NASDAQ$GH

Guardant Health Inc · Q1 2026 earnings

Q1 2026 earnings · · After market close · Investor relations

Briefing

Guardant Health reported Q1 2026 revenue of $301.7M (+48% YoY) with a net loss of $112.1M, or $0.85 per diluted share.

For the quarter ended March 31, 2026, Guardant Health generated revenue of $301.7 million versus $203.5 million a year ago, reflecting continued growth in precision oncology testing. The company reported a net loss of $112.1 million, or $0.85 per diluted share, compared with a net loss of $95.2 million, or $0.77 per share, in Q1 2025. Loss from operations widened to $121.4 million as sales and marketing and R&D spending increased with scale.

  • Revenue of $301.7M (+48% YoY) on higher testing volumes across oncology products.
  • Net loss of $112.1M versus $95.2M; diluted EPS $(0.85) versus $(0.77).
  • Loss from operations of $121.4M as operating expenses rose to $423.0M.
  • Cash and investments remained substantial at roughly $1.1B at quarter end.

Headline financials

Total Revenue

$302M

Previous: $203M+48.3%
EPS (adj)

-$0.85

Previous: -$0.77-10.4%
Capital Expenditures

-$5.58M

Previous: -$4.46M-25.1%
Net Income

-$112M

Previous: -$95.2M-17.8%
Operating Income

-$121M

Previous: -$111M-9.3%

Revenue & EPS history

Guardant Health · Revenue · Quarterly

$302M

Q1 2026+48.3%vs Q1 2025
Beat estimate in 14 of 15 quarters(93%)
ActualEstimate

Revenue by segment

Guardant Health · $133M total across 1 segment · Q3 2023

  • Oncology Revenue
    $133M+30.7%

Forward guidance

The 10-Q does not provide quantitative revenue or EPS guidance. Management discusses pipeline expansion, reimbursement progress, and continued investment in R&D and commercial infrastructure.

Tailwinds

  • Revenue growth accelerated to 48% YoY on strong testing demand.
  • Large cash balance supports continued product development and commercial expansion.

Headwinds

  • Operating losses widened with higher R&D and sales and marketing spend.
  • No near-term profitability guidance; path to breakeven depends on volume and reimbursement.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+3.8%

Avg return

Earnings day

+2.6%

Avg return

5 days after

+3.9%

Avg return

30 days after

60%

18 / 30 earnings

Positive

+41.3%

Q4 2018

Best reaction

-30.0%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.3%+6.6%+36.1%
Q4 2025-3.0%-10.4%-19.9%
Q3 2025+28.5%+35.8%+50.0%
Q1 2025+3.5%-11.2%-14.0%
Q4 2024-9.6%-8.9%-2.7%
Q3 2024+21.6%+24.8%+56.8%
Q2 2024-5.9%-5.3%-26.2%
Q1 2024+20.0%+32.7%+53.8%
Q4 2023-14.3%-13.8%-23.9%
Q3 2023-8.5%-24.7%-10.2%
Q2 2023+4.6%+1.9%-3.1%
Q1 2023+17.2%+12.1%+38.5%
Q4 2022+4.4%+11.7%-12.6%
Q3 2022+3.3%-3.1%+17.5%
Q2 2022+1.6%-6.0%+2.0%
Q1 2022-30.0%-44.3%-32.3%
Q4 2021+6.0%+7.0%-4.3%
Q3 2021-3.8%-5.8%-20.8%
Q2 2021+0.2%-7.7%+15.7%
Q1 2021-3.1%-14.0%-15.8%
Q4 2020-6.7%-5.0%-15.3%
Q3 2020-0.4%-1.1%+9.0%
Q2 2020+0.6%-4.0%+6.8%
Q1 2020+9.0%+19.6%+2.9%
Q4 2019-14.7%-2.1%-25.9%
Q3 2019+11.2%+13.8%+14.4%
Q2 2019+25.8%+18.2%-5.2%
Q1 2019+17.4%+12.0%+40.3%
Q4 2018+41.3%+46.6%+7.9%
Q3 2018-6.7%+3.1%-2.7%
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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