NASDAQ$FDMT

4D Molecular Therapeutics Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

4DMT reported first quarter 2022 financial results and provided corporate updates.

4D Molecular Therapeutics reported first quarter 2022 financial results, including revenue of $1.2 million and a net loss of $26.3 million. The company highlighted progress in its clinical programs and the completion of its commercial-scale GMP manufacturing facility.

  • Dosed the first patient in its Phase 1/2 clinical trial of 4D-710 in patients with cystic fibrosis.
  • Presented updated clinical data from the ongoing Phase 1/2 clinical trial of 4D-310 in patients with Fabry disease at the 18th Annual WORLDSymposium.
  • Presented choroideremia natural history study data at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting.
  • Completed the build out of a commercial-scale GMP manufacturing facility at our Emeryville headquarters which is expected to provide clinical trial material for each of our five product candidates across three therapeutic areas.

Headline financials

Total Revenue

$1.22M

Previous: $2M-39.1%
EPS (adj)

-$0.82

Previous: -$0.61-34.4%
Capital Expenditures

-$6.41M

Previous: -$642K-898.9%
Free Cash Flow

-$32.8M

Previous: -$17M-92.1%
Net Income

-$26.3M

Previous: -$16.4M-60.5%
Operating Income

-$26.4M

Previous: -$16.3M-61.8%
Gross Profit

$1.22M

Previous: $2M-39.1%
Cash & Equivalents

$285M

Previous: $260M+9.5%
Total Assets

$325M

No prior period
Stock-Based Comp

$3.93M

No prior period

Revenue & EPS history

4DMT · Revenue · Quarterly

$1.22M

Q1 2022-39%vs Q1 2021
Beat estimate in 3 of 7 quarters(43%)
ActualEstimate

Revenue by segment

4DMT · $1.22M total across 1 segment · Q1 2022

  • Collaboration & license rev.
    $1.22M

Forward guidance

4D Molecular Therapeutics provided updates on expected upcoming milestones, including initial clinical data from the 4D-150 Phase 1/2 clinical trial for wet AMD in mid-2023 and a clinical data update from the 4D-310 Phase 1/2 clinical trial of 4D-310 in Fabry disease in the first half of 2023.

Tailwinds

  • Provide initial clinical data from the 4D-150 Phase 1/2 clinical trial for wet AMD in mid-2023
  • Provide clinical data update from the 4D-310 Phase 1/2 clinical trial of 4D-310 in Fabry disease in the first half of 2023
  • Continue enrollment and follow-up in the 4D-710 Phase 1/2 clinical trial for cystic fibrosis
  • Continue enrollment and follow-up in the Phase 1/2 clinical trials for both 4D-125 for X-linked retinitis pigmentosa and 4D-110 for choroideremia and provide program updates in the first half of 2023

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+1.0%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+8.5%

Avg return

30 days after

45%

9 / 20 earnings

Positive

+20.0%

Q3 2022

Best reaction

-10.4%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.6%-0.7%-17.3%
Q4 2025+7.3%+7.2%+22.5%
Q3 2025+6.7%+6.1%+7.4%
Q1 2025+9.9%+4.7%+27.0%
Q4 2024-8.6%-8.6%-28.7%
Q3 2024+1.9%+5.7%-17.4%
Q2 2024+0.6%+1.6%+2.4%
Q1 2024-2.4%-2.2%-13.7%
Q4 2023+5.3%-3.0%+14.2%
Q3 2023+1.8%+2.2%+37.7%
Q2 2023-1.6%-1.1%-7.4%
Q1 2023-2.5%+2.8%+26.8%
Q4 2022-0.7%-5.4%-12.5%
Q3 2022+20.0%+66.3%+188.5%
Q2 2022-10.4%-12.5%-14.9%
Q1 2022-3.1%-12.9%-31.5%
Q4 2021+8.1%+1.6%-22.5%
Q3 2021-0.7%-3.8%-12.1%
Q2 2021-4.0%+5.2%+19.4%
Q1 2021-3.9%-3.4%+2.6%
Q2 2020
Q4 2019
Q3 2019
Q2 2019
Q4 2018
Q3 2018
Q2 2018

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