NASDAQ$ENTA

Enanta Pharmaceuticals Inc · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Enanta Pharmaceuticals reported its financial results for the fiscal first quarter ended December 31, 2024, showing a decrease in revenue and net loss compared to the previous year.

Enanta Pharmaceuticals reported a net loss of $22.3 million for the fiscal first quarter ended December 31, 2024, with total revenue of $17.0 million, primarily from MAVYRET®/MAVIRET® royalties. The company is on track with its RSV and immunology programs, with key data readouts and development candidate selections expected in 2025.

  • Total revenue for the quarter was $17.0 million, a decrease from $18.0 million in the same period last year.
  • The company reported a net loss of $22.3 million, or $1.05 per diluted common share, an improvement from a net loss of $33.4 million in the prior year.
  • Research and development expenses decreased to $27.7 million from $36.4 million year-over-year.
  • Enanta's cash, cash equivalents, and short-term marketable securities totaled $216.7 million at December 31, 2024, expected to fund operations into fiscal year 2028.

Headline financials

Total Revenue

$17M

Previous: $18M-5.6%
EPS (adj)

$1.05

Previous: -$1.58+166.5%
Interest Expense

$1.96M

Previous: $3.44M-43.0%
R&D Expenses

$27.7M

Previous: $36.4M-24.0%
G&A Expenses

$12.8M

Previous: $16.5M-22.2%
Interest & Investment Income, Net

$2.8M

Previous: $4.3M-34.9%
Income Tax (Expense) Benefit

$416K

Previous: $622K-33.1%
Total Operating Expenses

$40.5M

No prior period
Net Income

-$22.3M

Previous: -$33.4M+33.3%
Operating Income

-$23.5M

Previous: -$34.9M+32.5%

Revenue & EPS history

Enanta Pharmaceuticals · Revenue · Quarterly

$17M

Q1 2025-5.6%vs Q1 2024
Beat estimate in 4 of 14 quarters(29%)
ActualEstimate

Revenue by segment

Enanta Pharmaceuticals · $18.9M total across 1 segment · Q3 2023

  • Royalty Revenue
    $18.9M-3.0%

Forward guidance

Enanta Pharmaceuticals anticipates a pivotal year in 2025 with significant progress in its RSV and immunology programs, aiming to advance clinical candidates and expand its portfolio, supported by existing cash and future royalty revenue.

Tailwinds

  • On track to report topline results for RSVHR, a Phase 2 study of zelicapavir in high-risk adults infected with RSV, in 3Q 2025.
  • Advancing immunology portfolio with ongoing IND enabling studies of KIT Inhibitor EPS-1421.
  • On track to announce STAT6 Development Candidate in 2H 2025.
  • Expects to select a lead development candidate for STAT6 in the second half of 2025.
  • Plans to expand its presence in immunology with the introduction of a third program in 2025.

Headwinds

  • The company's cash runway is expected to extend into fiscal 2028, implying a finite period without additional funding.
  • The company will evaluate potential partnership opportunities to advance its RSV program, indicating a need for external collaboration for further development.
  • The success of future programs is dependent on achieving clinical milestones and regulatory approvals.
  • The company faces risks related to the impact of development, regulatory, and marketing efforts of others with respect to vaccines and competitive treatments for RSV.
  • There are inherent discovery and development risks associated with Enanta's programs in virology and immunology.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-1.3%

Avg return

Earnings day

-1.2%

Avg return

5 days after

-1.0%

Avg return

30 days after

41%

24 / 58 earnings

Positive

+14.8%

Q4 2021

Best reaction

-29.2%

Q2 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026-6.1%-13.4%-26.0%
Q1 2026+2.2%+0.1%-3.0%
Q4 2025-3.5%-0.7%+13.3%
Q2 2025-5.6%+3.6%+33.5%
Q1 2025+14.1%+45.7%+39.4%
Q4 2024-8.4%-7.9%-34.7%
Q3 2024-6.5%-9.5%-12.7%
Q2 2024-13.6%-16.6%-18.3%
Q1 2024-1.4%-1.7%+22.8%
Q4 2023+9.2%+8.9%-6.7%
Q3 2023-6.6%-19.8%-38.8%
Q2 2023-29.2%-29.7%-27.0%
Q1 2023-0.5%+0.2%-12.1%
Q4 2022-2.9%-11.2%+0.3%
Q3 2022-3.8%-4.2%-10.4%
Q2 2022-1.9%-13.2%-24.4%
Q1 2022+2.8%+1.8%+3.9%
Q4 2021+14.8%+22.0%+2.7%
Q3 2021+5.6%+6.3%+35.8%
Q2 2021-6.9%-5.6%-8.5%
Q1 2021+3.1%-3.3%-3.9%
Q4 2020-1.6%-1.5%-2.9%
Q3 2020-2.1%+0.2%+4.4%
Q2 2020-0.6%+1.8%-0.5%
Q1 2020-0.1%-5.4%-2.3%
Q4 2019-1.8%+1.1%+3.4%
Q3 2019+6.0%+7.4%+0.7%
Q2 2019-0.0%-3.2%+0.5%
Q1 2019+11.6%+11.2%+22.9%
Q4 2018+1.5%+0.2%-11.1%
Q3 2018-6.4%-6.3%-11.4%
Q2 2018-4.5%-3.6%+7.7%
Q1 2018-19.0%-16.7%-7.5%
Q4 2017-5.9%-1.4%+18.0%
Q3 2017+2.2%+2.0%+11.6%
Q2 2017+9.3%+8.0%-3.3%
Q1 2017-6.5%-7.5%-8.9%
Q4 2016+7.4%+9.0%+10.0%
Q3 2016+2.3%+6.4%+4.3%
Q2 2016-1.8%
Q1 2016+1.8%
Q4 2015-2.0%
Q3 2015-13.8%
Q2 2015-0.1%
Q1 2015-4.2%
Q4 2014+4.3%
Q3 2014+4.6%
Q2 2014+5.2%
Q1 2014-3.6%
Q1 2013-3.6%
Q4 2011-22.6%
Q1 2012-22.6%
Q4 2013+8.5%
Q3 2013+7.4%
Q3 2012+7.4%
Q2 2012+5.5%
Q4 2012+5.5%
Q2 2013+0.7%

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