NASDAQ$DYN

Dyne Therapeutics Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported financial results for the first quarter of 2022 and business highlights.

Dyne Therapeutics reported a net loss of $35.6 million for the first quarter of 2022. The company's cash, cash equivalents, and marketable securities totaled $323.2 million as of March 31, 2022.

  • Initiation of patient dosing in multiple ascending dose clinical trials for DYNE-251 in DMD and DYNE-101 in DM1 anticipated in mid-2022.
  • Response to FDA relating to IND for DYNE-251 in DMD is expected to be submitted in the second quarter.
  • Regulatory filings in multiple countries for DYNE-101 in DM1 are expected to be submitted in the second quarter.
  • Cash, cash equivalents and marketable securities were $323.2 million as of March 31, 2022, which is anticipated to fund operations into the second half of 2024.

Headline financials

EPS (adj)

-$0.69

Previous: -$0.50-38.0%
Research and Development Expenses

$28.2M

No prior period
General and Administrative Expenses

$7.55M

No prior period
Capital Expenditures

$1.4M

No prior period
Free Cash Flow

-$52.1M

No prior period
Net Income

-$35.6M

Previous: -$25M-42.5%
Operating Income

-$35.8M

No prior period
Cash & Equivalents

$323M

Previous: $483M-33.1%
Total Assets

$388M

No prior period
Stock-Based Comp

$4.49M

No prior period

Revenue & EPS history

Dyne Therapeutics · Revenue · Quarterly

$0

Q4 2025
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Dyne expects to submit an IND for DYNE-301 in FSHD in the second half of 2022 and anticipates initiating patient dosing in global multiple ascending dose (MAD) clinical trials for DYNE-251 in DMD and DYNE-101 in DM1 in mid-2022.

Tailwinds

  • Submitting response to the FDA’s clinical hold letter for DYNE-251 in DMD in Q2 2022
  • Submitting regulatory filings in multiple countries for DYNE-101 in DM1 in Q2 2022
  • Initiating patient dosing in global multiple ascending dose (MAD) clinical trials for DYNE-251 in DMD in mid-2022
  • Initiating patient dosing in global multiple ascending dose (MAD) clinical trials for DYNE-101 in DM1 in mid-2022
  • Submitting an IND for DYNE-301 in FSHD in the second half of 2022

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+1.8%

Avg return

Earnings day

-2.5%

Avg return

5 days after

+3.0%

Avg return

30 days after

59%

13 / 22 earnings

Positive

+21.3%

Q3 2024

Best reaction

-6.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+3.6%-4.9%+15.9%
Q3 2025-2.8%-14.0%-5.8%
Q2 2025-1.3%+7.9%+47.7%
Q1 2025+1.1%+3.6%+30.1%
Q4 2024-4.5%-13.8%-17.0%
Q3 2024+21.3%+0.9%-9.0%
Q2 2024+0.5%+5.7%-22.0%
Q1 2024+1.0%-0.7%+23.4%
Q4 2023-3.4%-9.2%-4.5%
Q3 2023+6.5%+24.3%+66.0%
Q2 2023-1.8%-15.6%+0.1%
Q1 2023-4.0%-4.6%-7.4%
Q4 2022+10.1%+8.3%-15.5%
Q3 2022+1.6%-4.9%+15.8%
Q2 2022+4.3%+1.1%+1.0%
Q1 2022+10.5%-16.4%-45.0%
Q4 2021-1.7%-2.9%+16.5%
Q3 2021+2.0%+0.7%-10.4%
Q2 2021+3.3%-4.1%-9.6%
Q1 2021+5.1%+0.2%+1.9%
Q4 2020-6.5%-6.2%-4.4%
Q3 2020-5.0%-9.6%-1.5%
Q2 2020
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019
Q4 2017
Q3 2017
Q2 2017
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q4 2012
Q3 2012
Q2 2012
Q1 2012
Q4 2011
Q3 2011
Q2 2011
Q1 2011
Q4 2010
Q3 2010
Q2 2010
Q1 2010

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