NASDAQ$BMEA

Biomea Fusion Inc · Q3 2023 earnings

Q3 2023 earnings · · Investor relations

Briefing

Reported third quarter 2023 financial results and corporate highlights.

Biomea Fusion reported a net loss of $28.4 million for the third quarter of 2023. They had a cash position of $199.5 million at the end of the third quarter. Clinical trials for BMF-219 in type 1 and type 2 diabetes are progressing, and the first patient was dosed with BMF-500 in a Phase I clinical trial.

  • Demonstrated durable HbA1c lowering in the escalation portion of ongoing Phase II study in type 2 diabetes (COVALENT-111).
  • Expansion portion of COVALENT-111 cleared and actively enrolling in the U.S. and Canada; expected to enroll approximately 200 adults with type 2 diabetes.
  • Investigational new drug (IND) application cleared for Phase II clinical trial of BMF-219 in type 1 diabetes (COVALENT-112); enrollment of 150 adults with type 1 diabetes anticipated to begin in Q4 2023.
  • Dosed first relapsed/refractory AML patient with BMF-500, Biomea’s novel third generation investigational oral covalent inhibitor of FMS-like tyrosine kinase 3 (FLT3).

Headline financials

Total Revenue

$0.00

Previous: $1.24B-100.0%
EPS (adj)

-$0.80

Previous: -$0.78-2.6%
Research and Development Expenses

$25.3M

No prior period
General and Administrative Expenses

$5.77M

No prior period
Capital Expenditures

-$39K

Previous: -$318K+87.7%
Free Cash Flow

-$23.9M

Previous: -$23.2M-3.1%
Net Income

-$28.4M

Previous: -$22.9M-24.2%
Operating Income

-$31.1M

Previous: -$23.5M-32.5%
Gross Profit

-$1.11M

Previous: $1.24B-100.1%
Cash & Equivalents

$199M

Previous: $134M+49.1%
Total Assets

$225M

Previous: $145M+55.2%
R&D Expense

$25.3M

No prior period
Stock-Based Comp

$3.6M

Previous: $2.73M+31.7%

Revenue & EPS history

Biomea Fusion · Revenue · Quarterly

$0

Q3 2023-100%vs Q3 2022

Forward guidance

Biomea Fusion is focused on advancing its clinical trials for BMF-219 and BMF-500, with anticipated milestones including reporting topline data for the escalation portion of COVALENT-111 and dosing the first patient in COVALENT-112.

Tailwinds

  • Report topline data for the escalation portion in Q4 2023 to include multiple BMF-219 dosing cohorts.
  • Start enrollment of expansion portion of COVALENT-111 at two dose levels including 100 mg and 200 mg, with a fourth cohort following the completion of the escalation portion.
  • Dose the first patient in COVALENT-112.
  • Report additional details of the clinical data set of AML/ALL patients dosed in the COVALENT-101 study at an upcoming medical conference.
  • Continued site activation and patient enrollment to establish optimal dose levels across all three solid tumor indications (NSCLC, CRC and PDAC with an activating KRAS mutation).

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q3 2023

Historical avgQ3 2023

+5.2%

Avg return

Earnings day

+3.3%

Avg return

5 days after

+3.0%

Avg return

30 days after

40%

8 / 20 earnings

Positive

+109.7%

Q4 2022

Best reaction

-16.7%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+15.3%-13.5%-23.7%
Q3 2025-0.7%-4.3%-21.0%
Q2 2025+0.6%-3.2%+21.5%
Q1 2025-1.3%-4.6%+73.0%
Q4 2024+1.2%-7.8%-8.7%
Q3 2024-16.7%-27.2%-43.4%
Q1 2024+6.7%+3.7%-9.1%
Q4 2023-14.4%-14.8%-22.6%
Q3 2023-6.8%-7.9%+16.3%
Q2 2023-2.4%-9.3%-22.2%
Q1 2023-3.3%+2.6%+12.5%
Q4 2022+109.7%+101.0%+84.6%
Q3 2022-15.6%-29.4%-43.3%
Q2 2022+3.3%+11.8%+8.5%
Q1 2022+35.2%+69.4%+127.2%
Q4 2021-13.8%-7.7%-36.2%
Q3 2021+7.6%+2.0%-7.9%
Q2 2021-0.6%-11.0%-3.4%
Q1 2021-0.3%+7.9%-21.4%
Q4 2020-0.3%+7.9%-21.4%
Q3 2020
Q2 2020
Q1 2020

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