NASDAQ$EVLO

Evelo Biosciences Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported positive data for EDP1815 in psoriasis and advanced EDP1815 towards later-stage clinical trials.

Evelo Biosciences reported first quarter 2022 financial results, highlighting positive data for EDP1815 in psoriasis and the advancement of EDP1815 towards later-stage clinical trials. The company's cash and cash equivalents were $39.6 million as of March 31, 2022.

  • Reported positive data for EDP1815 in psoriasis, demonstrating effects on systemic inflammatory cytokine markers.
  • Showed depth and duration of response at 6-month follow-up post dosing for EDP1815 in psoriasis.
  • Observed increased target site engagement with a faster release capsule for EDP1815 in psoriasis.
  • Recruitment is ahead of plan in Phase 2 trial of EDP1815 in atopic dermatitis, with data expected in Q1 and Q2 2023.

Headline financials

EPS (adj)

-$11.20

Previous: -$11.00-1.8%
Net Income

-$29.9M

Previous: -$28.2M-5.9%
Operating Income

-$28.7M

Previous: -$27.5M-4.6%
Gross Profit

$0.00

Previous: $0.00
Cash & Equivalents

$39.6M

Previous: $125M-68.2%
R&D Expense

$19.3M

Previous: $21.5M-10.2%

Revenue & EPS history

Evelo · Revenue · Quarterly

$0

Q3 2023

Forward guidance

Evelo Biosciences anticipates data from the first 3 cohorts of the Phase 2 atopic dermatitis trial in mild, moderate, and severe atopic dermatitis in 1Q 2023, with data from a potential additional fourth cohort anticipated in 2Q 2023. The company also plans to initiate clinical development of EDP2939 in 3Q 2022 and expects Phase 2 data from a cohort of patients with psoriasis in 2H 2023.

Tailwinds

  • Anticipates data from the first 3 cohorts of the Phase 2 atopic dermatitis trial in 1Q 2023.
  • Potential data from a fourth cohort in the Phase 2 atopic dermatitis trial anticipated in 2Q 2023.
  • Plans to initiate clinical development of EDP2939 in 3Q 2022.
  • Expects Phase 2 data from a cohort of patients with psoriasis in 2H 2023.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+1.3%

Avg return

Earnings day

-1.4%

Avg return

5 days after

-9.7%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+32.3%

Q2 2023

Best reaction

-20.3%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2023+0.0%+0.0%-9.8%
Q3 2023-7.6%+4.5%+3.8%
Q2 2023+32.3%-30.5%-41.0%
Q1 2023+2.9%+10.2%-28.8%
Q4 2022-17.8%-27.0%-46.9%
Q3 2022+3.3%-3.3%-8.5%
Q2 2022-7.1%-10.5%-25.4%
Q1 2022-20.3%-14.5%-2.4%
Q4 2021+29.4%+13.5%-26.3%
Q3 2021+10.2%+27.0%+6.0%
Q2 2021-0.9%+5.0%+20.7%
Q1 2021+8.8%-14.4%+11.0%
Q4 2020+14.5%+21.2%+1.6%
Q3 2020-12.9%-5.9%+14.0%
Q2 2020-1.6%-0.5%+15.2%
Q1 2020-5.7%-14.0%-20.9%
Q4 2019+1.8%+12.2%-28.4%
Q3 2019-3.3%-6.1%-35.9%
Q2 2019+3.9%-2.2%+7.0%
Q1 2019+0.8%-1.5%-11.8%
Q4 2018+1.3%+3.0%-6.9%
Q3 2018+0.2%+3.4%+3.7%
Q2 2018-3.4%-5.9%+2.6%
Q1 2018+1.8%+2.2%-24.8%
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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