NASDAQ$EDIT

Editas Medicine Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Editas Medicine's Q4 2022 results reflected increased research and development expenses and a decrease in collaboration revenue, leading to a higher net loss compared to the same period in 2021.

Editas Medicine reported a net loss of $60.7 million, or $0.88 per share, for the fourth quarter of 2022. Collaboration and other research and development revenues decreased, while research and development expenses increased due to investments in the EDIT-301 program.

  • Parallel patient dosing commenced in the EDIT-301 RUBY trial for SCD.
  • Clinical update for RUBY trial expected by mid-2023, with plans to dose 20 total patients by year-end.
  • First patient dosing in EDIT-301 EDITHAL trial for TDT is on track for Q1 2023, with a clinical update expected by year-end.
  • Agreement reached to sell iNK cell franchise and out-license gene editing technologies to Shoreline Biosciences.

Headline financials

Total Revenue

$6.54M

Previous: $12.5M-47.6%
EPS (adj)

-$0.88

Previous: -$0.61-44.3%
Capital Expenditures

$624K

Previous: $2.85M-78.1%
Free Cash Flow

-$42.9M

Previous: -$37.4M-14.6%
Net Income

-$60.7M

Previous: -$41.4M-46.6%
Operating Income

-$63.4M

Previous: -$41.6M-52.5%
Gross Profit

$4.96M

Previous: $11M-54.7%
Cash & Equivalents

$437M

Previous: $620M-29.4%
Total Assets

$514M

Previous: $677M-24.1%
Stock-Based Comp

$5.36M

Previous: $7.66M-29.9%

Revenue & EPS history

Editas · Revenue · Quarterly

$6.54M

Q4 2022-47.6%vs Q4 2021
Beat estimate in 7 of 14 quarters(50%)
ActualEstimate

Revenue by segment

Editas · $5.34M total across 1 segment · Q3 2023

  • Collaboration & R&D
    $5.34M+12604.8%

Forward guidance

Editas Medicine is focused on advancing its EDIT-301 program for SCD and TDT, with key milestones expected in 2023. The company also aims to sharpen its focus, strengthen its technology, and expand business development efforts.

Tailwinds

  • On track to provide clinical update for RUBY trial by mid-2023 and dose 20 total patients by year-end.
  • On track to dose first patient in EDIT-301 EDITHAL trial for TDT in Q1 2023 and provide clinical update by year-end.
  • Entering 2023 with the objective of positioning Editas as a leader in programable in vivo gene editing.
  • Bristol Myers Squibb (BMS) recently opted into three additional gene editing programs under the collaboration agreement with Editas Medicine
  • Existing cash, cash equivalents and marketable securities will fund operating expenses and capital expenditures into 2025.

Headwinds

  • Pausing enrollment in the BRILLIANCE trial and seeking a collaboration partner.
  • Net loss attributable to common stockholders was $60.7 million, or $0.88 per share
  • Collaboration and other research and development revenues decreased by $6.0 million
  • Research and development expenses increased by $14.4 million
  • General and administrative expenses increased by $1.5 million

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

+4.5%

Avg return

Earnings day

+4.4%

Avg return

5 days after

+2.0%

Avg return

30 days after

71%

29 / 41 earnings

Positive

+29.4%

Q2 2021

Best reaction

-11.8%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.3%+3.7%-0.7%
Q4 2025+15.5%+22.0%+38.0%
Q3 2025+1.4%+5.3%+5.3%
Q1 2025-2.7%-1.9%+41.6%
Q4 2024+16.5%-11.4%-41.5%
Q3 2024+7.2%+7.2%-31.6%
Q2 2024-10.0%-16.2%-23.3%
Q1 2024-2.1%+0.5%-6.7%
Q4 2023+13.5%+12.0%-16.3%
Q3 2023+18.2%+19.5%+53.2%
Q2 2023+7.6%-2.5%+5.0%
Q1 2023+10.3%+14.6%+10.9%
Q4 2022+2.3%-1.5%-18.7%
Q3 2022-8.5%-13.4%-19.6%
Q2 2022+16.2%+16.1%-10.0%
Q1 2022+2.7%-21.7%-16.0%
Q4 2021+17.3%+21.4%+30.2%
Q3 2021+8.2%+1.1%-14.9%
Q2 2021+29.4%+37.9%+62.1%
Q1 2021-0.9%-9.7%-2.9%
Q4 2020-11.8%-8.1%-18.6%
Q3 2020+0.1%-1.9%+13.3%
Q2 2020+6.8%+5.2%-6.2%
Q1 2020-1.2%+1.9%+6.6%
Q4 2019-6.7%+1.1%-11.2%
Q3 2019+12.8%+12.1%+47.8%
Q2 2019+2.4%+3.8%+1.1%
Q1 2019-2.8%-5.5%-20.4%
Q4 2018+12.8%+12.8%+16.7%
Q3 2018+10.7%+4.1%+4.8%
Q2 2018+0.5%+3.3%+11.6%
Q1 2018+1.0%+2.4%+13.2%
Q4 2017+9.9%+14.6%-14.5%
Q3 2017-6.9%+1.5%+7.3%
Q2 2017+4.6%+22.8%+6.5%
Q1 2017-5.1%-7.2%-17.1%
Q4 2016+4.4%+19.2%+0.8%
Q3 2016+5.1%+23.6%+19.4%
Q2 2016-9.3%-15.1%-27.4%
Q1 2016+7.0%
Q4 2015+5.9%
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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