NASDAQ$FULC

Fulcrum Therapeutics Inc · Q3 2024 earnings

Q3 2024 earnings · · Investor relations

Briefing

Announced third quarter 2024 financial results and business highlights.

Fulcrum Therapeutics reported a net loss of $21.7 million for the third quarter of 2024. The company's cash, cash equivalents, and marketable securities totaled $257.2 million as of September 30, 2024, and they anticipate that the cash will be sufficient to fund operating requirements into at least 2027.

  • Patient enrollment and site activation are progressing in the Phase 1b PIONEER trial of pociredir in sickle cell disease (SCD).
  • Fulcrum plans to initiate Phase 1 clinical studies in healthy volunteers in support of the overall pociredir development program.
  • Fulcrum suspended development of losmapimod and has focused its research and development activities on advancing pociredir for the treatment of SCD.
  • Ended the third quarter of 2024 with $257.2 million in cash, cash equivalents, and marketable securities; cash runway into at least 2027.

Headline financials

Total Revenue

$0.00

Previous: $759K-100.0%
EPS

-$0.35

Previous: -$0.39+10.3%
Capital Expenditures

-$47K

Previous: -$431K+89.1%
Free Cash Flow

-$21.7M

Previous: -$24.4M+11.1%
Net Income

-$21.7M

Previous: -$24M+9.7%
Operating Income

-$25.1M

Previous: -$27.4M+8.4%
R&D Expense

$14.2M

Previous: $17.7M-19.7%
Stock-Based Comp

$3.82M

Previous: $3.74M+2.1%

Revenue & EPS history

Fulcrum Therapeutics · Revenue · Quarterly

$0

Q3 2024-100%vs Q3 2023
Beat estimate in 4 of 10 quarters(40%)
ActualEstimate

Forward guidance

Fulcrum expects to end 2024 with approximately $240.0 million of cash, cash equivalents, and marketable securities and expects its cash burn for the full year 2025 will be approximately $55.0 million to $65.0 million. Fulcrum also expects that its cash, cash equivalents, and marketable securities as of September 30, 2024 will be sufficient to fund its current operating requirements into at least 2027.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2024

Historical avgQ3 2024

+5.2%

Avg return

Earnings day

+6.3%

Avg return

5 days after

+12.3%

Avg return

30 days after

62%

16 / 26 earnings

Positive

+142.5%

Q2 2021

Best reaction

-54.6%

Q2 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-21.1%-23.0%-36.3%
Q3 2025-6.6%-9.8%+9.4%
Q1 2025+13.8%+39.0%+78.6%
Q4 2024+0.0%-3.0%-16.5%
Q3 2024-8.8%-16.8%+8.8%
Q2 2024+7.1%+0.6%+1.7%
Q1 2024+5.9%+1.1%+3.2%
Q4 2023+6.1%+12.9%-3.0%
Q3 2023+16.2%-2.5%+38.2%
Q2 2023+3.4%+5.5%+49.7%
Q1 2023+16.2%-0.6%-7.6%
Q4 2022-28.0%-36.6%-62.0%
Q3 2022+23.9%+27.3%+9.4%
Q2 2022+8.4%-6.2%+7.1%
Q1 2022-12.5%-4.1%-3.8%
Q4 2021+17.4%+37.8%+113.9%
Q3 2021-2.3%-4.9%-31.5%
Q2 2021+142.5%+175.3%+233.9%
Q1 2021+4.1%+3.7%-13.2%
Q4 2020-17.7%-17.4%-17.8%
Q3 2020+8.6%+16.9%+22.3%
Q2 2020-54.6%-55.5%-54.7%
Q1 2020+7.9%+18.9%+16.5%
Q4 2019-2.2%-27.8%-49.4%
Q3 2019+1.3%+27.7%+48.9%
Q2 2019+7.2%+6.1%-25.5%
Q4 2018
Q3 2018
Q2 2018
Q1 2018
Q4 2017

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