NASDAQ$DYN

Dyne Therapeutics Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported financial results for the first quarter of 2022 and business highlights.

Dyne Therapeutics reported a net loss of $35.6 million for the first quarter of 2022. The company's cash, cash equivalents, and marketable securities totaled $323.2 million as of March 31, 2022.

  • Initiation of patient dosing in multiple ascending dose clinical trials for DYNE-251 in DMD and DYNE-101 in DM1 anticipated in mid-2022.
  • Response to FDA relating to IND for DYNE-251 in DMD is expected to be submitted in the second quarter.
  • Regulatory filings in multiple countries for DYNE-101 in DM1 are expected to be submitted in the second quarter.
  • Cash, cash equivalents and marketable securities were $323.2 million as of March 31, 2022, which is anticipated to fund operations into the second half of 2024.

Headline financials

EPS (adj)

-$0.69

Previous: -$0.50-38.0%
Research and Development Expenses

$28.2M

No prior period
General and Administrative Expenses

$7.55M

No prior period
Capital Expenditures

$1.4M

No prior period
Free Cash Flow

-$52.1M

No prior period
Net Income

-$35.6M

Previous: -$25M-42.5%
Operating Income

-$35.8M

No prior period
Cash & Equivalents

$323M

Previous: $483M-33.1%
Total Assets

$388M

No prior period
Stock-Based Comp

$4.49M

No prior period

Revenue & EPS history

Dyne Therapeutics · Revenue · Quarterly

$0

Q4 2025
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Dyne expects to submit an IND for DYNE-301 in FSHD in the second half of 2022 and anticipates initiating patient dosing in global multiple ascending dose (MAD) clinical trials for DYNE-251 in DMD and DYNE-101 in DM1 in mid-2022.

Tailwinds

  • Submitting response to the FDA’s clinical hold letter for DYNE-251 in DMD in Q2 2022
  • Submitting regulatory filings in multiple countries for DYNE-101 in DM1 in Q2 2022
  • Initiating patient dosing in global multiple ascending dose (MAD) clinical trials for DYNE-251 in DMD in mid-2022
  • Initiating patient dosing in global multiple ascending dose (MAD) clinical trials for DYNE-101 in DM1 in mid-2022
  • Submitting an IND for DYNE-301 in FSHD in the second half of 2022

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+1.8%

Avg return

Earnings day

-2.5%

Avg return

5 days after

+3.0%

Avg return

30 days after

59%

13 / 22 earnings

Positive

+21.3%

Q3 2024

Best reaction

-6.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026———
Q4 2025+3.6%-4.9%+15.9%
Q3 2025-2.8%-14.0%-5.8%
Q2 2025-1.3%+7.9%+47.7%
Q1 2025+1.1%+3.6%+30.1%
Q4 2024-4.5%-13.8%-17.0%
Q3 2024+21.3%+0.9%-9.0%
Q2 2024+0.5%+5.7%-22.0%
Q1 2024+1.0%-0.7%+23.4%
Q4 2023-3.4%-9.2%-4.5%
Q3 2023+6.5%+24.3%+66.0%
Q2 2023-1.8%-15.6%+0.1%
Q1 2023-4.0%-4.6%-7.4%
Q4 2022+10.1%+8.3%-15.5%
Q3 2022+1.6%-4.9%+15.8%
Q2 2022+4.3%+1.1%+1.0%
Q1 2022+10.5%-16.4%-45.0%
Q4 2021-1.7%-2.9%+16.5%
Q3 2021+2.0%+0.7%-10.4%
Q2 2021+3.3%-4.1%-9.6%
Q1 2021+5.1%+0.2%+1.9%
Q4 2020-6.5%-6.2%-4.4%
Q3 2020-5.0%-9.6%-1.5%
Q2 2020———
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Q4 2019———
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Q4 2016———
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Q4 2015———
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Q4 2014———
Q3 2014———
Q2 2014———
Q1 2014———
Q4 2013———
Q3 2013———
Q2 2013———
Q1 2013———
Q4 2012———
Q3 2012———
Q2 2012———
Q1 2012———
Q4 2011———
Q3 2011———
Q2 2011———
Q1 2011———
Q4 2010———
Q3 2010———
Q2 2010———
Q1 2010———

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