NASDAQ$FULC

Fulcrum Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Provided a business update and reported financial results for the fourth quarter and full year of 2021.

Fulcrum Therapeutics reported collaboration revenue of $5.1 million for the fourth quarter of 2021, compared to $4.2 million for the fourth quarter of 2020. Research and development expenses were $18.9 million for the fourth quarter of 2021, as compared to $16.1 million for the fourth quarter of 2020. General and administrative expenses were $9.7 million for the fourth quarter of 2021, as compared to $5.9 million for the fourth quarter of 2020. Net loss was $23.5 million for the fourth quarter of 2021, as compared to a net loss of $17.7 million for the fourth quarter of 2020.

  • Clear path forward for Phase 3 REACH trial with losmapimod in FSHD; Trial expected to begin in 2Q 2022
  • On track to report initial data from Phase 1b trial with FTX-6058 in sickle cell disease in 2Q 2022
  • Engaged with U.S. and EU regulatory agencies, including the Food and Drug Administration (FDA), and gained alignment on key aspects of the design for a Phase 3 trial with losmapimod for FSHD.
  • Appointed Esther Rajavelu Fulcrum’s Chief Financial Officer in January 2022.

Headline financials

Total Revenue

$5.06M

Previous: $4.23M+19.7%
EPS (adj)

-$0.58

Previous: -$0.64+9.4%
Capital Expenditures

$519K

Previous: $472K+10.0%
Free Cash Flow

-$22.4M

Previous: -$20.3M-10.2%
Net Income

-$23.5M

Previous: -$17.7M-32.5%
Operating Income

-$23.6M

Previous: -$17.8M-32.5%
Gross Profit

$4.44M

Previous: -$14.6M+130.3%
Cash & Equivalents

$218M

Previous: $113M+93.2%
Total Assets

$235M

Previous: $130M+81.4%
Stock-Based Comp

$3.79M

Previous: $1.68M+126.2%

Revenue & EPS history

Fulcrum Therapeutics · Revenue · Quarterly

$5.06M

Q4 2021+19.7%vs Q4 2020
Beat estimate in 9 of 16 quarters(56%)
ActualEstimate

Forward guidance

Based on current plans, the company expects that its existing cash, cash equivalents, and marketable securities will be sufficient to enable it to fund its operating expenses and capital expenditure requirements into 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+5.2%

Avg return

Earnings day

+6.3%

Avg return

5 days after

+12.3%

Avg return

30 days after

62%

16 / 26 earnings

Positive

+142.5%

Q2 2021

Best reaction

-54.6%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-21.1%-23.0%-36.3%
Q3 2025-6.6%-9.8%+9.4%
Q1 2025+13.8%+39.0%+78.6%
Q4 2024+0.0%-3.0%-16.5%
Q3 2024-8.8%-16.8%+8.8%
Q2 2024+7.1%+0.6%+1.7%
Q1 2024+5.9%+1.1%+3.2%
Q4 2023+6.1%+12.9%-3.0%
Q3 2023+16.2%-2.5%+38.2%
Q2 2023+3.4%+5.5%+49.7%
Q1 2023+16.2%-0.6%-7.6%
Q4 2022-28.0%-36.6%-62.0%
Q3 2022+23.9%+27.3%+9.4%
Q2 2022+8.4%-6.2%+7.1%
Q1 2022-12.5%-4.1%-3.8%
Q4 2021+17.4%+37.8%+113.9%
Q3 2021-2.3%-4.9%-31.5%
Q2 2021+142.5%+175.3%+233.9%
Q1 2021+4.1%+3.7%-13.2%
Q4 2020-17.7%-17.4%-17.8%
Q3 2020+8.6%+16.9%+22.3%
Q2 2020-54.6%-55.5%-54.7%
Q1 2020+7.9%+18.9%+16.5%
Q4 2019-2.2%-27.8%-49.4%
Q3 2019+1.3%+27.7%+48.9%
Q2 2019+7.2%+6.1%-25.5%
Q4 2018
Q3 2018
Q2 2018
Q1 2018
Q4 2017

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