NASDAQ$FDMT
4D Molecular Therapeutics Inc · Q2 2024 earnings
Q2 2024 earnings · · Investor relations
Briefing
Reported second quarter 2024 financial results and provided operational highlights.
4DMT reported second quarter 2024 financial results, highlighting positive interim results from the Phase 2 PRISM clinical trial for 4D-150 in wet AMD, strengthened senior leadership, and $578 million in cash and equivalents as of June 30, 2024.
- Announced positive interim results from the Population Extension cohort of the Phase 2 PRISM clinical trial for 4D-150 in a broad wet age-related macular degeneration (wet AMD) population, affirming favorable safety profile and robust clinical activity
- Strengthened senior leadership team and announced formation of a world class Ophthalmology Advisory Board to drive late-stage development of 4D-150 in wet AMD and diabetic eye diseases
- PRISM Phase 1/2 interim data are expected to be presented at the 24th EURETINA Congress on September 19, 2024
- U.S. Food and Drug Administration (FDA) removed clinical hold on the Phase 1/2 INGLAXA study for 4D-310 in Fabry disease cardiomyopathy; enrollment expected to resume in H2 2024
Headline financials
Revenue & EPS history
4DMT · Revenue · Quarterly
$5K
Revenue by segment
4DMT · $20.2M total across 1 segment · Q3 2023
- Collaboration & license rev.$20.2M+3940.8%100.0%
Forward guidance
4DMT anticipates several milestones, including presenting interim data from the PRISM clinical trial at the EURETINA Congress in September 2024, initiating the first Phase 3 clinical trial for 4D-150 in wet AMD in Q1 2025, and providing interim data from the SPECTRA Phase 2 trial in Q4 2024.
Tailwinds
- Interim longest available follow up data up to 2.5 years from its Phase 1/2 PRISM clinical trial evaluating intravitreal 4D-150 in wet AMD are expected to be presented at the 24thEURETINA Congress on September 19, 2024
- 52-week landmark analyses for both 1) severe disease activity (Dose Expansion) & 2) broad wet AMD disease activity (Population Extension) cohorts of PRISM expected in February 2025
- First Phase 3 clinical trial initiation expected in Q1 2025
- Interim data from SPECTRA Phase 2 Part 1 Dose Confirmation cohort (n=22) expected in Q4 2024
- Phase 1 enrollment for 4D-175 is expected to begin in H2 2024
Headwinds
- Interim data update from AEROW clinical trial is expected in mid-2025
- Phase 3 initiation for 4D-710 is expected in H2 2025
- Program update for 4D-725 is expected in Q4 2024
- Resume enrollment in H2 2024 with program update expected in 2025 for 4D-310
- Program updates expected in Q4 2024 for 4D-110 and 4D-125
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q2 2024
+1.0%
Avg return
Earnings day
+2.5%
Avg return
5 days after
+8.5%
Avg return
30 days after
45%
9 / 20 earnings
Positive
+20.0%
Q3 2022
Best reaction
-10.4%
Q2 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -4.6% | -0.7% | -17.3% | |
| Q4 2025 | +7.3% | +7.2% | +22.5% | |
| Q3 2025 | +6.7% | +6.1% | +7.4% | |
| Q1 2025 | +9.9% | +4.7% | +27.0% | |
| Q4 2024 | -8.6% | -8.6% | -28.7% | |
| Q3 2024 | +1.9% | +5.7% | -17.4% | |
| Q2 2024 | +0.6% | +1.6% | +2.4% | |
| Q1 2024 | -2.4% | -2.2% | -13.7% | |
| Q4 2023 | +5.3% | -3.0% | +14.2% | |
| Q3 2023 | +1.8% | +2.2% | +37.7% | |
| Q2 2023 | -1.6% | -1.1% | -7.4% | |
| Q1 2023 | -2.5% | +2.8% | +26.8% | |
| Q4 2022 | -0.7% | -5.4% | -12.5% | |
| Q3 2022 | +20.0% | +66.3% | +188.5% | |
| Q2 2022 | -10.4% | -12.5% | -14.9% | |
| Q1 2022 | -3.1% | -12.9% | -31.5% | |
| Q4 2021 | +8.1% | +1.6% | -22.5% | |
| Q3 2021 | -0.7% | -3.8% | -12.1% | |
| Q2 2021 | -4.0% | +5.2% | +19.4% | |
| Q1 2021 | -3.9% | -3.4% | +2.6% | |
| Q2 2020 | — | — | — | |
| Q4 2019 | — | — | — | |
| Q3 2019 | — | — | — | |
| Q2 2019 | — | — | — | |
| Q4 2018 | — | — | — | |
| Q3 2018 | — | — | — | |
| Q2 2018 | — | — | — |
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