NASDAQ$DYN
Dyne Therapeutics Inc · Q4 2025 earnings
Q4 2025 earnings · · Before market open · Investor relations
Briefing
DYN reported Q4 2025, a net loss of $112M, diluted EPS of $-0.76.
For Q4 2025, DYN reported a net loss of $112M, diluted EPS was $-0.76. Management discusses segment performance, capital allocation, and macro risks in the quarterly filing.
- Net loss $112M.
- Diluted EPS $-0.76.
- DYN MD&A covers liquidity, operating priorities, and sector risks.
Headline financials
Revenue & EPS history
Dyne Therapeutics · Revenue · Quarterly
$0
Forward guidance
BLA for z-rostudirsen accelerated approval planned Q2 2026; potential U.S. launch Q1 2027.
Tailwinds
- Cash $1.1B with runway into Q1 2028.
- Positive DELIVER registrational cohort dystrophin data.
Headwinds
- Q4 net loss $112M on elevated R&D.
- Clinical and regulatory execution risk on DMD/DM1 programs.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2025
+1.8%
Avg return
Earnings day
-2.5%
Avg return
5 days after
+3.0%
Avg return
30 days after
59%
13 / 22 earnings
Positive
+21.3%
Q3 2024
Best reaction
-6.5%
Q4 2020
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2025 | +3.6% | -4.9% | +15.9% | |
| Q3 2025 | -2.8% | -14.0% | -5.8% | |
| Q2 2025 | -1.3% | +7.9% | +47.7% | |
| Q1 2025 | +1.1% | +3.6% | +30.1% | |
| Q4 2024 | -4.5% | -13.8% | -17.0% | |
| Q3 2024 | +21.3% | +0.9% | -9.0% | |
| Q2 2024 | +0.5% | +5.7% | -22.0% | |
| Q1 2024 | +1.0% | -0.7% | +23.4% | |
| Q4 2023 | -3.4% | -9.2% | -4.5% | |
| Q3 2023 | +6.5% | +24.3% | +66.0% | |
| Q2 2023 | -1.8% | -15.6% | +0.1% | |
| Q1 2023 | -4.0% | -4.6% | -7.4% | |
| Q4 2022 | +10.1% | +8.3% | -15.5% | |
| Q3 2022 | +1.6% | -4.9% | +15.8% | |
| Q2 2022 | +4.3% | +1.1% | +1.0% | |
| Q1 2022 | +10.5% | -16.4% | -45.0% | |
| Q4 2021 | -1.7% | -2.9% | +16.5% | |
| Q3 2021 | +2.0% | +0.7% | -10.4% | |
| Q2 2021 | +3.3% | -4.1% | -9.6% | |
| Q1 2021 | +5.1% | +0.2% | +1.9% | |
| Q4 2020 | -6.5% | -6.2% | -4.4% | |
| Q3 2020 | -5.0% | -9.6% | -1.5% | |
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