NASDAQ$DYN

Dyne Therapeutics Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Reported financial results for the fourth quarter and full year 2022 and business highlights.

Dyne Therapeutics reported a net loss of $38.8 million for the quarter ended December 31, 2022, with cash, cash equivalents, and marketable securities totaling $256.0 million, expected to fund operations through 2024.

  • Enrollment continues in ACHIEVE, a Phase 1/2 global clinical trial evaluating DYNE-101 in adult patients with myotonic dystrophy type 1 (DM1).
  • Enrollment continues in DELIVER, a Phase 1/2 global clinical trial evaluating DYNE-251 in males with Duchenne muscular dystrophy (DMD) who have mutations amenable to exon 51 skipping therapy.
  • Dyne anticipates reporting initial data in the second half of 2023 from the ACHIEVE trial of DYNE-101 in DM1 on safety, tolerability and splicing.
  • Dyne anticipates reporting initial data in the second half of 2023 from the DELIVER trial of DYNE-251 in DMD on safety, tolerability and dystrophin.

Headline financials

EPS (adj)

-$0.74

Previous: -$1.00+26.0%
Capital Expenditures

$519K

Previous: $1.99M-73.9%
Free Cash Flow

-$29.7M

Previous: -$30.1M+1.2%
Net Income

-$38.8M

Previous: -$51.8M+25.0%
Operating Income

-$40.1M

Previous: -$52M+22.7%
Cash & Equivalents

$256M

Previous: $377M-32.0%
Total Assets

$306M

Previous: $426M-28.0%
Stock-Based Comp

$3.83M

Previous: $6.01M-36.3%

Revenue & EPS history

Dyne Therapeutics · Revenue · Quarterly

$0

Q4 2025
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Dyne anticipates reporting initial data in the second half of 2023 from the ACHIEVE trial of DYNE-101 in DM1 and the DELIVER trial of DYNE-251 in DMD. Cash position is expected to fund operations through 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

+1.8%

Avg return

Earnings day

-2.5%

Avg return

5 days after

+3.0%

Avg return

30 days after

59%

13 / 22 earnings

Positive

+21.3%

Q3 2024

Best reaction

-6.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026———
Q4 2025+3.6%-4.9%+15.9%
Q3 2025-2.8%-14.0%-5.8%
Q2 2025-1.3%+7.9%+47.7%
Q1 2025+1.1%+3.6%+30.1%
Q4 2024-4.5%-13.8%-17.0%
Q3 2024+21.3%+0.9%-9.0%
Q2 2024+0.5%+5.7%-22.0%
Q1 2024+1.0%-0.7%+23.4%
Q4 2023-3.4%-9.2%-4.5%
Q3 2023+6.5%+24.3%+66.0%
Q2 2023-1.8%-15.6%+0.1%
Q1 2023-4.0%-4.6%-7.4%
Q4 2022+10.1%+8.3%-15.5%
Q3 2022+1.6%-4.9%+15.8%
Q2 2022+4.3%+1.1%+1.0%
Q1 2022+10.5%-16.4%-45.0%
Q4 2021-1.7%-2.9%+16.5%
Q3 2021+2.0%+0.7%-10.4%
Q2 2021+3.3%-4.1%-9.6%
Q1 2021+5.1%+0.2%+1.9%
Q4 2020-6.5%-6.2%-4.4%
Q3 2020-5.0%-9.6%-1.5%
Q2 2020———
Q1 2020———
Q4 2019———
Q3 2019———
Q2 2019———
Q1 2019———
Q4 2017———
Q3 2017———
Q2 2017———
Q1 2017———
Q4 2016———
Q3 2016———
Q2 2016———
Q1 2016———
Q4 2015———
Q3 2015———
Q2 2015———
Q1 2015———
Q4 2014———
Q3 2014———
Q2 2014———
Q1 2014———
Q4 2013———
Q3 2013———
Q2 2013———
Q1 2013———
Q4 2012———
Q3 2012———
Q2 2012———
Q1 2012———
Q4 2011———
Q3 2011———
Q2 2011———
Q1 2011———
Q4 2010———
Q3 2010———
Q2 2010———
Q1 2010———

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