NASDAQ$BMEA

Biomea Fusion Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Reported fourth quarter and full year results, highlighting progress in diabetes and oncology programs.

Biomea Fusion reported a net loss of $34.9 million for Q4 2023 and ended the quarter with $177.2 million in cash, cash equivalents, and restricted cash. The company highlighted positive data from its Phase 2 trial in type 2 diabetes and the initiation of a Phase 2 study in type 1 diabetes.

  • Reported Phase 2 data in type 2 diabetes patients supporting the disease-modifying potential of BMF-219.
  • Initiated a Phase 2 study of BMF-219 in type 1 diabetes patients.
  • Reported initial topline data from Phase 1 study of BMF-219 in acute myeloid leukemia (AML).
  • Ended the fourth quarter of 2023 with a cash position of $177.2 million.

Headline financials

Total Revenue

$6.14M

No prior period
EPS (adj)

-$0.98

Previous: -$0.86-14.0%
Research and Development Expenses

$30.9M

No prior period
General and Administrative Expenses

$6.46M

No prior period
Total Operating Expenses

$37.3M

No prior period
Interest and Other Income, Net

$2.44M

No prior period
Total Stock-Based Compensation Expense

$3.86M

No prior period
Capital Expenditures

-$8K

Previous: $712K-101.1%
Net Income

-$34.9M

Previous: -$25.3M-37.9%
Operating Income

-$37.3M

Previous: -$26.3M-42.1%
Gross Profit

$5.01M

No prior period
R&D Expense

$30.9M

No prior period
Stock-Based Comp

$3.86M

Previous: $2.72M+42.3%

Revenue & EPS history

Biomea Fusion · Revenue · Quarterly

$6.14M

Q4 2023

Forward guidance

Biomea Fusion anticipates key milestones in 2024, including completing enrollment and reporting data from Phase 2 trials in type 2 and type 1 diabetes, advancing oncology programs, and announcing a third development candidate.

Tailwinds

  • Complete and report the results of dosing and follow-up of over 200 type 2 diabetes patients enrolled in Phase 2 expansion cohorts.
  • Report data from 40 patients enrolled in the open label portion of Phase 2 study in type 1 diabetes patients.
  • Complete dose escalation steps in liquid and solid tumor studies of BMF-219 and BMF-500.
  • Establish recommended Phase 2 dose (RP2D) for COVALENT-101 in liquid tumors.
  • Announce a third development candidate from the Biomea FUSION™ Platform technology.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+5.2%

Avg return

Earnings day

+3.3%

Avg return

5 days after

+3.0%

Avg return

30 days after

40%

8 / 20 earnings

Positive

+109.7%

Q4 2022

Best reaction

-16.7%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+15.3%-13.5%-23.7%
Q3 2025-0.7%-4.3%-21.0%
Q2 2025+0.6%-3.2%+21.5%
Q1 2025-1.3%-4.6%+73.0%
Q4 2024+1.2%-7.8%-8.7%
Q3 2024-16.7%-27.2%-43.4%
Q1 2024+6.7%+3.7%-9.1%
Q4 2023-14.4%-14.8%-22.6%
Q3 2023-6.8%-7.9%+16.3%
Q2 2023-2.4%-9.3%-22.2%
Q1 2023-3.3%+2.6%+12.5%
Q4 2022+109.7%+101.0%+84.6%
Q3 2022-15.6%-29.4%-43.3%
Q2 2022+3.3%+11.8%+8.5%
Q1 2022+35.2%+69.4%+127.2%
Q4 2021-13.8%-7.7%-36.2%
Q3 2021+7.6%+2.0%-7.9%
Q2 2021-0.6%-11.0%-3.4%
Q1 2021-0.3%+7.9%-21.4%
Q4 2020-0.3%+7.9%-21.4%
Q3 2020
Q2 2020
Q1 2020

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