Health Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Guardant Health reported strong revenue growth and increased testing volumes in Q4 2024.

Guardant Health reported Q4 2024 revenue of $201.8 million, a 30% year-over-year increase, driven by strong growth in precision oncology testing. The company reduced net loss compared to the prior year and continued to expand its product portfolio and partnerships.

  • Total revenue increased by 30% to $201.8 million.
  • Precision oncology testing revenue rose by 30% to $184.6 million.
  • Non-GAAP net loss per share improved to $0.62 from $0.64 last year.
  • Shield screening tests generated $4.1 million in revenue.

Headline financials

Total Revenue

$202M

Previous: $155M+30.1%
EPS (adj)

-$0.62

Previous: -$0.64+3.1%
Shield Screening Test Volume

6.4K

No prior period
Non-GAAP Gross Margin

63.0%

No prior period
GAAP Gross Margin

62.0%

No prior period
Net Income

-$111M

Previous: -$187M+40.6%
Operating Income

-$126M

Previous: -$198M+36.2%
Gross Profit

$124M

Previous: $92.5M+34.3%

Revenue & EPS history

Guardant Health · Revenue · Quarterly

$202M

Q4 2024+30.1%vs Q4 2023
Beat estimate in 14 of 15 quarters(93%)
ActualEstimate

Revenue by segment

Guardant Health · $133M total across 1 segment · Q3 2023

  • Oncology Revenue
    $133M+30.7%

Forward guidance

Guardant Health expects FY 2025 revenue to be between $850 million and $860 million, representing a 15-16% increase year-over-year.

Tailwinds

  • Oncology revenue projected to grow approximately 15%.
  • Oncology clinical volume expected to accelerate to 25% growth.
  • Screening revenue forecasted between $25 million and $30 million.
  • Non-GAAP gross margin expected in the range of 62-63%.
  • Free cash flow burn projected to improve to $225-235 million.

Headwinds

  • Increased expenses due to Shield commercial ramp-up.
  • Operating expenses expected to rise by 8-9% in 2025.
  • Continued net losses expected despite revenue growth.
  • Screening segment expected to have $200 million in net cash burn.
  • Market uncertainties may impact reimbursement rates.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+3.8%

Avg return

Earnings day

+2.6%

Avg return

5 days after

+3.9%

Avg return

30 days after

60%

18 / 30 earnings

Positive

+41.3%

Q4 2018

Best reaction

-30.0%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.3%+6.6%+36.1%
Q4 2025-3.0%-10.4%-19.9%
Q3 2025+28.5%+35.8%+50.0%
Q1 2025+3.5%-11.2%-14.0%
Q4 2024-9.6%-8.9%-2.7%
Q3 2024+21.6%+24.8%+56.8%
Q2 2024-5.9%-5.3%-26.2%
Q1 2024+20.0%+32.7%+53.8%
Q4 2023-14.3%-13.8%-23.9%
Q3 2023-8.5%-24.7%-10.2%
Q2 2023+4.6%+1.9%-3.1%
Q1 2023+17.2%+12.1%+38.5%
Q4 2022+4.4%+11.7%-12.6%
Q3 2022+3.3%-3.1%+17.5%
Q2 2022+1.6%-6.0%+2.0%
Q1 2022-30.0%-44.3%-32.3%
Q4 2021+6.0%+7.0%-4.3%
Q3 2021-3.8%-5.8%-20.8%
Q2 2021+0.2%-7.7%+15.7%
Q1 2021-3.1%-14.0%-15.8%
Q4 2020-6.7%-5.0%-15.3%
Q3 2020-0.4%-1.1%+9.0%
Q2 2020+0.6%-4.0%+6.8%
Q1 2020+9.0%+19.6%+2.9%
Q4 2019-14.7%-2.1%-25.9%
Q3 2019+11.2%+13.8%+14.4%
Q2 2019+25.8%+18.2%-5.2%
Q1 2019+17.4%+12.0%+40.3%
Q4 2018+41.3%+46.6%+7.9%
Q3 2018-6.7%+3.1%-2.7%
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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