NASDAQ$FDMT

4D Molecular Therapeutics Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

4D Molecular Therapeutics reported Q1 2026 collaboration revenue of $3.0M and a net loss of $68.8M ($1.01 per share).

4DMT recognized $3.0 million of collaboration revenue in Q1 2026 versus $0.01 million and reported a net loss of $68.8 million, or $1.01 per share, compared with $48.0 million and $0.71. R&D spending rose to $65.0 million as gene-therapy trials progressed.

  • Collaboration revenue $3.0M.
  • Net loss $(68.8)M; diluted EPS $(1.01).
  • R&D $65.0M (+60% YoY).
  • Gene-therapy platform for ophthalmology and other indications.
  • Cash runway critical for clinical milestones.

Headline financials

Total Revenue

$3.05M

Previous: $14K+21664.3%
EPS (adj)

-$1.01

Previous: -$0.86-17.4%
Net Income

-$68.8M

Previous: -$48M-43.3%

Revenue & EPS history

4DMT · Revenue · Quarterly

$3.05M

Q1 2026+21,664.3%vs Q1 2025
Beat estimate in 2 of 14 quarters(14%)
ActualEstimate

Revenue by segment

4DMT · $20.2M total across 1 segment · Q3 2023

  • Collaboration & license rev.
    $20.2M+3940.8%

Forward guidance

Pre-revenue gene-therapy biotech; catalysts are trial data and partnerships, not EPS guidance.

Tailwinds

  • Collaboration inflows support operations.
  • Pipeline breadth across therapeutic areas.

Headwinds

  • High cash burn on clinical programs.
  • Regulatory and manufacturing scale-up risk.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+1.0%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+8.5%

Avg return

30 days after

45%

9 / 20 earnings

Positive

+20.0%

Q3 2022

Best reaction

-10.4%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.6%-0.7%-17.3%
Q4 2025+7.3%+7.2%+22.5%
Q3 2025+6.7%+6.1%+7.4%
Q1 2025+9.9%+4.7%+27.0%
Q4 2024-8.6%-8.6%-28.7%
Q3 2024+1.9%+5.7%-17.4%
Q2 2024+0.6%+1.6%+2.4%
Q1 2024-2.4%-2.2%-13.7%
Q4 2023+5.3%-3.0%+14.2%
Q3 2023+1.8%+2.2%+37.7%
Q2 2023-1.6%-1.1%-7.4%
Q1 2023-2.5%+2.8%+26.8%
Q4 2022-0.7%-5.4%-12.5%
Q3 2022+20.0%+66.3%+188.5%
Q2 2022-10.4%-12.5%-14.9%
Q1 2022-3.1%-12.9%-31.5%
Q4 2021+8.1%+1.6%-22.5%
Q3 2021-0.7%-3.8%-12.1%
Q2 2021-4.0%+5.2%+19.4%
Q1 2021-3.9%-3.4%+2.6%
Q2 2020
Q4 2019
Q3 2019
Q2 2019
Q4 2018
Q3 2018
Q2 2018

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