NASDAQ$EVLO

Evelo Biosciences Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Evelo Biosciences reported financial results for Q4 2022 and provided business highlights.

Evelo Biosciences reported a net loss of $23.5 million for the fourth quarter of 2022, with cash and cash equivalents totaling $47.9 million as of December 31, 2022. The company progressed its SINTAX platform and clinical pipeline, with upcoming clinical milestones expected in 2023.

  • Continued progress on the SINTAX platform and clinical pipeline.
  • Demonstrated that SINTAX medicines generate systemically circulating regulatory T cells.
  • Developed a faster release capsule to improve drug substance exposure.
  • Initiated a Phase 2 study of EDP2939 in moderate plaque psoriasis patients, with results expected in the second half of 2023.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$4.20

Previous: -$10.80+61.1%
Capital Expenditures

-$228K

No prior period
Free Cash Flow

-$23.4M

No prior period
Net Income

-$23.5M

Previous: -$28.7M+17.8%
Operating Income

-$21.1M

Previous: -$27.6M+23.5%
Gross Profit

-$1.25M

Previous: $0.00
Cash & Equivalents

$47.9M

Previous: $68.4M-30.0%
Total Assets

$64.4M

No prior period
R&D Expense

$16.1M

Previous: $18.9M-14.8%

Revenue & EPS history

Evelo · Revenue · Quarterly

$0

Q4 2022

Forward guidance

Evelo anticipates data from a fourth patient cohort of the Phase 2 study in atopic dermatitis evaluating the faster release capsule in 2Q 2023 and data from the Phase 2 portion of the trial with EDP2939 in psoriasis expected 2H 2023.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

+1.3%

Avg return

Earnings day

-1.4%

Avg return

5 days after

-9.7%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+32.3%

Q2 2023

Best reaction

-20.3%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2023+0.0%+0.0%-9.8%
Q3 2023-7.6%+4.5%+3.8%
Q2 2023+32.3%-30.5%-41.0%
Q1 2023+2.9%+10.2%-28.8%
Q4 2022-17.8%-27.0%-46.9%
Q3 2022+3.3%-3.3%-8.5%
Q2 2022-7.1%-10.5%-25.4%
Q1 2022-20.3%-14.5%-2.4%
Q4 2021+29.4%+13.5%-26.3%
Q3 2021+10.2%+27.0%+6.0%
Q2 2021-0.9%+5.0%+20.7%
Q1 2021+8.8%-14.4%+11.0%
Q4 2020+14.5%+21.2%+1.6%
Q3 2020-12.9%-5.9%+14.0%
Q2 2020-1.6%-0.5%+15.2%
Q1 2020-5.7%-14.0%-20.9%
Q4 2019+1.8%+12.2%-28.4%
Q3 2019-3.3%-6.1%-35.9%
Q2 2019+3.9%-2.2%+7.0%
Q1 2019+0.8%-1.5%-11.8%
Q4 2018+1.3%+3.0%-6.9%
Q3 2018+0.2%+3.4%+3.7%
Q2 2018-3.4%-5.9%+2.6%
Q1 2018+1.8%+2.2%-24.8%
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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