NASDAQ$EDIT

Editas Medicine Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Editas Medicine reported a net loss and increased collaboration revenue for Q4 2021.

Editas Medicine reported a net loss of $41.4 million for the fourth quarter of 2021, with collaboration and other research and development revenues increasing to $12.5 million. The company's cash, cash equivalents, and marketable securities totaled $619.9 million as of December 31, 2021, expected to fund operations through 2023.

  • EDIT-101 Phase 1/2 BRILLIANCE trial enrolling mid-dose pediatric cohort; clinical data update expected in 2H 2022
  • EDIT-301 remains on track to dose first sickle cell disease patient in 1H 2022 and first TDT patient in 2022
  • EDIT-103 for RHO-adRP and EDIT-202 for solid tumors advancing towards IND-enabling studies
  • First ever in vivo ocular gene editing data demonstrated evidence of gene editing and potential clinical benefit; clinical update expected in 2H 2022

Headline financials

Total Revenue

$12.5M

Previous: $11.4M+9.2%
EPS (adj)

-$0.61

Previous: -$1.00+39.0%
Capital Expenditures

$2.85M

Previous: $1.38M+106.8%
Free Cash Flow

-$37.4M

Previous: -$41.5M+9.8%
Net Income

-$41.4M

Previous: -$62.5M+33.7%
Operating Income

-$41.6M

Previous: -$65.9M+36.8%
Gross Profit

$11M

Previous: -$50.1M+121.9%
Cash & Equivalents

$620M

Previous: $512M+21.1%
Total Assets

$677M

Previous: $573M+18.3%
Stock-Based Comp

$7.66M

Previous: $5.67M+35.0%

Revenue & EPS history

Editas · Revenue · Quarterly

$12.5M

Q4 2021+9.2%vs Q4 2020
Beat estimate in 11 of 16 quarters(69%)
ActualEstimate

Revenue by segment

Editas · $5.34M total across 1 segment · Q3 2023

  • Collaboration & R&D
    $5.34M+12604.8%

Forward guidance

Editas Medicine anticipates several milestones in 2022, including clinical data updates for EDIT-101 and EDIT-301, the start of patient dosing in the beta thalassemia trial, and the beginning of IND-enabling studies for EDIT-202.

Tailwinds

  • Completing dosing of the pediatric mid-dose cohort in the first half of 2022
  • Initiating dosing of the pediatric high-dose cohort in the BRILLIANCE trial in 2022
  • Establishing registrational trial criteria by year-end 2022
  • Dosing the first patient in the RUBY trial in the first half of 2022
  • Dosing the first TDT patient with EDIT-301 in 2022

Headwinds

  • Uncertainties inherent in the initiation and completion of pre-clinical studies and clinical trials
  • Availability and timing of results from pre-clinical studies and clinical trials
  • Whether interim results from a clinical trial will be predictive of the final results of the trial or the results of future trials
  • Expectations for regulatory approvals to conduct trials or to market products
  • Availability of funding sufficient for the Company’s foreseeable and unforeseeable operating expenses and capital expenditure requirements

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+4.5%

Avg return

Earnings day

+4.4%

Avg return

5 days after

+2.0%

Avg return

30 days after

71%

29 / 41 earnings

Positive

+29.4%

Q2 2021

Best reaction

-11.8%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.3%+3.7%-0.7%
Q4 2025+15.5%+22.0%+38.0%
Q3 2025+1.4%+5.3%+5.3%
Q1 2025-2.7%-1.9%+41.6%
Q4 2024+16.5%-11.4%-41.5%
Q3 2024+7.2%+7.2%-31.6%
Q2 2024-10.0%-16.2%-23.3%
Q1 2024-2.1%+0.5%-6.7%
Q4 2023+13.5%+12.0%-16.3%
Q3 2023+18.2%+19.5%+53.2%
Q2 2023+7.6%-2.5%+5.0%
Q1 2023+10.3%+14.6%+10.9%
Q4 2022+2.3%-1.5%-18.7%
Q3 2022-8.5%-13.4%-19.6%
Q2 2022+16.2%+16.1%-10.0%
Q1 2022+2.7%-21.7%-16.0%
Q4 2021+17.3%+21.4%+30.2%
Q3 2021+8.2%+1.1%-14.9%
Q2 2021+29.4%+37.9%+62.1%
Q1 2021-0.9%-9.7%-2.9%
Q4 2020-11.8%-8.1%-18.6%
Q3 2020+0.1%-1.9%+13.3%
Q2 2020+6.8%+5.2%-6.2%
Q1 2020-1.2%+1.9%+6.6%
Q4 2019-6.7%+1.1%-11.2%
Q3 2019+12.8%+12.1%+47.8%
Q2 2019+2.4%+3.8%+1.1%
Q1 2019-2.8%-5.5%-20.4%
Q4 2018+12.8%+12.8%+16.7%
Q3 2018+10.7%+4.1%+4.8%
Q2 2018+0.5%+3.3%+11.6%
Q1 2018+1.0%+2.4%+13.2%
Q4 2017+9.9%+14.6%-14.5%
Q3 2017-6.9%+1.5%+7.3%
Q2 2017+4.6%+22.8%+6.5%
Q1 2017-5.1%-7.2%-17.1%
Q4 2016+4.4%+19.2%+0.8%
Q3 2016+5.1%+23.6%+19.4%
Q2 2016-9.3%-15.1%-27.4%
Q1 2016+7.0%
Q4 2015+5.9%
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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