NASDAQ$CYRX

CryoPort Inc. · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Cryoport reported Q4 2025 results for its temperature-controlled logistics network.

Cryoport reported fourth-quarter and full-year 2025 financial results for its global biopharma cold-chain logistics and bioservices platform, including revenue growth from cell and gene therapy customers.

  • Cold-chain logistics for biopharma.
  • Cell and gene therapy customer growth.
  • Global network and bioservices expansion.
  • Q4 revenue scale in tens of millions.
  • Partnerships with CDMOs and sponsors.

Headline financials

Total Revenue

$45.5M

Previous: $26M+74.8%
EPS (adj)

-$0.17

Previous: -$0.42+59.2%
Net Income

-$11.6M

Previous: -$18.7M+37.7%
Operating Income

-$10M

Previous: -$13.9M+28.0%
Gross Profit

$21.7M

Previous: $27.3M-20.4%

Revenue & EPS history

CryoPort · Revenue · Quarterly

$45.5M

Q4 2025+74.8%vs Q4 2024
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Forward guidance

2026 outlook on biopharma trial activity and commercial launch logistics demand.

Tailwinds

  • Secular growth in CGT logistics needs.
  • Integrated bioservices cross-sell.
  • High switching costs for validated shippers.

Headwinds

  • Customer trial delays reduce shipments.
  • Operating leverage still developing.
  • Competition from larger logistics players.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+2.2%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+8.5%

Avg return

30 days after

49%

28 / 57 earnings

Positive

+31.6%

Q4 2013

Best reaction

-33.8%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+19.4%+33.2%+58.2%
Q4 2025+2.9%-4.7%+3.3%
Q3 2025-8.2%-7.4%+3.5%
Q1 2025+23.4%+23.3%+23.7%
Q4 2024+30.6%-7.1%+5.7%
Q3 2024-3.6%-0.9%-8.6%
Q2 2024+3.9%+10.0%+9.8%
Q1 2024-17.5%-16.7%-30.6%
Q4 2023-12.3%-7.3%+10.3%
Q3 2023+8.9%+8.4%+46.7%
Q2 2023-0.2%+1.2%-5.0%
Q1 2023+13.9%+4.5%-6.3%
Q4 2022+13.7%+9.9%+15.3%
Q3 2022-33.8%-35.7%-26.5%
Q2 2022+6.8%+5.2%-16.1%
Q1 2022-8.5%-14.6%-2.8%
Q4 2021+9.3%+7.0%+1.9%
Q3 2021-1.0%-1.2%-22.8%
Q2 2021-1.5%-3.6%+2.9%
Q1 2021+9.0%+11.6%-2.4%
Q4 2020-0.7%-11.7%-12.5%
Q3 2020+5.0%+24.2%+12.8%
Q2 2020-2.0%-5.0%+55.5%
Q1 2020+2.0%+17.0%+22.6%
Q4 2019+2.1%+0.8%-11.9%
Q3 2019+1.4%+3.9%+5.6%
Q2 2019+19.7%+24.5%+2.3%
Q1 2019+12.5%+12.5%+17.7%
Q4 2018-0.6%+6.6%+22.3%
Q3 2018-1.0%-9.4%-2.0%
Q2 2018-1.6%-14.7%-6.5%
Q1 2018+11.8%+23.0%+67.4%
Q4 2017+3.8%+6.4%-7.0%
Q3 2017-15.1%-22.9%-10.5%
Q2 2017-2.0%+3.6%+28.6%
Q1 2017+8.2%+9.0%+46.9%
Q4 2016+23.7%+9.0%+23.7%
Q2 2016-7.5%
Q1 2016+10.2%
Q4 2015-3.0%
Q3 2015+7.5%
Q2 2015-14.4%
Q1 2015-2.2%
Q4 2014+6.4%
Q3 2014-5.6%
Q4 2013+31.6%
Q3 2013-8.0%
Q2 2013+5.3%
Q1 2013+0.0%
Q4 2012-3.1%
Q3 2012-10.8%
Q2 2012-8.0%
Q1 2012-2.7%
Q1 2010+11.2%
Q3 2009+1.4%
Q2 2009-2.8%
Q1 2009+0.0%

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