NASDAQ$FULC

Fulcrum Therapeutics Inc · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Fulcrum Therapeutics reported financial results for the first quarter of 2024 and provided a business update.

Fulcrum Therapeutics reported its Q1 2024 financial results, highlighting a collaboration agreement with Sanofi for losmapimod, progress in the Phase 3 REACH trial for FSHD, and the appointment of Patrick Horn as Chief Medical Officer. The company's cash position was $213.3 million as of March 31, 2024, with a pro forma cash position of $293.3 million including the Sanofi upfront payment.

  • Entered into a collaboration and license agreement with Sanofi for losmapimod development and commercialization outside the U.S.
  • On track to report topline data for the Phase 3 REACH trial of losmapimod in FSHD in the fourth quarter of 2024.
  • Appointed Patrick Horn as Chief Medical Officer.
  • Cash, cash equivalents, and marketable securities were $213.3 million as of March 31, 2024, with a pro forma amount of $293.3 million inclusive of the Sanofi upfront payment.

Headline financials

Total Revenue

$0.00

Previous: $295K-100.0%
EPS (adj)

-$0.43

Previous: -$0.41-4.9%
Capital Expenditures

-$28K

Previous: -$171K+83.6%
Free Cash Flow

-$26.9M

Previous: -$25M-7.8%
Net Income

-$26.9M

Previous: -$24.8M-8.4%
Operating Income

-$29.8M

Previous: -$27.9M-6.8%
Gross Profit

$0.00

Previous: -$271K+100.0%
R&D Expense

$19.8M

No prior period
Stock-Based Comp

$3.92M

Previous: $4.25M-7.9%

Revenue & EPS history

Fulcrum Therapeutics · Revenue · Quarterly

$0

Q1 2024-100%vs Q1 2023
Beat estimate in 4 of 10 quarters(40%)
ActualEstimate

Forward guidance

Based on current operating plans, Fulcrum expects that its cash, cash equivalents, and marketable securities as of March 31, 2024, together with the $80.0 million upfront payment to be received from Sanofi, will be sufficient to fund its operating requirements into 2027.

Tailwinds

  • Cash runway extended into 2027.
  • Upfront payment of $80.0 million from Sanofi.
  • Potential for additional $975.0 million in regulatory and sales-based milestones from Sanofi.
  • Tiered royalties starting in the low-teens of annual net sales of losmapimod outside the U.S. from Sanofi.
  • Global development costs will be equally shared between Fulcrum and Sanofi.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+5.2%

Avg return

Earnings day

+6.3%

Avg return

5 days after

+12.3%

Avg return

30 days after

62%

16 / 26 earnings

Positive

+142.5%

Q2 2021

Best reaction

-54.6%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-21.1%-23.0%-36.3%
Q3 2025-6.6%-9.8%+9.4%
Q1 2025+13.8%+39.0%+78.6%
Q4 2024+0.0%-3.0%-16.5%
Q3 2024-8.8%-16.8%+8.8%
Q2 2024+7.1%+0.6%+1.7%
Q1 2024+5.9%+1.1%+3.2%
Q4 2023+6.1%+12.9%-3.0%
Q3 2023+16.2%-2.5%+38.2%
Q2 2023+3.4%+5.5%+49.7%
Q1 2023+16.2%-0.6%-7.6%
Q4 2022-28.0%-36.6%-62.0%
Q3 2022+23.9%+27.3%+9.4%
Q2 2022+8.4%-6.2%+7.1%
Q1 2022-12.5%-4.1%-3.8%
Q4 2021+17.4%+37.8%+113.9%
Q3 2021-2.3%-4.9%-31.5%
Q2 2021+142.5%+175.3%+233.9%
Q1 2021+4.1%+3.7%-13.2%
Q4 2020-17.7%-17.4%-17.8%
Q3 2020+8.6%+16.9%+22.3%
Q2 2020-54.6%-55.5%-54.7%
Q1 2020+7.9%+18.9%+16.5%
Q4 2019-2.2%-27.8%-49.4%
Q3 2019+1.3%+27.7%+48.9%
Q2 2019+7.2%+6.1%-25.5%
Q4 2018
Q3 2018
Q2 2018
Q1 2018
Q4 2017

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