NASDAQ$DNLI

Denali Therapeutics Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

DNLI reported Q4 2024 revenue of $330.5M.

For Q4 2024, DNLI reported Revenue was $330.5M. Management discusses operating trends, liquidity, and outlook in the filing.

  • Revenue $330.5M for Q4 2024.
  • MD&A highlights operating priorities, liquidity, and sector risks.
  • MD&A highlights operating priorities, liquidity, and sector risks.

Headline financials

Total Revenue

$331M

Previous: -$305M+208.3%
EPS (adj)

-$0.67

Previous: -$0.86+22.1%
Cash & Mkt. Securities

$1.19B

No prior period
Net Income

-$115M

Previous: -$119M+4.0%
Operating Income

-$130M

Previous: -$133M+2.1%

Revenue & EPS history

Denali Therapeutics · Revenue · Quarterly

$331M

Q4 2024-208.3%vs Q4 2023
Beat estimate in 6 of 14 quarters(43%)
ActualEstimate

Forward guidance

The filing discusses operating priorities, capital allocation, and demand trends.

Tailwinds

  • Management outlines strategic priorities and cost actions.
  • Segment commentary supports the earnings narrative.

Headwinds

  • Macro, rates, or input costs may pressure margins.
  • One-time items can affect year-over-year comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

-0.3%

Avg return

Earnings day

-1.4%

Avg return

5 days after

+1.3%

Avg return

30 days after

44%

14 / 32 earnings

Positive

+19.7%

Q4 2023

Best reaction

-13.7%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-1.0%-4.9%-15.2%
Q3 2025-3.2%+18.1%+34.0%
Q1 2025+1.0%-0.9%+6.1%
Q4 2024-1.5%-15.6%-21.8%
Q3 2024+7.1%+14.2%-10.0%
Q2 2024-10.3%-9.7%+0.3%
Q1 2024+10.3%+6.8%+24.3%
Q4 2023+19.7%+23.5%+21.5%
Q3 2023-2.7%-21.8%-9.7%
Q2 2023-5.2%-7.6%-7.3%
Q1 2023+3.0%+5.4%+16.1%
Q4 2022+4.8%+7.3%-10.9%
Q3 2022-7.8%-10.3%+6.2%
Q2 2022+4.6%+6.6%-17.5%
Q1 2022-13.7%-14.0%-8.5%
Q4 2021-2.8%-7.8%-1.9%
Q3 2021+3.5%-0.4%-19.9%
Q2 2021+3.5%+4.6%+6.6%
Q1 2021-8.0%-10.2%+5.5%
Q4 2020+7.5%-5.8%-17.2%
Q3 2020+5.2%+16.3%+40.8%
Q2 2020+6.1%-5.4%-2.5%
Q1 2020-5.5%-5.7%+2.6%
Q4 2019-8.6%-10.0%-12.5%
Q3 2019-6.1%-10.1%+10.5%
Q2 2019+0.6%+5.4%-4.2%
Q1 2019-4.8%-11.4%-18.9%
Q4 2018+11.7%+12.0%+26.4%
Q3 2018-4.0%-0.6%+12.7%
Q2 2018-0.5%-0.7%+17.0%
Q4 2017-4.8%-5.1%+2.2%
Q1 2018-8.8%-8.0%-12.4%
Q3 2017
Q2 2017
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016

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